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G8PMX1

- G8PMX1_PSEUV

UniProt

G8PMX1 - G8PMX1_PSEUV

Protein

Malate dehydrogenase

Gene

mdh

Organism
Pseudovibrio sp. (strain FO-BEG1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 14 (01 Oct 2014)
      Sequence version 1 (22 Feb 2012)
      Previous versions | rss
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    Functioni

    Catalyzes the reversible oxidation of malate to oxaloacetate.UniRule annotationSAAS annotation

    Catalytic activityi

    (S)-malate + NAD+ = oxaloacetate + NADH.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei34 – 341NADUniRule annotation
    Binding sitei83 – 831SubstrateUniRule annotation
    Binding sitei89 – 891SubstrateUniRule annotation
    Binding sitei96 – 961NADUniRule annotation
    Binding sitei121 – 1211SubstrateUniRule annotation
    Binding sitei152 – 1521SubstrateUniRule annotation
    Active sitei176 – 1761Proton acceptorUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi10 – 156NADUniRule annotation
    Nucleotide bindingi119 – 1213NADUniRule annotation

    GO - Molecular functioni

    1. L-malate dehydrogenase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. cellular carbohydrate metabolic process Source: InterPro
    2. malate metabolic process Source: InterPro
    3. tricarboxylic acid cycle Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Tricarboxylic acid cycleUniRule annotationSAAS annotation

    Keywords - Ligandi

    NADUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciPSP911045:GJTQ-618-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Malate dehydrogenaseUniRule annotation (EC:1.1.1.37UniRule annotation)
    Gene namesi
    Name:mdhUniRule annotationImported
    Ordered Locus Names:PSE_0614Imported
    OrganismiPseudovibrio sp. (strain FO-BEG1)Imported
    Taxonomic identifieri911045 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaePseudovibrio
    ProteomesiUP000005634: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliG8PMX1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the LDH/MDH superfamily. MDH type 3 family.UniRule annotation

    Phylogenomic databases

    KOiK00024.
    OMAiDANIVEC.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    3.90.110.10. 1 hit.
    HAMAPiMF_00487. Malate_dehydrog_3.
    InterProiIPR001557. L-lactate/malate_DH.
    IPR022383. Lactate/malate_DH_C.
    IPR001236. Lactate/malate_DH_N.
    IPR015955. Lactate_DH/Glyco_Ohase_4_C.
    IPR011275. Malate_DH_type3.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PANTHERiPTHR11540. PTHR11540. 1 hit.
    PfamiPF02866. Ldh_1_C. 1 hit.
    PF00056. Ldh_1_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000102. Lac_mal_DH. 1 hit.
    PRINTSiPR00086. LLDHDRGNASE.
    SUPFAMiSSF56327. SSF56327. 1 hit.
    TIGRFAMsiTIGR01763. MalateDH_bact. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    G8PMX1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MARNKIALIG SGQIGGTLAH LAGLKELGDI VLFDIAEGMP QGKALDLAES    50
    SPVDGFDSGL SGTNTYEGIE GADVVIVTAG VPRKPGMSRD DLLEINLKVM 100
    EQVGAGIKKY APDAFVICIT NPLDAMVWAL QKFSGLPANK VVGMAGVLDS 150
    ARFRYFLAEE FNVSVEDVTA FVLGGHGDTM VPLTRYSTVA GVPLTDLVKM 200
    GWLTAERLEE IVQRTRDGGA EIVGLLKTGS AFYAPAASAI QMAESYLKDK 250
    KRVLPCAAHL DGQYGQKDMY VGVPTVIGAN GIERIIEIDL NSDEKAMFDK 300
    SVASVNGLVD ACKKIQPALA 320
    Length:320
    Mass (Da):33,893
    Last modified:February 22, 2012 - v1
    Checksum:iCC3B2B5B88936B7A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003147 Genomic DNA. Translation: AEV35126.1.
    RefSeqiYP_005079148.1. NC_016642.1.

    Genome annotation databases

    EnsemblBacteriaiAEV35126; AEV35126; PSE_0614.
    GeneIDi11588888.
    KEGGipsf:PSE_0614.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003147 Genomic DNA. Translation: AEV35126.1 .
    RefSeqi YP_005079148.1. NC_016642.1.

    3D structure databases

    ProteinModelPortali G8PMX1.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEV35126 ; AEV35126 ; PSE_0614 .
    GeneIDi 11588888.
    KEGGi psf:PSE_0614.

    Phylogenomic databases

    KOi K00024.
    OMAi DANIVEC.

    Enzyme and pathway databases

    BioCyci PSP911045:GJTQ-618-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    3.90.110.10. 1 hit.
    HAMAPi MF_00487. Malate_dehydrog_3.
    InterProi IPR001557. L-lactate/malate_DH.
    IPR022383. Lactate/malate_DH_C.
    IPR001236. Lactate/malate_DH_N.
    IPR015955. Lactate_DH/Glyco_Ohase_4_C.
    IPR011275. Malate_DH_type3.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    PANTHERi PTHR11540. PTHR11540. 1 hit.
    Pfami PF02866. Ldh_1_C. 1 hit.
    PF00056. Ldh_1_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000102. Lac_mal_DH. 1 hit.
    PRINTSi PR00086. LLDHDRGNASE.
    SUPFAMi SSF56327. SSF56327. 1 hit.
    TIGRFAMsi TIGR01763. MalateDH_bact. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genus Pseudovibrio contains metabolically versatile and symbiotically interacting bacteria."
      Bondarev V., Richter M., Piel J., Schwedt A., Schulz-Vogt H.N.
      Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: FO-BEG1Imported.

    Entry informationi

    Entry nameiG8PMX1_PSEUV
    AccessioniPrimary (citable) accession number: G8PMX1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 22, 2012
    Last sequence update: February 22, 2012
    Last modified: October 1, 2014
    This is version 14 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3