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G8Q8P2

- G8Q8P2_PSEFL

UniProt

G8Q8P2 - G8Q8P2_PSEFL

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Protein

Isocitrate dehydrogenase [NADP]

Gene
icd, PSF113_2169
Organism
Pseudomonas fluorescens F113
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciPFLU1114970:GJXA-2189-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Name:icdImported
ORF Names:PSF113_2169Imported
OrganismiPseudomonas fluorescens F113Imported
Taxonomic identifieri1114970 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000005437: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiG8Q8P2.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8Q8P2-1 [UniParc]FASTAAdd to Basket

« Hide

MGYQKIQVPA VGDKITVNAD HSLNVPDNPI IPFIEGDGIG VDISPVMIKV    50
VDAAVQKAYG GKRKISWMEV YAGEKATQVY DQDTWLPQET LDAVKDYVVS 100
IKGPLTTPVG GGIRSLNVAL RQQLDLYVCL RPVRWFEGVP SPVKKPGDVD 150
MTIFRENSED IYAGIEWKAG SAEATKVIKF LKEEMGVTKI RFDEDCGIGI 200
KPVSKQGTQR LARKALQYVV DNDRESLTIV HKGNIMKFTE GAFKEWAYEV 250
AAEEFGATLL DGGPWMQFKN PKTGKNVVVK DAIADAMLQQ ILLRPAEYDV 300
IATLNLNGDY LSDALAAEVG GIGIAPGANL SDTVAMFEAT HGTAPKYAGK 350
DQVNPGSLIL SAEMMLRHMG WTEAADLIIK GTNGAISAKT VTYDFERLME 400
GAKLVSSSGF GDALISHM 418
Length:418
Mass (Da):45,404
Last modified:February 22, 2012 - v1
Checksum:i39EA8672D4FFA9CC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003150 Genomic DNA. Translation: AEV62180.1.
RefSeqiYP_005207575.1. NC_016830.1.

Genome annotation databases

EnsemblBacteriaiAEV62180; AEV62180; PSF113_2169.
GeneIDi11830262.
KEGGipfe:PSF113_2169.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003150 Genomic DNA. Translation: AEV62180.1 .
RefSeqi YP_005207575.1. NC_016830.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi G8Q8P2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEV62180 ; AEV62180 ; PSF113_2169 .
GeneIDi 11830262.
KEGGi pfe:PSF113_2169.

Phylogenomic databases

KOi K00031.

Enzyme and pathway databases

BioCyci PFLU1114970:GJXA-2189-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: F113Imported.

Entry informationi

Entry nameiG8Q8P2_PSEFL
AccessioniPrimary (citable) accession number: G8Q8P2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 3, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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