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Protein

Isocitrate dehydrogenase [NADP]

Gene

icd

Organism
Pseudomonas fluorescens F113
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Mg2+UniRule annotation, Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseImported
Biological processGlyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation
LigandManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciPFLU1114970:G1H1T-2276-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Name:icdImported
ORF Names:PSF113_2169Imported
OrganismiPseudomonas fluorescens F113Imported
Taxonomic identifieri1114970 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000005437 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi1114970.PSF113_2169

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 414Iso_dhInterPro annotationAdd BLAST385

Phylogenomic databases

eggNOGiENOG4108HMX Bacteria
COG0538 LUCA
KOiK00031

Family and domain databases

InterProiView protein in InterPro
IPR019818 IsoCit/isopropylmalate_DH_CS
IPR004439 Isocitrate_DH_NADP_dimer_prok
IPR024084 IsoPropMal-DH-like_dom
PANTHERiPTHR43504 PTHR43504, 1 hit
PfamiView protein in Pfam
PF00180 Iso_dh, 1 hit
SMARTiView protein in SMART
SM01329 Iso_dh, 1 hit
TIGRFAMsiTIGR00183 prok_nadp_idh, 1 hit
PROSITEiView protein in PROSITE
PS00470 IDH_IMDH, 1 hit

Sequencei

Sequence statusi: Complete.

G8Q8P2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGYQKIQVPA VGDKITVNAD HSLNVPDNPI IPFIEGDGIG VDISPVMIKV
60 70 80 90 100
VDAAVQKAYG GKRKISWMEV YAGEKATQVY DQDTWLPQET LDAVKDYVVS
110 120 130 140 150
IKGPLTTPVG GGIRSLNVAL RQQLDLYVCL RPVRWFEGVP SPVKKPGDVD
160 170 180 190 200
MTIFRENSED IYAGIEWKAG SAEATKVIKF LKEEMGVTKI RFDEDCGIGI
210 220 230 240 250
KPVSKQGTQR LARKALQYVV DNDRESLTIV HKGNIMKFTE GAFKEWAYEV
260 270 280 290 300
AAEEFGATLL DGGPWMQFKN PKTGKNVVVK DAIADAMLQQ ILLRPAEYDV
310 320 330 340 350
IATLNLNGDY LSDALAAEVG GIGIAPGANL SDTVAMFEAT HGTAPKYAGK
360 370 380 390 400
DQVNPGSLIL SAEMMLRHMG WTEAADLIIK GTNGAISAKT VTYDFERLME
410
GAKLVSSSGF GDALISHM
Length:418
Mass (Da):45,404
Last modified:February 22, 2012 - v1
Checksum:i39EA8672D4FFA9CC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003150 Genomic DNA Translation: AEV62180.1
RefSeqiWP_014337687.1, NC_016830.1

Genome annotation databases

EnsemblBacteriaiAEV62180; AEV62180; PSF113_2169
GeneIDi11830262
KEGGipfe:PSF113_2169
PATRICifig|1114970.3.peg.2199

Similar proteinsi

Entry informationi

Entry nameiG8Q8P2_PSEFL
AccessioniPrimary (citable) accession number: G8Q8P2
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: May 23, 2018
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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