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Protein

DNA ligase

Gene

AciX8_2056

Organism
Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciGMAL682795:GHBV-2083-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:AciX8_2056Imported
OrganismiGranulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8)Imported
Taxonomic identifieri682795 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeGranulicella
ProteomesiUP000007113 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi682795.AciX8_2056.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10747.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8NTR2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFFVALATL AEKLSQEGSR LKKRAAIAEA IASLHAAAPE SSDAGRFALY
60 70 80 90 100
LAGQPFAEND ARKLNAGGAL LSRAVLTVAG ADNAQLTAAY RRHGDLGAAA
110 120 130 140 150
HDLLVAPHGK APSTATLTLD DVADAFAAMA VARTTAARSS LVEGLLTRAT
160 170 180 190 200
AVEAKYLLKL MLGDMRIGVK QSLIEEAIAV ASGTEVAAVR HGVMLEADLV
210 220 230 240 250
CAVGRAFAGT LAAARMTLFH PLGFMLASPV ETPEAAVERF TEAPAKEKPA
260 270 280 290 300
KVAKPKKARK KRVGEDFVDL APVQEVVARD APEEGLAEDA QIEALASGEL
310 320 330 340 350
SAGSSGVLAF LEDKYDGMRA QVHCGDPSQP GRVAIYSRNR EDITQSFPEL
360 370 380 390 400
AEAFAQVEEP MILDGEILGW DFGKSQALPF AVMGQRIGRK VVSDEVRRQI
410 420 430 440 450
PAVFMAFDLL FVGDELLLPL PLTRRRMLLE EVVARWSEHA RSALAADSTR
460 470 480 490 500
KADQAGLFSE TAPVAEQKTR WMLSPSQPVT DAAAIDQAYR DARARANEGV
510 520 530 540 550
MLKRADSAYL PGRRGLAWVK LKRELATLDV VITGAEFGHG KRAGLLSDYT
560 570 580 590 600
FAVRGQAGQL LNVGKAYSGL TDAEILEMTA WLKAHTLEDR GYFRTVEPQI
610 620 630 640 650
VLEVAFNNIM RSSRHASGFA LRFPRILHIR RDKPVSEIDT LEQVEAVYQT
660
QPDRPDESLE E
Length:661
Mass (Da):71,326
Last modified:February 22, 2012 - v1
Checksum:i7AFAE79C7406B3C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003130 Genomic DNA. Translation: AEU36386.1.
RefSeqiWP_014265264.1. NC_016631.1.
YP_005057416.1. NC_016631.1.

Genome annotation databases

EnsemblBacteriaiAEU36386; AEU36386; AciX8_2056.
KEGGigma:AciX8_2056.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003130 Genomic DNA. Translation: AEU36386.1.
RefSeqiWP_014265264.1. NC_016631.1.
YP_005057416.1. NC_016631.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi682795.AciX8_2056.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEU36386; AEU36386; AciX8_2056.
KEGGigma:AciX8_2056.

Phylogenomic databases

KOiK10747.

Enzyme and pathway databases

BioCyciGMAL682795:GHBV-2083-MONOMER.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Granulicella mallensis MP5ACTX8."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Lu M., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Mikhailova N., Pagani I., Rawat S.
    , Mannisto M., Haggblom M., Woyke T.
    Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1857 / DSM 23137 / MP5ACTX8Imported.

Entry informationi

Entry nameiG8NTR2_GRAMM
AccessioniPrimary (citable) accession number: G8NTR2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: June 24, 2015
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.