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G8NYX7 (G8NYX7_GRAMM) Unreviewed, UniProtKB/TrEMBL

Last modified October 16, 2013. Version 11. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length467 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity.

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
G8NYX7 [UniParc].

Last modified February 22, 2012. Version 1.
Checksum: 1639DD4FA8D86935

FASTA46751,555
        10         20         30         40         50         60 
MQTSYNDIPV PSDGQAIEYA NGKYTVPDHP IIPFIEGDGT GRDIWKASQR VFDAAVEKAY 

        70         80         90        100        110        120 
GGKRSVKWFE VLAGEKSYRK TQNWLPDDTV KATVDFRVSI KGPLTTPVGG GIRSLNVALR 

       130        140        150        160        170        180 
QLMDLYQCVR PVKYYSGVPS PVKSPEKLDV VIFRENTEDI YAGIEFREGT PEAAKFIAFV 

       190        200        210        220        230        240 
NDEMLKGTKK KVRLDSGVGV KPISITGSKR LVRAAIQYAI DHQRKTVTLV HKGNIQKFTE 

       250        260        270        280        290        300 
GAFREWGYEV ATQEFRAHTV TERESWILGN LEQNPKLTPE ENAALVEPGI EFASKEFGES 

       310        320        330        340        350        360 
IVQEVRDVVA SIGATHGNGQ WKNKILVNDR IADSIFQQII IRPSDYSVLA TTNLNGDYIS 

       370        380        390        400        410        420 
DAAAAQVGGL GIAPGANIGD GYAVFEATHG TAPKYADKDV INPGSVMLSG VMMFDFLGWS 

       430        440        450        460 
EAARLIESSM EKTIQQKFVT YDFERQMQGA TKAKTSEFAS RMIENMG 

« Hide

References

[1]"Complete sequence of Granulicella mallensis MP5ACTX8."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Lu M., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Mikhailova N., Pagani I., Rawat S. expand/collapse author list , Mannisto M., Haggblom M., Woyke T.
Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1857 / DSM 23137 / MP5ACTX8.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003130 Genomic DNA. Translation: AEU35629.1.
RefSeqYP_005056659.1. NC_016631.1.

3D structure databases

ProteinModelPortalG8NYX7.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEU35629; AEU35629; AciX8_1286.
GeneID11571735.
KEGGgma:AciX8_1286.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00031.

Enzyme and pathway databases

BioCycGMAL682795:GHBV-1303-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 2 hits.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG8NYX7_GRAMM
AccessionPrimary (citable) accession number: G8NYX7
Entry history
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: October 16, 2013
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)