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Protein
Submitted name:

Alanine racemase

Gene

Oweho_1954

Organism
Owenweeksia hongkongensis (strain DSM 17368 / JCM 12287 / NRRL B-23963)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Cofactori

pyridoxal 5'-phosphateSAAS annotation

GO - Molecular functioni

  1. alanine racemase activity Source: InterPro
  2. ATP binding Source: InterPro
  3. UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity Source: InterPro

GO - Biological processi

  1. alanine metabolic process Source: InterPro
  2. biosynthetic process Source: InterPro
  3. cell division Source: InterPro
  4. regulation of cell shape Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateSAAS annotation

Enzyme and pathway databases

BioCyciOHON926562:GHWV-1953-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Alanine racemaseImported
Gene namesi
Ordered Locus Names:Oweho_1954Imported
OrganismiOwenweeksia hongkongensis (strain DSM 17368 / JCM 12287 / NRRL B-23963)Imported
Taxonomic identifieri926562 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesCryomorphaceaeOwenweeksia
ProteomesiUP000005631: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliG8R2E3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK01775.
OMAiEPEIYSF.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
3.40.1190.10. 1 hit.
3.40.1390.10. 1 hit.
3.90.190.20. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
IPR000713. Mur_ligase_N.
IPR029066. PLP-binding_barrel.
IPR005863. UDP-N-AcMur-pentapeptide_synth.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
PF01225. Mur_ligase. 1 hit.
PF02875. Mur_ligase_C. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
SSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
SSF63418. SSF63418. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
TIGR01143. murF. 1 hit.

Sequencei

Sequence statusi: Complete.

G8R2E3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQLAISKIA ELLNAEFSAL YPSEIVTRIL LDSRQFSSAE GVLFFALRGK
60 70 80 90 100
NHDGHKYIED LVKKGVSHFV VEQMPTQTFD ANFVVVPDSL KALQDLAKHI
110 120 130 140 150
REQSSAAVIA VTGSNGKTVV KEWMGQILQK QFSTCRSPKS YNSQIGVPLS
160 170 180 190 200
VWELEAKNEF AVFESGISEP DEMEKLEKIL QPEIGIFTNI GSAHDANFES
210 220 230 240 250
NSEKIAEKLK LFKHSKQLVY EANGSNLAKQ IEVFTEERGI QLLSWTRENG
260 270 280 290 300
PADLRIEVKI EEAQTVLIGT MDERTHTLQI PFTDAASIQN AIHCWRLGLE
310 320 330 340 350
LSLDEEEMKK SFAKLNPVEM RLQMKAGSNG NIIINDAYNS DMESLRVALH
360 370 380 390 400
YLENQAGNRK KVLIISELQQ SGLASEELFS RMAEVINRFE LDEIIAIGKD
410 420 430 440 450
LKNGAFALNS TAIFYPSTKH FLKNIYSHSF KQSAILLKGA RSFHFEEISS
460 470 480 490 500
ALEEKSHQTV LNIYMNRMVY NLNYFRSKLN GGTRIMAMVK AFSYGSGTYE
510 520 530 540 550
IANLLQFHKV DYLGVAYTDE GVALRKAGIS LPILVLNAEP SSFHDLVEYN
560 570 580 590 600
LEPEVYSFHQ LEMLENALKN YNLSEAFKVH LKVETGMHRL GFVEDQLKDL
610 620 630 640 650
AEKLKSHRHI KVASVFSHLA ASDDPEQRDF TLGQVAKLKQ MTDKLKSDLG
660 670 680 690 700
YSFLRHISNS SGISQYPEAH FDMVRLGVGL YGIGSNVEDK KHLNVVSDLM
710 720 730 740 750
ASVSQVKQLK VGDSVGYGRT FVAEKPTTIA VVSIGYADGF RRSLSNGVGE
760 770 780 790 800
VVISGKRYQV VGRVCMDMVM VDVTGSDVAE GDEVEVFGPT ISVYELAQKM
810 820
DTIPYEVLTG ISSRVKRVYF ME
Length:822
Mass (Da):91,953
Last modified:February 22, 2012 - v1
Checksum:i3EFF30795E369B47
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003156 Genomic DNA. Translation: AEV32933.1.
RefSeqiWP_014202287.1. NC_016599.1.
YP_004989578.1. NC_016599.1.

Genome annotation databases

EnsemblBacteriaiAEV32933; AEV32933; Oweho_1954.
GeneIDi11631068.
KEGGioho:Oweho_1954.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003156 Genomic DNA. Translation: AEV32933.1.
RefSeqiWP_014202287.1. NC_016599.1.
YP_004989578.1. NC_016599.1.

3D structure databases

ProteinModelPortaliG8R2E3.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEV32933; AEV32933; Oweho_1954.
GeneIDi11631068.
KEGGioho:Oweho_1954.

Phylogenomic databases

KOiK01775.
OMAiEPEIYSF.

Enzyme and pathway databases

BioCyciOHON926562:GHWV-1953-MONOMER.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
3.40.1190.10. 1 hit.
3.40.1390.10. 1 hit.
3.90.190.20. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
IPR000713. Mur_ligase_N.
IPR029066. PLP-binding_barrel.
IPR005863. UDP-N-AcMur-pentapeptide_synth.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
PF01225. Mur_ligase. 1 hit.
PF02875. Mur_ligase_C. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
SSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
SSF63418. SSF63418. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
TIGR01143. murF. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DSM 17368 / JCM 12287 / NRRL B-23963Imported.

Entry informationi

Entry nameiG8R2E3_OWEHD
AccessioniPrimary (citable) accession number: G8R2E3
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: March 4, 2015
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.