ID   G8NWY5_GRAMM            Unreviewed;      1115 AA.
AC   G8NWY5;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   RecName: Full=Maltokinase {ECO:0000256|ARBA:ARBA00013882};
DE            EC=2.7.1.175 {ECO:0000256|ARBA:ARBA00011962};
DE            EC=5.4.99.16 {ECO:0000256|ARBA:ARBA00012619};
DE   AltName: Full=Maltose alpha-D-glucosyltransferase {ECO:0000256|ARBA:ARBA00031378};
DE   AltName: Full=Maltose-1-phosphate synthase {ECO:0000256|ARBA:ARBA00031251};
GN   OrderedLocusNames=AciX8_1169 {ECO:0000313|EMBL:AEU35513.1};
OS   Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8).
OC   Bacteria; Acidobacteriota; Terriglobia; Terriglobales; Acidobacteriaceae;
OC   Granulicella.
OX   NCBI_TaxID=682795 {ECO:0000313|EMBL:AEU35513.1, ECO:0000313|Proteomes:UP000007113};
RN   [1] {ECO:0000313|EMBL:AEU35513.1, ECO:0000313|Proteomes:UP000007113}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1857 / DSM 23137 / MP5ACTX8
RC   {ECO:0000313|Proteomes:UP000007113};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Lu M., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Ivanova N., Mikhailova N., Pagani I., Rawat S., Mannisto M.,
RA   Haggblom M., Woyke T.;
RT   "Complete sequence of Granulicella mallensis MP5ACTX8.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-maltose = ADP + alpha-maltose 1-phosphate + H(+);
CC         Xref=Rhea:RHEA:31915, ChEBI:CHEBI:15378, ChEBI:CHEBI:17306,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:63576, ChEBI:CHEBI:456216;
CC         EC=2.7.1.175; Evidence={ECO:0000256|ARBA:ARBA00001537};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-maltose = alpha,alpha-trehalose; Xref=Rhea:RHEA:15145,
CC         ChEBI:CHEBI:16551, ChEBI:CHEBI:17306; EC=5.4.99.16;
CC         Evidence={ECO:0000256|ARBA:ARBA00001595};
CC   -!- SIMILARITY: Belongs to the aminoglycoside phosphotransferase family.
CC       {ECO:0000256|ARBA:ARBA00006219}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family. TreS
CC       subfamily. {ECO:0000256|ARBA:ARBA00005496}.
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DR   EMBL; CP003130; AEU35513.1; -; Genomic_DNA.
DR   RefSeq; WP_014264393.1; NC_016631.1.
DR   AlphaFoldDB; G8NWY5; -.
DR   STRING; 682795.AciX8_1169; -.
DR   KEGG; gma:AciX8_1169; -.
DR   eggNOG; COG0366; Bacteria.
DR   eggNOG; COG3281; Bacteria.
DR   HOGENOM; CLU_007635_1_1_0; -.
DR   OrthoDB; 9805159at2; -.
DR   Proteomes; UP000007113; Chromosome.
DR   GO; GO:0047471; F:maltose alpha-D-glucosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd11334; AmyAc_TreS; 1.
DR   Gene3D; 3.90.1200.10; -; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR040999; Mak_N_cap.
DR   InterPro; IPR032091; Malt_amylase_C.
DR   InterPro; IPR045857; O16G_dom_2.
DR   InterPro; IPR012810; TreS/a-amylase_N.
DR   InterPro; IPR012811; TreS_maltokin_C_dom.
DR   NCBIfam; TIGR02457; TreS_Cterm; 1.
DR   NCBIfam; TIGR02456; treS_nterm; 1.
DR   PANTHER; PTHR10357; ALPHA-AMYLASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR10357:SF219; MALTOSE ALPHA-D-GLUCOSYLTRANSFERASE; 1.
DR   Pfam; PF00128; Alpha-amylase; 1.
DR   Pfam; PF18085; Mak_N_cap; 1.
DR   Pfam; PF16657; Malt_amylase_C; 1.
DR   SMART; SM00642; Aamy; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:AEU35513.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007113}.
FT   DOMAIN          20..419
FT                   /note="Glycosyl hydrolase family 13 catalytic"
FT                   /evidence="ECO:0000259|SMART:SM00642"
SQ   SEQUENCE   1115 AA;  125044 MW;  3C870163B4C9063F CRC64;
     MKKSCSATDP LWYKDAIIYE LHVRAFADSN DDGIGDFQGL ISKLDYLQDL GVTCLWILPF
     FPSPLRDDGY DIADYTSVNP SYGTIADFQQ FLDAAHARNM QVMIELVINH TSDQHPWFQR
     ARHAPKGSPE RDYYVWSDSD QIYKDARIIF TDTEKSNWTW DEEAQQYYWH RFFSHQPDLN
     FDNPAVMEEV LKAMRFWLDM GVDAMRMDAI PYLVERDGTN CENLPETHAA IKAIRAAIDE
     GYENRLVLAE ANQWPADVRP YFGDGDECHM AFHFPLMPRM YMALRQEDRL PITDIMAQTP
     DIPANCQWGL FLRNHDELTL EMVTDDERDY MYMAYSADPR MRVNVGIRRR LAPLLDNNRR
     RIELMNSLLL SFPGTPIMYY GDELGMGDNI YLGDRNGVRT PMQWNSDRNA GFSKAVPARL
     YFPVIMDPIW GYQAINVEAQ LSDPSSLLHW TRNMIALRKL FQVFGRGSLE FLHPSNRKVL
     AYIRDHKYED GASETVLCVA NLSRFAQPVA LDLAQFAGRQ PMEMLGYVAF PEITDQPYTL
     TLAPYSFFWL ELQPAPPKPE APTIESPAEH EALAGIVPNK TQASPTLSIG ILLQGGGHEL
     LQQLLPNYLE QQRWFGSKSR KIRSATVGSS LALANSEYAV TLIDVTYDNG STERYQLPLA
     IAAGDAAETL RKNSPKAILA TLGDASSGSV LYDATASEGF RQALLEMFIT SPKADATLVA
     SHSPAFDPAS LSQTESRVGS AEQSNTSLLF GQTAILKLFR RLQPGENPDV EISRFLTDVA
     HFDRIPAYLG ELHHEADGTT LAFLQAFAAN EGDGWSWFSE ELIRFYESVA NSPQPASYGK
     PASFLVEAEI PLDAQEHAGF SLEAAALIGT RTAQMHLALA TPTDDAAFTA EITAAKDLAL
     DSARIREQVE HTLGALKRNL AAIPDDLVDG AALLLSHRSE LLKRTQSLAA AAPEAFGQRI
     RSHGDYHLGQ LLHVKSDFLI VDFEGEPARP LEERRLKQSP LKDVAGMLRS FSYASRSTLD
     RYTQRRPEHS VTLAGWASLW ENAVSTKFLQ AYRDAIHAAG TQGESLLPKS SQADTMLRAL
     LLEKSLYELL YELNNRPDWL HIPLSGLLAL ARDTA
//