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Protein

Xylose isomerase

Gene

xylA

Organism
Lactococcus lactis subsp. cremoris A76
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei101UniRule annotation1
Active sitei104UniRule annotation1
Metal bindingi232Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 2UniRule annotation1
Metal bindingi271Magnesium 2UniRule annotation1
Metal bindingi296Magnesium 1UniRule annotation1
Metal bindingi307Magnesium 2UniRule annotation1
Metal bindingi309Magnesium 2UniRule annotation1
Metal bindingi339Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processCarbohydrate metabolism, Xylose metabolismUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciLLAC1104322:G1H1N-973-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotation
ORF Names:llh_5060Imported
OrganismiLactococcus lactis subsp. cremoris A76Imported
Taxonomic identifieri1104322 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus
Proteomesi
  • UP000007114 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliG8P8X4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK01805
OrthoDBiPOG091H07LC

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

G8P8X4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYFNDIAPI KYEGTKTKNM FAFRHYNPEE VVAGKTMEEQ LHFALAFWHT
60 70 80 90 100
ITMDGADPFG SATMERPWDL EGGSELDRAH RRVDAFFEIA EKLGVKYYCF
110 120 130 140 150
HDIDIAPTGN SLKEFYANLD EITDHLLEKQ KETGIKLLWN TANMFSNPRY
160 170 180 190 200
MNGVSTSNRA EVFAYGAAQV KKGLELSKKL GGENYVFWGG REGYESLLNT
210 220 230 240 250
DMGLEMDHMA KFFHLAIDYA KSINHLPIFL IELKPKEPMT HQYDFDAATA
260 270 280 290 300
LAFLQKYDLD KYFKLNIETN HAWLAGHTFE HELNTARTFG ALGSIDANQG
310 320 330 340 350
NYLLGWDTDE FPTLVIDITL AMHQILLNGG LGKGGINFDA KVRRTSFKAE
360 370 380 390 400
DLILAHIAGM DTYARALKGA AAIIEDKFLS DIVEERYSSY KKTEVGQSIE
410 420 430
NGTATFESLA AYALEHGDDI ELDSNHLEYI KSVLNDYLV
Length:439
Mass (Da):49,626
Last modified:February 22, 2012 - v1
Checksum:iF686999CAA26EBF4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003132 Genomic DNA Translation: AEU40188.1
RefSeqiWP_014572399.1, NC_017492.1

Genome annotation databases

EnsemblBacteriaiAEU40188; AEU40188; llh_5060
KEGGillr:llh_5060
PATRICifig|1104322.3.peg.1014

Similar proteinsi

Entry informationi

Entry nameiG8P8X4_LACLC
AccessioniPrimary (citable) accession number: G8P8X4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: April 25, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health