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Protein

2,3-bisphosphoglycerate-dependent phosphoglycerate mutase

Gene

gpmA

Organism
Sphaerochaeta pleomorpha (strain ATCC BAA-1885 / DSM 22778 / Grapes)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.UniRule annotation

Catalytic activityi

2-phospho-D-glycerate = 3-phospho-D-glycerate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei8 – 81Tele-phosphohistidine intermediateUniRule annotation
Binding sitei14 – 1412-phospho-D-glycerateUniRule annotation
Binding sitei59 – 5912-phospho-D-glycerateUniRule annotation
Binding sitei97 – 9712-phospho-D-glycerateUniRule annotation
Active sitei181 – 1811UniRule annotation
Binding sitei183 – 18312-phospho-D-glycerateUniRule annotation

GO - Molecular functioni

  1. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciSPLE158190:GHFO-2305-MONOMER.
UniPathwayiUPA00109; UER00186.

Names & Taxonomyi

Protein namesi
Recommended name:
2,3-bisphosphoglycerate-dependent phosphoglycerate mutaseUniRule annotation (EC:5.4.2.11UniRule annotation)
Short name:
BPG-dependent PGAMUniRule annotation
Short name:
PGAMUniRule annotation
Short name:
PhosphoglyceromutaseUniRule annotation
Short name:
dPGMUniRule annotation
Gene namesi
Name:gpmAUniRule annotation
Ordered Locus Names:SpiGrapes_2305Imported
OrganismiSphaerochaeta pleomorpha (strain ATCC BAA-1885 / DSM 22778 / Grapes)Imported
Taxonomic identifieri158190 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeSphaerochaeta
ProteomesiUP000005632 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliG8QSF1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni20 – 2122-phospho-D-glycerate bindingUniRule annotation
Regioni86 – 8942-phospho-D-glycerate bindingUniRule annotation
Regioni113 – 11422-phospho-D-glycerate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.UniRule annotation

Phylogenomic databases

KOiK01834.
OMAiDRVLPYW.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
HAMAPiMF_01039. PGAM_GpmA.
InterProiIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR001345. PG/BPGM_mutase_AS.
IPR005952. Phosphogly_mut1.
[Graphical view]
PANTHERiPTHR11931. PTHR11931. 1 hit.
PfamiPF00300. His_Phos_1. 1 hit.
[Graphical view]
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
TIGRFAMsiTIGR01258. pgm_1. 1 hit.
PROSITEiPS00175. PG_MUTASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8QSF1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLVLLRHGQ SLWNLENRFT GWTDVPLSEA GRLEASEAGR LLKEEGFDFD
60 70 80 90 100
CCYTSYLKRA IQTLDLVLEQ MDRQWLPVVK SWKLNERHYG ALQGLNKAET
110 120 130 140 150
AVKYGNEQVL LWRRSFSVQP PSLSINDERN PALQNQYRGI DKNVLPFTES
160 170 180 190 200
LKDTIARTIP YFEEEIKPRM LKGERILIVA HGNSLRALVM YFEHLSEDEI
210 220 230 240
MQVNIPTGIP LIYTFSKDFS VKKKYYLGDS GEIAEKMRQV SDQGKATKA
Length:249
Mass (Da):28,720
Last modified:February 22, 2012 - v1
Checksum:i180A3A5A5EDF27B7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003155 Genomic DNA. Translation: AEV30081.1.
RefSeqiYP_005063091.1. NC_016633.1.

Genome annotation databases

EnsemblBacteriaiAEV30081; AEV30081; SpiGrapes_2305.
KEGGisgp:SpiGrapes_2305.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003155 Genomic DNA. Translation: AEV30081.1.
RefSeqiYP_005063091.1. NC_016633.1.

3D structure databases

ProteinModelPortaliG8QSF1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEV30081; AEV30081; SpiGrapes_2305.
KEGGisgp:SpiGrapes_2305.

Phylogenomic databases

KOiK01834.
OMAiDRVLPYW.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00186.
BioCyciSPLE158190:GHFO-2305-MONOMER.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
HAMAPiMF_01039. PGAM_GpmA.
InterProiIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR001345. PG/BPGM_mutase_AS.
IPR005952. Phosphogly_mut1.
[Graphical view]
PANTHERiPTHR11931. PTHR11931. 1 hit.
PfamiPF00300. His_Phos_1. 1 hit.
[Graphical view]
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
TIGRFAMsiTIGR01258. pgm_1. 1 hit.
PROSITEiPS00175. PG_MUTASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1885 / DSM 22778 / GrapesImported.

Entry informationi

Entry nameiG8QSF1_SPHPG
AccessioniPrimary (citable) accession number: G8QSF1
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: April 29, 2015
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.