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G8NU73

- G8NU73_GRAMM

UniProt

G8NU73 - G8NU73_GRAMM

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Protein

Alanine racemase

Gene

AciX8_4435

Organism
Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei34 – 341Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei134 – 1341SubstrateUniRule annotation
Active sitei281 – 2811Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei332 – 3321Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciGMAL682795:GHBV-4487-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:AciX8_4435Imported
OrganismiGranulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8)Imported
Taxonomic identifieri682795 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeGranulicella
ProteomesiUP000007113: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei34 – 341N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliG8NU73.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8NU73-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKSWIEISSA RLAENFRAIQ AVAGQGVEAL AVIKANAYGH GTTICAPVLA
60 70 80 90 100
EAGAQWLGVS DVAEGEAVRT ALPHSGIRVL VMCGMELADA PALVAHGLTP
110 120 130 140 150
VVWTPEHIAA LERAARSAGH RIQVHLEVDT GMGRQGAAPG EDLARTLEAL
160 170 180 190 200
ADSRWVSCEG IMTHLCCSES AEAKITEEQR ERFASALDQA LAAGMRPEFV
210 220 230 240 250
HLANTSAVDE GSTMQWIRDT AKSLGARAMV RIGFAIYGHC LEIEGEHAHA
260 270 280 290 300
GALAPKVSPV LVWKTRIIGL RGVAAGATVG YGATFVATQP MRLALLPVGY
310 320 330 340 350
ADGYRRAASS GVGNGWVMIA GRRAPVVGRV SMNLTVVDVS GHADVQEGME
360 370 380
AVLLGEGVTA EDQARWSGTI AYDILCGIRA NFELR
Length:385
Mass (Da):40,559
Last modified:February 22, 2012 - v1
Checksum:i0B30B0D43E0CF219
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003130 Genomic DNA. Translation: AEU38708.1.
RefSeqiYP_005059738.1. NC_016631.1.

Genome annotation databases

EnsemblBacteriaiAEU38708; AEU38708; AciX8_4435.
GeneIDi11572334.
KEGGigma:AciX8_4435.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003130 Genomic DNA. Translation: AEU38708.1 .
RefSeqi YP_005059738.1. NC_016631.1.

3D structure databases

ProteinModelPortali G8NU73.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEU38708 ; AEU38708 ; AciX8_4435 .
GeneIDi 11572334.
KEGGi gma:AciX8_4435.

Phylogenomic databases

KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci GMAL682795:GHBV-4487-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Granulicella mallensis MP5ACTX8."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Lu M., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Mikhailova N., Pagani I., Rawat S.
    , Mannisto M., Haggblom M., Woyke T.
    Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1857 / DSM 23137 / MP5ACTX8Imported.

Entry informationi

Entry nameiG8NU73_GRAMM
AccessioniPrimary (citable) accession number: G8NU73
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: November 26, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3