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G8N4X7 (G8N4X7_GEOTH) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 8. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phosphofructokinase HAMAP-Rule MF_00339
Short name=Phosphofructokinase HAMAP-Rule MF_00339
EC=2.7.1.11 HAMAP-Rule MF_00339
Alternative name(s):
Phosphohexokinase HAMAP-Rule MF_00339
Gene names
Name:pfkA HAMAP-Rule MF_00339
ORF Names:GTCCBUS3UF5_30850 EMBL AEV20387.1
OrganismGeobacillus thermoleovorans CCB_US3_UF5 EMBL AEV20387.1
Taxonomic identifier1111068 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Geobacillus ›

Protein attributes

Sequence length339 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate. SAAS SAAS000023 HAMAP-Rule MF_00339

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4. SAAS SAAS000023 HAMAP-Rule MF_00339

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00339 SAAS SAAS000023.

Sequence similarities

Belongs to the phosphofructokinase family. HAMAP-Rule MF_00339

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding41 – 455ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding174 – 1785ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding191 – 20717ATP By similarity HAMAP-Rule MF_00339

Sites

Active site1471Proton acceptor By similarity HAMAP-Rule MF_00339
Metal binding2051Magnesium; via carbonyl oxygen By similarity HAMAP-Rule MF_00339
Metal binding2071Magnesium By similarity HAMAP-Rule MF_00339
Binding site1821Substrate By similarity HAMAP-Rule MF_00339
Binding site2631Substrate By similarity HAMAP-Rule MF_00339
Binding site2691Substrate By similarity HAMAP-Rule MF_00339
Binding site2721Substrate By similarity HAMAP-Rule MF_00339

Sequences

Sequence LengthMass (Da)Tools
G8N4X7 [UniParc].

Last modified February 22, 2012. Version 1.
Checksum: 3A6C3DE2532BEA98

FASTA33936,525
        10         20         30         40         50         60 
MFKKTYEVGR VQFDANEVEM MKRIGVLTSG GDSPGMNAAI RAVVRKAIYH GVEVYGIYHG 

        70         80         90        100        110        120 
YAGLIAGNIK KLEVGDVGDI IHRGGTILYT ARCPEFKTEE GQKKGIEQLK KHGIEGLVVI 

       130        140        150        160        170        180 
GGDGSYQGAK KLTEHGFPCV GVPGTIDNDI PGTDFTIGFD TALNTVIDAI DKIRDTATSH 

       190        200        210        220        230        240 
ERTYVVEVMG RHAGDIALWS GLAGGAETIL IPEADYDMDD IIARLKRGHE RGKKHSIIIV 

       250        260        270        280        290        300 
AEGVGSGVDF GRQIQEATGF ETRVTVLGHV QRGGSPTAFD RVLASRLGAR AVELLLEGKG 

       310        320        330 
GRCVGIQNNQ IVDHDIAEAL AKTHTVDQRM YTLSKELSI

« Hide

References

[1]"Complete genome sequence of thermophilic Geobacillus thermoleovorans CCB_US3_UF5."
Muhd Sakaff M.K.L., Abdul Rahman A.Y., Saito J.A., Hou S., Alam M.
Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: CCB_US3_UF5 EMBL AEV20387.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP003125 Genomic DNA. Translation: AEV20387.1.
RefSeqYP_004983487.1. NC_016593.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEV20387; AEV20387; GTCCBUS3UF5_30850.
GeneID11627314.
KEGGgte:GTCCBUS3UF5_30850.

Phylogenomic databases

KOK00850.

Enzyme and pathway databases

UniPathwayUPA00109; UER00182.

Family and domain databases

HAMAPMF_00339. Phosphofructokinase.
InterProIPR012003. ATP_PFK_prok.
IPR012828. PFKA_ATP.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamPF00365. PFK. 1 hit.
[Graphical view]
PIRSFPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSPR00476. PHFRCTKINASE.
SUPFAMSSF53784. Ppfruckinase. 1 hit.
TIGRFAMsTIGR02482. PFKA_ATP. 1 hit.
PROSITEPS00433. PHOSPHOFRUCTOKINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG8N4X7_GEOTH
AccessionPrimary (citable) accession number: G8N4X7
Entry history
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: April 3, 2013
This is version 8 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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