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Protein

Alanine racemase

Gene

dadB

Organism
Pseudovibrio sp. (strain FO-BEG1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Pathwayi: D-alanine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes D-alanine from L-alanine.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Alanine racemase (dadB), Alanine racemase (PSE_3114)
This subpathway is part of the pathway D-alanine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-alanine from L-alanine, the pathway D-alanine biosynthesis and in Amino-acid biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei51Proton acceptor; specific for D-alanineUniRule annotation1
Binding sitei149SubstrateUniRule annotation1
Active sitei271Proton acceptor; specific for L-alanineUniRule annotation1
Binding sitei325Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
LigandPyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00042; UER00497

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:dadBImported
Ordered Locus Names:PSE_2712Imported
OrganismiPseudovibrio sp. (strain FO-BEG1)Imported
Taxonomic identifieri911045 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaePseudovibrio
Proteomesi

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei51N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi911045.PSE_2712

Structurei

3D structure databases

ProteinModelPortaliG8PQX4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini250 – 382Ala_racemase_CInterPro annotationAdd BLAST133

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ4 Bacteria
COG0787 LUCA
KOiK01775
OMAiCALHVDT
OrthoDBiPOG091H022F

Family and domain databases

Gene3Di2.40.37.10, 1 hit
3.20.20.10, 1 hit
HAMAPiMF_01201 Ala_racemase, 1 hit
InterProiView protein in InterPro
IPR000821 Ala_racemase
IPR009006 Ala_racemase/Decarboxylase_C
IPR011079 Ala_racemase_C
IPR001608 Ala_racemase_N
IPR029066 PLP-binding_barrel
PfamiView protein in Pfam
PF00842 Ala_racemase_C, 1 hit
PF01168 Ala_racemase_N, 1 hit
PRINTSiPR00992 ALARACEMASE
SMARTiView protein in SMART
SM01005 Ala_racemase_C, 1 hit
SUPFAMiSSF50621 SSF50621, 1 hit
SSF51419 SSF51419, 1 hit
TIGRFAMsiTIGR00492 alr, 1 hit

Sequencei

Sequence statusi: Complete.

G8PQX4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHSAAPTSD RPAVSAGGAA KLTIDLTALR SNWCYLNGKV GDGCTCAVVL
60 70 80 90 100
KANGYGTGAA EVGKTLYHAG ARVFFVALPE EGIELRKELP HAEIYVLNGL
110 120 130 140 150
FRDREKFYYD FDLKPVLNSL EEVAEWSSFA QSLQEELPAA LHFDTGMHRL
160 170 180 190 200
GMSIGDALQI GESAHLLKGI RIDLVMSHLA CADTPGHGLN EKQLNRFQRV
210 220 230 240 250
CELFPEARKS LSNSAGIFLG DDYHFDMVRP GIALYGGNPV PDETNPMLPV
260 270 280 290 300
AHVQAEIISL REVPHGDPVG YGASRVTPRK SRIATINAGY ADGLHRLVGS
310 320 330 340 350
SDDQPNGARV YIGGHFAPIF GRVSMDMIAV DVTDIPEEHL SRGAPVEIMG
360 370 380
AHVNVDELAE FAQTIPYELL CSLGARYTRH YKR
Length:383
Mass (Da):41,680
Last modified:February 22, 2012 - v1
Checksum:i6F91441482FBBAE2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003147 Genomic DNA Translation: AEV37220.1
RefSeqiWP_014285320.1, NC_016642.1

Genome annotation databases

EnsemblBacteriaiAEV37220; AEV37220; PSE_2712
KEGGipsf:PSE_2712

Similar proteinsi

Entry informationi

Entry nameiG8PQX4_PSEUV
AccessioniPrimary (citable) accession number: G8PQX4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: March 28, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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