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G8Q8P2 (G8Q8P2_PSEFL) Unreviewed, UniProtKB/TrEMBL

Last modified January 22, 2014. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Name:icd EMBL AEV62180.1
ORF Names:PSF113_2169 EMBL AEV62180.1
OrganismPseudomonas fluorescens F113 [Complete proteome] EMBL AEV62180.1
Taxonomic identifier1114970 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length418 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
G8Q8P2 [UniParc].

Last modified February 22, 2012. Version 1.
Checksum: 39EA8672D4FFA9CC

FASTA41845,404
        10         20         30         40         50         60 
MGYQKIQVPA VGDKITVNAD HSLNVPDNPI IPFIEGDGIG VDISPVMIKV VDAAVQKAYG 

        70         80         90        100        110        120 
GKRKISWMEV YAGEKATQVY DQDTWLPQET LDAVKDYVVS IKGPLTTPVG GGIRSLNVAL 

       130        140        150        160        170        180 
RQQLDLYVCL RPVRWFEGVP SPVKKPGDVD MTIFRENSED IYAGIEWKAG SAEATKVIKF 

       190        200        210        220        230        240 
LKEEMGVTKI RFDEDCGIGI KPVSKQGTQR LARKALQYVV DNDRESLTIV HKGNIMKFTE 

       250        260        270        280        290        300 
GAFKEWAYEV AAEEFGATLL DGGPWMQFKN PKTGKNVVVK DAIADAMLQQ ILLRPAEYDV 

       310        320        330        340        350        360 
IATLNLNGDY LSDALAAEVG GIGIAPGANL SDTVAMFEAT HGTAPKYAGK DQVNPGSLIL 

       370        380        390        400        410 
SAEMMLRHMG WTEAADLIIK GTNGAISAKT VTYDFERLME GAKLVSSSGF GDALISHM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003150 Genomic DNA. Translation: AEV62180.1.
RefSeqYP_005207575.1. NC_016830.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEG8Q8P2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEV62180; AEV62180; PSF113_2169.
GeneID11830262.
KEGGpfe:PSF113_2169.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00031.

Enzyme and pathway databases

BioCycPFLU1114970:GJXA-2189-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG8Q8P2_PSEFL
AccessionPrimary (citable) accession number: G8Q8P2
Entry history
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: January 22, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)