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G8QPQ7 (G8QPQ7_AZOSU) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyltransferase component of pyruvate dehydrogenase complex RuleBase RU361137

EC=2.3.1.12 RuleBase RU361137
Gene names
Ordered Locus Names:Dsui_1577 EMBL AEV25966.1
OrganismAzospira oryzae (strain ATCC BAA-33 / DSM 13638 / PS) (Dechlorosoma suillum) [Complete proteome] [HAMAP] EMBL AEV25966.1
Taxonomic identifier640081 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeAzospira

Protein attributes

Sequence length555 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2 By similarity. RuleBase RU361137

Catalytic activity

Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine. RuleBase RU361137

Cofactor

Binds 1 lipoyl cofactor covalently By similarity. RuleBase RU361137

Binds 2 lipoyl cofactors covalently By similarity. RuleBase RU361137

Binds 3 lipoyl cofactors covalently By similarity. RuleBase RU361137

Subunit structure

Forms a 24-polypeptide structural core with octahedral symmetry By similarity. RuleBase RU361137

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU361137

Contains 2 lipoyl-binding domains. RuleBase RU361137

Ontologies

Sequences

Sequence LengthMass (Da)Tools
G8QPQ7 [UniParc].

Last modified February 22, 2012. Version 1.
Checksum: 37BFFFD535968CF9

FASTA55557,010
        10         20         30         40         50         60 
MSQTIEVKVP DIGDFKDVPV IEIFVKPGDT VKVEDPLCSL ESDKATMDVP SSAAGVVKEV 

        70         80         90        100        110        120 
KIKVGDKVAE GSVVVILESA ASGAAAAAPA PQAAAPAPVA AAPAAPAPVA AAPAPAASGP 

       130        140        150        160        170        180 
VEVKVPDIGD FKDVPVIEVF VKVGDTVKQE DALCSLESDK ATMDVPSSAA GVVKEVRVKV 

       190        200        210        220        230        240 
GDKVSEGSVV VVLEGAAGAV AAVAAAPAAA APAPAAPAVI PPELDGPAPT KPFTPAPAAA 

       250        260        270        280        290        300 
PYGLALGGKV HASPSVRAFA RELGVDLSKV TATGPKSRIQ AEDVKAYIKG VMSGQTVAPT 

       310        320        330        340        350        360 
QVGGGGITGG GSLDLLPWPK VDFAKFGPIE AKPLSRIKKI SGANLARNWV MIPAVTYHED 

       370        380        390        400        410        420 
ADITDLEAFR VQLNKENEKS GQKLTMLAFI IKACVKVLQQ FPELNTSLDG DNLVYKKYYH 

       430        440        450        460        470        480 
IGFAADTPNG LVVPVLKDAD KKGVLEIAKE TGELAKLARD GKLKPADMQG ATFTISSVGG 

       490        500        510        520        530        540 
IGGTAFSPIV NAPEVAILGV SKSSMKPVWN GKEFVPRLIV PLSLSADHRV IDGALATRFN 

       550 
AELAKLLADF RRVML 

« Hide

References

[1]"Complete Genome Sequence of the Anaerobic Perchlorate-Reducing Bacterium Azospira suillum Strain PS."
Byrne-Bailey K.G., Coates J.D.
J. Bacteriol. 194:2767-2768(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-33 / DSM 13638 / PS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003153 Genomic DNA. Translation: AEV25966.1.
RefSeqYP_005027807.1. NC_016616.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEV25966; AEV25966; Dsui_1577.
GeneID11544488.
KEGGdsu:Dsui_1577.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00627.

Enzyme and pathway databases

BioCycAORY640081:GHAS-1577-MONOMER.

Family and domain databases

Gene3D3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR006256. AcTrfase_Pyrv_DH_cplx.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 2 hits.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 2 hits.
TIGRFAMsTIGR01348. PDHac_trf_long. 1 hit.
PROSITEPS50968. BIOTINYL_LIPOYL. 2 hits.
PS00189. LIPOYL. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG8QPQ7_AZOSU
AccessionPrimary (citable) accession number: G8QPQ7
Entry history
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: July 9, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)