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G8NK31 (G8NK31_BRUSS) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 8. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phenylalanine--tRNA ligase alpha subunit HAMAP-Rule MF_00281
EC=6.1.1.20 HAMAP-Rule MF_00281
Alternative name(s):
Phenylalanyl-tRNA synthetase alpha subunit HAMAP-Rule MF_00281
Gene names
Name:pheS HAMAP-Rule MF_00281 EMBL AEU07099.1
ORF Names:BSVBI22_A2118 EMBL AEU07099.1
OrganismBrucella suis VBI22 EMBL AEU07099.1
Taxonomic identifier1112912 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella ›

Protein attributes

Sequence length369 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe). HAMAP-Rule MF_00281 SAAS SAAS004529

Cofactor

Binds 2 magnesium ions per tetramer By similarity. HAMAP-Rule MF_00281 SAAS SAAS004529

Subunit structure

Tetramer of two alpha and two beta subunits By similarity. HAMAP-Rule MF_00281 SAAS SAAS004529

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00281 SAAS SAAS004529.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. HAMAP-Rule MF_00281

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2691Magnesium By similarity HAMAP-Rule MF_00281

Sequences

Sequence LengthMass (Da)Tools
G8NK31 [UniParc].

Last modified February 22, 2012. Version 1.
Checksum: BC2B822DB0270926

FASTA36941,598
        10         20         30         40         50         60 
MSDLEQLERQ ILEDIAAAVD EQGIEAVRVA ALGKKGTVSE KLKTLGGMSP EERQMQGPAI 

        70         80         90        100        110        120 
NGLKNRVTEA LSERRTELRK AAVAARLERE KVDVTLPVRE SAASRGRIHP ISQVIDEITA 

       130        140        150        160        170        180 
IFADMGFSIA EGPDIETDYY NFTALNFPEG HPAREMHDTF FFNPDEKGER KLLRTHTSPV 

       190        200        210        220        230        240 
QVHTMEKFAA MRDKEGRDEP IRIVIPGKTY RMDSDATHSP MFHQVEGLVV DKSANVANMK 

       250        260        270        280        290        300 
WVLEEFCKAF FEVPSVKMRM RPSFFPFTEP SVEVDIQCDR SGPHVKFGEG NDWLEILGCG 

       310        320        330        340        350        360 
MVHPNVLRMS GYDPEVYQGF AWGMGIDRIA MLKYGMPDLR AFFDADVRWI EHYGFRPLDI 


PTLFGGLSA

« Hide

References

[1]"Complete Genome Sequence of Brucella suis VBI22, Isolated from Bovine Milk."
Tae H., Shallom S., Settlage R., Hawkins G.N., Adams L.G., Garner H.R.
J. Bacteriol. 194:910-910(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: VBI22 EMBL AEU07099.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP003128 Genomic DNA. Translation: AEU07099.1.
RefSeqYP_005155771.1. NC_016797.1.

3D structure databases

ProteinModelPortalG8NK31.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEU07099; AEU07099; BSVBI22_A2118.
GeneID11727518.
KEGGbsv:BSVBI22_A2118.

Phylogenomic databases

KOK01889.

Family and domain databases

HAMAPMF_00281. Phe_tRNA_synth_alpha1.
InterProIPR006195. aa-tRNA-synth_II.
IPR004529. Phe-tRNA-synth_IIc_asu.
IPR004188. Phe-tRNA_ligase_II_N.
IPR022911. Phe_tRNA_ligase_alpha1_bac.
IPR002319. Phenylalanyl-tRNA_Synthase.
IPR010978. tRNA-bd_arm.
[Graphical view]
PfamPF02912. Phe_tRNA-synt_N. 1 hit.
PF01409. tRNA-synt_2d. 1 hit.
[Graphical view]
SUPFAMSSF46589. tRNA_binding_arm. 1 hit.
TIGRFAMsTIGR00468. pheS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG8NK31_BRUSS
AccessionPrimary (citable) accession number: G8NK31
Entry history
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: April 3, 2013
This is version 8 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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