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G8M2J8 (G8M2J8_CLOCD) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Histidinol-phosphate aminotransferase HAMAP-Rule MF_01023
EC=2.6.1.9 HAMAP-Rule MF_01023
Alternative name(s):
Imidazole acetol-phosphate transaminase HAMAP-Rule MF_01023
Gene names
Name:hisC HAMAP-Rule MF_01023
Ordered Locus Names:Clocl_3928 EMBL AEV70368.1
OrganismClostridium clariflavum (strain DSM 19732 / NBRC 101661 / EBR45) [Complete proteome] [HAMAP] EMBL AEV70368.1
Taxonomic identifier720554 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium ›

Protein attributes

Sequence length357 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. SAAS SAAS005861 HAMAP-Rule MF_01023

Cofactor

Pyridoxal phosphate By similarity. SAAS SAAS005861 HAMAP-Rule MF_01023

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. SAAS SAAS005861 HAMAP-Rule MF_01023

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01023

Sequence similarities

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP-Rule MF_01023

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2171N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01023

Sequences

Sequence LengthMass (Da)Tools
G8M2J8 [UniParc].

Last modified February 22, 2012. Version 1.
Checksum: 4C7D65E316681903

FASTA35739,780
        10         20         30         40         50         60 
MIRDLIRSEL KDFVPYTANQ VPYRVKLDAN ESPFDLPMSV RKKLADIIME GPKLNLYPDT 

        70         80         90        100        110        120 
DSIELRKTLS AYWGVDMEGI VVGTGSDELI QVLINTFVGK GDKVVCPVPS FGMYKITTII 

       130        140        150        160        170        180 
GGGSTVEVAL KEENGFEYDI DEFISKAKNE KAKMVILCSP NNPTGNLLSL RDIEKICSMC 

       190        200        210        220        230        240 
PNTVIVVDEA YAEFSEESAV ELLPKFENLI ILRTFSKAYG LAGIRCGYSL SGKAMADEIN 

       250        260        270        280        290        300 
KVKPPFNISS LSQLVAKLVF EEREEIDRRI KYLTEQRTYL AEELKKIKGV TIFPSGANYI 

       310        320        330        340        350 
LVKLPDAQAV AKELERRGIL VRGYGDPVLS KYIRITVGSK EQNDILLEEL ANILASN

« Hide

References

[1]"Complete sequence of Clostridium clariflavum DSM 19732."
US DOE Joint Genome Institute
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Kitzmiller T., Lynd L., Izquierdo J., Woyke T.
Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 19732 / NBRC 101661 / EBR45.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP003065 Genomic DNA. Translation: AEV70368.1.
RefSeqYP_005048292.1. NC_016627.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEV70368; AEV70368; Clocl_3928.
GeneID11560672.
KEGGccl:Clocl_3928.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00817.

Enzyme and pathway databases

BioCycCCLA720554:GI2T-3919-MONOMER.
UniPathwayUPA00031; UER00012.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
HAMAPMF_01023. HisC_aminotrans_2.
InterProIPR001917. Aminotrans_II_pyridoxalP_BS.
IPR004839. Aminotransferase_I/II.
IPR005861. HisP_aminotrans.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR01141. hisC. 1 hit.
PROSITEPS00599. AA_TRANSFER_CLASS_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG8M2J8_CLOCD
AccessionPrimary (citable) accession number: G8M2J8
Entry history
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: May 29, 2013
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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