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Protein

Isocitrate dehydrogenase [NADP]

Gene

Dsui_3296

Organism
Dechlorosoma suillum (strain ATCC BAA-33 / DSM 13638 / PS) (Azospira oryzae)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Mg2+UniRule annotation, Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciAORY640081:GHAS-3295-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Ordered Locus Names:Dsui_3296Imported
OrganismiDechlorosoma suillum (strain ATCC BAA-33 / DSM 13638 / PS) (Azospira oryzae)Imported
Taxonomic identifieri640081 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeAzospira
Proteomesi
  • UP000005633 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi640081.Dsui_3296.

Structurei

3D structure databases

ProteinModelPortaliG8QJF8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini25 – 404380Iso_dhInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108HMX. Bacteria.
COG0538. LUCA.
KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 2 hits.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
SMARTiSM01329. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8QJF8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSHIKVPQG GQKIIPGQPT PNHPIIPFIE GDGIGVDITP VMIKVVDAAV
60 70 80 90 100
QKAYGGQKKI HWMEVYAGEK STRIYGADEW LPKETFDALK EYSVSIKGPM
110 120 130 140 150
TTPVGGGIRS LNVALRQELD LYQCVRPVQY FKGVPSPLKQ PELCNMVIFR
160 170 180 190 200
ENTEDIYAGI EWAHGSEACK KVIKFLQEEM GVKKIRFPES SGIGIKPISV
210 220 230 240 250
EGTERLVRAA IKYAIDNGRK SVTIVHKGNI MKFTEGNFRD TAYALAKREF
260 270 280 290 300
GGVDIDGGPW QKLPNGIVIK DAIADAFLQQ ILLRPAEYDV IATTNLNGDY
310 320 330 340 350
ISDALAAQVG GIGIAPGANI SDQYACFEAT HGTAPKYAGK DKVNPGSLIL
360 370 380 390 400
SAEMMLRHLG WKEAADLIIK SMEAAIGDKV VTYDFARLME GATEVSCSEF

GEAMIARM
Length:408
Mass (Da):44,493
Last modified:February 22, 2012 - v1
Checksum:i8A8418A298F491FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003153 Genomic DNA. Translation: AEV27627.1.
RefSeqiWP_014238307.1. NC_016616.1.

Genome annotation databases

EnsemblBacteriaiAEV27627; AEV27627; Dsui_3296.
KEGGidsu:Dsui_3296.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003153 Genomic DNA. Translation: AEV27627.1.
RefSeqiWP_014238307.1. NC_016616.1.

3D structure databases

ProteinModelPortaliG8QJF8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi640081.Dsui_3296.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEV27627; AEV27627; Dsui_3296.
KEGGidsu:Dsui_3296.

Phylogenomic databases

eggNOGiENOG4108HMX. Bacteria.
COG0538. LUCA.
KOiK00031.

Enzyme and pathway databases

BioCyciAORY640081:GHAS-3295-MONOMER.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 2 hits.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
SMARTiSM01329. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the anaerobic perchlorate-reducing bacterium Azospira suillum strain PS."
    Byrne-Bailey K.G., Coates J.D.
    J. Bacteriol. 194:2767-2768(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-33 / DSM 13638 / PSImported.

Entry informationi

Entry nameiG8QJF8_DECSP
AccessioniPrimary (citable) accession number: G8QJF8
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: June 8, 2016
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.