G8MCK1 (G8MCK1_9BURK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2-dehydropantoate 2-reductase RuleBase RU003776
EC=1.1.1.169 RuleBase RU003776

Gene names

ORF Names:

BYI23_B012110 EMBL AET91818.1

Organism

Burkholderia sp. YI23 EMBL AET91818.1

Taxonomic identifier

1097668 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length	308 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid By similarity. RuleBase RU003776
Catalytic activity	(R)-pantoate + NADP+ = 2-dehydropantoate + NADPH. RuleBase RU003776
Pathway	Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 2/2. RuleBase RU004251
Sequence similarities	Belongs to the ketopantoate reductase family. RuleBase RU003776

Ontologies

Keywords
Biological process	Pantothenate biosynthesis RuleBase RU003776
Ligand	NADP RuleBase RU003776
Molecular function	Oxidoreductase RuleBase RU003776
Gene Ontology (GO)
Biological_process	pantothenate biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	2-dehydropantoate 2-reductase activity Inferred from electronic annotation. Source: EC NADP binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	G8MCK1 [UniParc]. Last modified February 22, 2012. Version 1. Checksum: 9DDC3253E25D1119	FASTA	308	33,135
	10 20 30 40 50 60 MRILVVGAGA IGGYFGARLL DAGRDVTFLV RERRAERLRQ CGLKVKTPDG DLEFACPPMV 70 80 90 100 110 120 LAKDIERPYD LVLLSCKAYD LQGAIDSFAP AVGEDTLILP LLNGMAHLDA LDARFNPANV 130 140 150 160 170 180 LGGQCSIAAT LNPEGEIVQM SSLHSLVFGE RAGGRTPRID AVAGQLDGAG FDLTVSENVL 190 200 210 220 230 240 QSMWDKWVFL ATLATGTCLM RAPIGDILSA PGGEDVLRRL FIECQGIAAD NDHPPAEAAL 250 260 270 280 290 300 ERARAFFTDR SSTMTASMLR DLENGAAIEA DHIVGDLIAR RRTKPEGASM LEVAYAHLKA YEARRARA

References

[1]	"Complete Genome Sequence of the Fenitrothion-Degrading Burkholderia sp. Strain YI23." Lim J.S., Choi B.S., Choi A.Y., Kim K.D., Kim D.I., Choi I.Y., Ka J.O. J. Bacteriol. 194:896-896(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: YI23 EMBL AET91818.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP003088 Genomic DNA. Translation: AET91818.1.
RefSeq	YP_005042705.1. NC_016625.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AET91818; AET91818; BYI23_B012110.
GeneID	11558026.
KEGG	byi:BYI23_B012110.
Phylogenomic databases
KO	K00077.
Enzyme and pathway databases
BioCyc	BSP1097668:GKEO-5707-MONOMER.
UniPathway	UPA00028; UER00004.
Family and domain databases
Gene3D	1.10.1040.10. 1 hit. 3.40.50.720. 1 hit.
InterPro	IPR008927. 6-PGluconate_DH_C-like. IPR003710. ApbA. IPR013752. ApbA_C. IPR013332. ApbA_N. IPR013328. DH_multihelical. IPR016040. NAD(P)-bd_dom. [Graphical view]
Pfam	PF02558. ApbA. 1 hit. PF08546. ApbA_C. 1 hit. [Graphical view]
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMs	TIGR00745. apbA_panE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

G8MCK1_9BURK

Accession

Primary (citable) accession number: G8MCK1

Entry history

Integrated into UniProtKB/TrEMBL:	February 22, 2012
Last sequence update:	February 22, 2012
Last modified:	May 29, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)