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G8Q8P2

- G8Q8P2_PSEFL

UniProt

G8Q8P2 - G8Q8P2_PSEFL

Protein

Isocitrate dehydrogenase [NADP]

Gene

icd

Organism
Pseudomonas fluorescens F113
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (22 Feb 2012)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. magnesium ion binding Source: InterPro
    3. NAD binding Source: InterPro

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-KW
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotationImported

    Keywords - Biological processi

    Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

    Keywords - Ligandi

    ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

    Enzyme and pathway databases

    BioCyciPFLU1114970:GJXA-2189-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
    Gene namesi
    Name:icdImported
    ORF Names:PSF113_2169Imported
    OrganismiPseudomonas fluorescens F113Imported
    Taxonomic identifieri1114970 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000005437: Chromosome

    PTM / Processingi

    Proteomic databases

    PRIDEiG8Q8P2.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

    Phylogenomic databases

    KOiK00031.

    Family and domain databases

    Gene3Di3.40.718.10. 1 hit.
    InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PANTHERiPTHR11835. PTHR11835. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
    PROSITEiPS00470. IDH_IMDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G8Q8P2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGYQKIQVPA VGDKITVNAD HSLNVPDNPI IPFIEGDGIG VDISPVMIKV    50
    VDAAVQKAYG GKRKISWMEV YAGEKATQVY DQDTWLPQET LDAVKDYVVS 100
    IKGPLTTPVG GGIRSLNVAL RQQLDLYVCL RPVRWFEGVP SPVKKPGDVD 150
    MTIFRENSED IYAGIEWKAG SAEATKVIKF LKEEMGVTKI RFDEDCGIGI 200
    KPVSKQGTQR LARKALQYVV DNDRESLTIV HKGNIMKFTE GAFKEWAYEV 250
    AAEEFGATLL DGGPWMQFKN PKTGKNVVVK DAIADAMLQQ ILLRPAEYDV 300
    IATLNLNGDY LSDALAAEVG GIGIAPGANL SDTVAMFEAT HGTAPKYAGK 350
    DQVNPGSLIL SAEMMLRHMG WTEAADLIIK GTNGAISAKT VTYDFERLME 400
    GAKLVSSSGF GDALISHM 418
    Length:418
    Mass (Da):45,404
    Last modified:February 22, 2012 - v1
    Checksum:i39EA8672D4FFA9CC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003150 Genomic DNA. Translation: AEV62180.1.
    RefSeqiYP_005207575.1. NC_016830.1.

    Genome annotation databases

    EnsemblBacteriaiAEV62180; AEV62180; PSF113_2169.
    GeneIDi11830262.
    KEGGipfe:PSF113_2169.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003150 Genomic DNA. Translation: AEV62180.1 .
    RefSeqi YP_005207575.1. NC_016830.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi G8Q8P2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEV62180 ; AEV62180 ; PSF113_2169 .
    GeneIDi 11830262.
    KEGGi pfe:PSF113_2169.

    Phylogenomic databases

    KOi K00031.

    Enzyme and pathway databases

    BioCyci PFLU1114970:GJXA-2189-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 1 hit.
    InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    PANTHERi PTHR11835. PTHR11835. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
    PROSITEi PS00470. IDH_IMDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: F113Imported.

    Entry informationi

    Entry nameiG8Q8P2_PSEFL
    AccessioniPrimary (citable) accession number: G8Q8P2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 22, 2012
    Last sequence update: February 22, 2012
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3