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G8NSU7 (G8NSU7_GRAMM) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length463 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate. HAMAP-Rule MF_01107

Cofactor

Binds 1 pyridoxal phosphate per subunit By similarity. HAMAP-Rule MF_01107

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 4/4. HAMAP-Rule MF_01107

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01107

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01107.

Miscellaneous

May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis By similarity. HAMAP-Rule MF_01107

Sequence similarities

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. HAMAP-Rule MF_01107

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region281 – 2844Pyridoxal phosphate binding By similarity HAMAP-Rule MF_01107

Sites

Binding site1711Pyridoxal phosphate; via carbonyl oxygen By similarity HAMAP-Rule MF_01107
Binding site1741N2-acetyl-L-ornithine By similarity HAMAP-Rule MF_01107
Binding site3371N2-acetyl-L-ornithine By similarity HAMAP-Rule MF_01107
Binding site3381Pyridoxal phosphate By similarity HAMAP-Rule MF_01107

Amino acid modifications

Modified residue3101N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01107

Sequences

Sequence LengthMass (Da)Tools
G8NSU7 [UniParc].

Last modified February 22, 2012. Version 1.
Checksum: 6B7B6A0434528647

FASTA46350,369
        10         20         30         40         50         60 
MSILLEDRLT NQFQTVCDEE MARFGPKLKT VLPGPKAKAV IEADERFMSP SYTRGYPLVA 

        70         80         90        100        110        120 
KRGRGTRMED VDGNEFLDFS AGIAVTSTGH CHPKVVKAIQ EQAAELIHMS GTDFYYEGMP 

       130        140        150        160        170        180 
ALAQRLSAVA PMKGPHKFYY GNSGAEAVEC ALKLARYHTG RQNIISFLGS FHGRTMGALS 

       190        200        210        220        230        240 
LTASKPQQKR RFAPLVPGVT HVPYPYAYRG AGTGQSEDEY ALACARYIED RLFKTMLPPE 

       250        260        270        280        290        300 
EVAAIFVEPI QGEGGYVVAP TVFLQELRNI CDRHGILLVV DEVQSGAGRT GKWWAVQHTG 

       310        320        330        340        350        360 
VEPDMVCMAK GIASGMPLSV CMTRAEIMDW KPGSHASTFG GNPVAIAAAL ATMDVLEEEA 

       370        380        390        400        410        420 
ISNAAAVGAE IKARAETWLS KYEIVGDIRG RGLMIGIEIV KDKKSKQPHS AVRDAIVDRA 

       430        440        450        460 
FEHGLLFLGC GETSIRLSPP LTISREEAAI AMDVLEQCIA EQC 

« Hide

References

[1]"Complete sequence of Granulicella mallensis MP5ACTX8."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Lu M., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Mikhailova N., Pagani I., Rawat S. expand/collapse author list , Mannisto M., Haggblom M., Woyke T.
Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1857 / DSM 23137 / MP5ACTX8.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003130 Genomic DNA. Translation: AEU36290.1.
RefSeqYP_005057320.1. NC_016631.1.

3D structure databases

ProteinModelPortalG8NSU7.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEU36290; AEU36290; AciX8_1960.
GeneID11573066.
KEGGgma:AciX8_1960.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00823.

Enzyme and pathway databases

BioCycGMAL682795:GHBV-1986-MONOMER.
UniPathwayUPA00068; UER00109.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
HAMAPMF_01107. ArgD_aminotrans_3.
InterProIPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR004636. Trfase_AcOrn/SuccOrn_fam.
[Graphical view]
PANTHERPTHR11986. PTHR11986. 1 hit.
PfamPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMSSF53383. SSF53383. 1 hit.
PROSITEPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG8NSU7_GRAMM
AccessionPrimary (citable) accession number: G8NSU7
Entry history
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: February 19, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)