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G8Q8P2

- G8Q8P2_PSEFL

UniProt

G8Q8P2 - G8Q8P2_PSEFL

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Protein

Isocitrate dehydrogenase [NADP]

Gene

icd

Organism
Pseudomonas fluorescens F113
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Binds 1 magnesium or manganese ion per subunit.UniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciPFLU1114970:GJXA-2189-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Name:icdImported
ORF Names:PSF113_2169Imported
OrganismiPseudomonas fluorescens F113Imported
Taxonomic identifieri1114970 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000005437: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiG8Q8P2.

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8Q8P2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGYQKIQVPA VGDKITVNAD HSLNVPDNPI IPFIEGDGIG VDISPVMIKV
60 70 80 90 100
VDAAVQKAYG GKRKISWMEV YAGEKATQVY DQDTWLPQET LDAVKDYVVS
110 120 130 140 150
IKGPLTTPVG GGIRSLNVAL RQQLDLYVCL RPVRWFEGVP SPVKKPGDVD
160 170 180 190 200
MTIFRENSED IYAGIEWKAG SAEATKVIKF LKEEMGVTKI RFDEDCGIGI
210 220 230 240 250
KPVSKQGTQR LARKALQYVV DNDRESLTIV HKGNIMKFTE GAFKEWAYEV
260 270 280 290 300
AAEEFGATLL DGGPWMQFKN PKTGKNVVVK DAIADAMLQQ ILLRPAEYDV
310 320 330 340 350
IATLNLNGDY LSDALAAEVG GIGIAPGANL SDTVAMFEAT HGTAPKYAGK
360 370 380 390 400
DQVNPGSLIL SAEMMLRHMG WTEAADLIIK GTNGAISAKT VTYDFERLME
410
GAKLVSSSGF GDALISHM
Length:418
Mass (Da):45,404
Last modified:February 22, 2012 - v1
Checksum:i39EA8672D4FFA9CC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003150 Genomic DNA. Translation: AEV62180.1.
RefSeqiWP_014337687.1. NC_016830.1.
YP_005207575.1. NC_016830.1.

Genome annotation databases

EnsemblBacteriaiAEV62180; AEV62180; PSF113_2169.
GeneIDi11830262.
KEGGipfe:PSF113_2169.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003150 Genomic DNA. Translation: AEV62180.1 .
RefSeqi WP_014337687.1. NC_016830.1.
YP_005207575.1. NC_016830.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi G8Q8P2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEV62180 ; AEV62180 ; PSF113_2169 .
GeneIDi 11830262.
KEGGi pfe:PSF113_2169.

Phylogenomic databases

KOi K00031.

Enzyme and pathway databases

BioCyci PFLU1114970:GJXA-2189-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: F113Imported.

Entry informationi

Entry nameiG8Q8P2_PSEFL
AccessioniPrimary (citable) accession number: G8Q8P2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: October 29, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3