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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Thermus sp. CCB_US3_UF1
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei145 – 1451UniRule annotation
Active sitei531 – 5311UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciTSP1111069:GLMD-1098-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:TCCBUS3UF1_10880Imported
OrganismiThermus sp. CCB_US3_UF1Imported
Taxonomic identifieri1111069 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
ProteomesiUP000005635 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8NCZ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPEPFDRLR AEVDLLGRLL GEAIRAVSGE RILALVEEVR HLAKARRQGE
60 70 80 90 100
EGAGEALGRR VEGLSLAEAE ALVRAFTHYF HLVNLAEERH RVRVNRLRAE
110 120 130 140 150
AETLENPRPE GFLALAKALK ERGLSLEEAE AHLNRLELHL TFTAHPTETR
160 170 180 190 200
RRTLRHHLER LGEELEAGEK ERLLARVALL YATEEVRKAR PSVEDEIKGG
210 220 230 240 250
LYYLPTTLWR AIPRVVAGLE AALERVYGRR PRLRSPVRFR SWIGGDRDGN
260 270 280 290 300
PFVTPEVTAF AARYARQVAR ERFLQELEAL VRDLSLAEAR VPVPREVRSG
310 320 330 340 350
GEGVERFPGE AYRRFFAGLY GRLEREELTT EGLLRAVRLA EGGLEGVGLG
360 370 380 390 400
PVARAFLRPL EARLTAFGLE LAPLDLREES AKLLEAAAEL LRAGGVHPDL
410 420 430 440 450
LSLPPEAQEA LLTEELGSAR PLLPVGEEPQ GEALRVALGS MRAWRDKGAH
460 470 480 490 500
VVSMTHHPAD LLAVFLLARE VGLYRPGRPL PLDVVPLFET LEDLHRAPEV
510 520 530 540 550
LRRLLGNPVF RTHAQGRGGV EVMIGYSDSN KDAGFLAANL ALYEAQEALA
560 570 580 590 600
QVGREAGLPV FFFHGRGTST ARGGGPAGRA IASLPPRSVG HRLRLTEQGE
610 620 630 640 650
ALADRYAHPD LAVRHLEQLL FHFAQAALGE GREPEPAWRE ALRGAAEESM
660 670 680 690 700
GRYRALLGQE GFFPFFEAFT PIREIGELPI ASRPVYRHGR VREIRDLRAI
710 720 730 740 750
PWVMAWTQVR LLLPGWYGLS ALEGLPLSLL RGMYRGWPFF ATTLESAAMA
760 770 780 790 800
LAKADLGVAR LYLRLVPEAL HPFFHHLAEE YRKTVALLEA IFEAPLLHNQ
810 820 830 840 850
RTLERQIALR NPYVDPINFV QVELLARYRA PGGREDEGVR KALLLSLLGV

AAGLRNAG
Length:858
Mass (Da):95,501
Last modified:February 22, 2012 - v1
Checksum:i2FEA79755D7BD47F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003126 Genomic DNA. Translation: AEV16133.1.
RefSeqiWP_014515492.1. NC_017278.1.
YP_005654207.1. NC_017278.1.

Genome annotation databases

EnsemblBacteriaiAEV16133; AEV16133; TCCBUS3UF1_10880.
KEGGithc:TCCBUS3UF1_10880.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003126 Genomic DNA. Translation: AEV16133.1.
RefSeqiWP_014515492.1. NC_017278.1.
YP_005654207.1. NC_017278.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEV16133; AEV16133; TCCBUS3UF1_10880.
KEGGithc:TCCBUS3UF1_10880.

Phylogenomic databases

KOiK01595.

Enzyme and pathway databases

BioCyciTSP1111069:GLMD-1098-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of thermophilic Thermus sp. CCB_US3_UF1."
    Teh B.S., Abdul Rahman A.Y., Saito J.A., Hou S., Alam M.
    Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CCB_US3_UF1Imported.

Entry informationi

Entry nameiG8NCZ2_9DEIN
AccessioniPrimary (citable) accession number: G8NCZ2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: April 29, 2015
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.