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G8P8X4

- G8P8X4_LACLC

UniProt

G8P8X4 - G8P8X4_LACLC

Protein

Xylose isomerase

Gene

xylA

Organism
Lactococcus lactis subsp. cremoris A76
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 20 (01 Oct 2014)
      Sequence version 1 (22 Feb 2012)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

    Cofactori

    Binds 2 magnesium ions per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei101 – 1011UniRule annotation
    Active sitei104 – 1041UniRule annotation
    Metal bindingi232 – 2321Magnesium 1UniRule annotation
    Metal bindingi268 – 2681Magnesium 1UniRule annotation
    Metal bindingi268 – 2681Magnesium 2UniRule annotation
    Metal bindingi271 – 2711Magnesium 2UniRule annotation
    Metal bindingi296 – 2961Magnesium 1UniRule annotation
    Metal bindingi307 – 3071Magnesium 2UniRule annotation
    Metal bindingi309 – 3091Magnesium 2UniRule annotation
    Metal bindingi339 – 3391Magnesium 1UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. xylose isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-xylose metabolic process Source: UniProtKB-HAMAP
    2. pentose-phosphate shunt Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotation, Xylose metabolismUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciLLAC1104322:GLFE-1032-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
    Gene namesi
    Name:xylAUniRule annotation
    ORF Names:llh_5060Imported
    OrganismiLactococcus lactis subsp. cremoris A76Imported
    Taxonomic identifieri1104322 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus
    ProteomesiUP000007114: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotationSAAS annotation

    Structurei

    3D structure databases

    ProteinModelPortaliG8P8X4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the xylose isomerase family.UniRule annotation

    Phylogenomic databases

    KOiK01805.

    Family and domain databases

    Gene3Di3.20.20.150. 1 hit.
    HAMAPiMF_00455. Xylose_isom_A.
    InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013452. Xylose_isom_bac.
    IPR001998. Xylose_isomerase.
    [Graphical view]
    PfamiPF01261. AP_endonuc_2. 1 hit.
    [Graphical view]
    PRINTSiPR00688. XYLOSISMRASE.
    SUPFAMiSSF51658. SSF51658. 1 hit.
    TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
    PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G8P8X4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAYFNDIAPI KYEGTKTKNM FAFRHYNPEE VVAGKTMEEQ LHFALAFWHT    50
    ITMDGADPFG SATMERPWDL EGGSELDRAH RRVDAFFEIA EKLGVKYYCF 100
    HDIDIAPTGN SLKEFYANLD EITDHLLEKQ KETGIKLLWN TANMFSNPRY 150
    MNGVSTSNRA EVFAYGAAQV KKGLELSKKL GGENYVFWGG REGYESLLNT 200
    DMGLEMDHMA KFFHLAIDYA KSINHLPIFL IELKPKEPMT HQYDFDAATA 250
    LAFLQKYDLD KYFKLNIETN HAWLAGHTFE HELNTARTFG ALGSIDANQG 300
    NYLLGWDTDE FPTLVIDITL AMHQILLNGG LGKGGINFDA KVRRTSFKAE 350
    DLILAHIAGM DTYARALKGA AAIIEDKFLS DIVEERYSSY KKTEVGQSIE 400
    NGTATFESLA AYALEHGDDI ELDSNHLEYI KSVLNDYLV 439
    Length:439
    Mass (Da):49,626
    Last modified:February 22, 2012 - v1
    Checksum:iF686999CAA26EBF4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003132 Genomic DNA. Translation: AEU40188.1.
    RefSeqiWP_014572399.1. NC_017492.1.
    YP_005875611.1. NC_017492.1.

    Genome annotation databases

    EnsemblBacteriaiAEU40188; AEU40188; llh_5060.
    GeneIDi12484588.
    KEGGillr:llh_5060.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003132 Genomic DNA. Translation: AEU40188.1 .
    RefSeqi WP_014572399.1. NC_017492.1.
    YP_005875611.1. NC_017492.1.

    3D structure databases

    ProteinModelPortali G8P8X4.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEU40188 ; AEU40188 ; llh_5060 .
    GeneIDi 12484588.
    KEGGi llr:llh_5060.

    Phylogenomic databases

    KOi K01805.

    Enzyme and pathway databases

    BioCyci LLAC1104322:GLFE-1032-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.150. 1 hit.
    HAMAPi MF_00455. Xylose_isom_A.
    InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013452. Xylose_isom_bac.
    IPR001998. Xylose_isomerase.
    [Graphical view ]
    Pfami PF01261. AP_endonuc_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00688. XYLOSISMRASE.
    SUPFAMi SSF51658. SSF51658. 1 hit.
    TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
    PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete Genome Sequence of Lactococcus lactis subsp. cremoris A76."
      Bolotin A., Quinquis B., Ehrlich S.D., Sorokin A.
      Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: A76Imported.

    Entry informationi

    Entry nameiG8P8X4_LACLC
    AccessioniPrimary (citable) accession number: G8P8X4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 22, 2012
    Last sequence update: February 22, 2012
    Last modified: October 1, 2014
    This is version 20 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3