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G8MDQ6

- G8MDQ6_9BURK

UniProt

G8MDQ6 - G8MDQ6_9BURK

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Protein

Ribulose bisphosphate carboxylase large chain

Gene

cbbL

Organism
Burkholderia sp. YI23
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.UniRule annotation

Catalytic activityi

2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O.UniRule annotation
3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2.UniRule annotation

Cofactori

Binds 1 magnesium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei136 – 1361Substrate; in homodimeric partnerUniRule annotation
Binding sitei186 – 1861SubstrateUniRule annotation
Active sitei188 – 1881Proton acceptorUniRule annotation
Binding sitei190 – 1901SubstrateUniRule annotation
Metal bindingi214 – 2141Magnesium; via carbamate groupUniRule annotation
Metal bindingi216 – 2161MagnesiumUniRule annotation
Metal bindingi217 – 2171MagnesiumUniRule annotation
Active sitei306 – 3061Proton acceptorUniRule annotation
Binding sitei307 – 3071SubstrateUniRule annotation
Binding sitei339 – 3391SubstrateUniRule annotation
Sitei346 – 3461Transition state stabilizerUniRule annotation
Binding sitei391 – 3911SubstrateUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. monooxygenase activity Source: UniProtKB-KW
  3. ribulose-bisphosphate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. reductive pentose-phosphate cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation, MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Biological processi

Calvin cycleUniRule annotation, Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciBSP1097668:GKEO-5926-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribulose bisphosphate carboxylase large chainUniRule annotation (EC:4.1.1.39UniRule annotation)
Short name:
RuBisCO large subunitUniRule annotation
Gene namesi
Name:cbbLUniRule annotation
ORF Names:BYI23_B014300Imported
OrganismiBurkholderia sp. YI23Imported
Taxonomic identifieri1097668 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000006801: Chromosome 2

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei214 – 2141N6-carboxylysineUniRule annotation

Interactioni

Subunit structurei

Heterohexadecamer of 8 large chains and 8 small chains.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the RuBisCO large chain family. Type I subfamily.UniRule annotation

Phylogenomic databases

KOiK01601.

Family and domain databases

Gene3Di3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
HAMAPiMF_01338. RuBisCO_L_type1.
InterProiIPR020878. RuBisCo_large_chain_AS.
IPR020888. RuBisCO_lsu.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view]
PfamiPF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view]
SUPFAMiSSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
PROSITEiPS00157. RUBISCO_LARGE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8MDQ6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNDFSKAAVE AARNPSDPRS RYAAGVMKYR EMGYWQPDYT PKDTDVIALF
60 70 80 90 100
RITPQAGVEP EEAAAAVAGE SSTATWTVVW TDRLTACDMY RAKAYRVDPV
110 120 130 140 150
PNQRADEPQY FAYIAYELDL FEEGSVANLT ASIIGNVFGF KPLKALRLED
160 170 180 190 200
MRIPVAYLKT FQGPPTGIIV ERERLDKYGR PLLGATVKPK LGLSGKNYGR
210 220 230 240 250
VVYEGLKGGL DFLKDDENIN SQAFMHWRDR YLFAMEAVSR AQAETGEVKG
260 270 280 290 300
HYLNVTAGTM EDMYERAEFA KELGSCIVMI DLVIGWTAIQ SMSKWARRND
310 320 330 340 350
MILHLHRAGH GTYTRQRNHG ISFRVIAKWL RMAGVDHAHA GTAVGKLEGD
360 370 380 390 400
PLSVQGYYNV CREARNEPDL SRGIFFDQPW AGLRKVMPVA SGGIHAGQMH
410 420 430 440 450
QLLDLFGDDC ILQFGGGTIG HPQGIQAGAT ANRVALEAMV KARNEGRDIV
460 470 480 490
NEGLDVLDAA ARFCTPLKLA LDTWRDVTFN YASTDTPDFA VTPSVAV
Length:497
Mass (Da):55,048
Last modified:February 22, 2012 - v1
Checksum:i370A0F2ADDB00C72
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003088 Genomic DNA. Translation: AET92037.1.
RefSeqiWP_014251670.1. NC_016625.1.
YP_005042924.1. NC_016625.1.

Genome annotation databases

EnsemblBacteriaiAET92037; AET92037; BYI23_B014300.
GeneIDi11558245.
KEGGibyi:BYI23_B014300.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003088 Genomic DNA. Translation: AET92037.1 .
RefSeqi WP_014251670.1. NC_016625.1.
YP_005042924.1. NC_016625.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AET92037 ; AET92037 ; BYI23_B014300 .
GeneIDi 11558245.
KEGGi byi:BYI23_B014300.

Phylogenomic databases

KOi K01601.

Enzyme and pathway databases

BioCyci BSP1097668:GKEO-5926-MONOMER.

Family and domain databases

Gene3Di 3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
HAMAPi MF_01338. RuBisCO_L_type1.
InterProi IPR020878. RuBisCo_large_chain_AS.
IPR020888. RuBisCO_lsu.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view ]
Pfami PF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view ]
SUPFAMi SSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
PROSITEi PS00157. RUBISCO_LARGE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of the Fenitrothion-Degrading Burkholderia sp. Strain YI23."
    Lim J.S., Choi B.S., Choi A.Y., Kim K.D., Kim D.I., Choi I.Y., Ka J.O.
    J. Bacteriol. 194:896-896(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: YI23Imported.

Entry informationi

Entry nameiG8MDQ6_9BURK
AccessioniPrimary (citable) accession number: G8MDQ6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: October 29, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

The basic functional RuBisCO is composed of a large chain homodimer in a "head-to-tail" conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric "cap" on each end of the "barrel".UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3