Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Xylose isomerase

Gene

xylA

Organism
Enterobacter cloacae EcWSU1
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei122 – 1221UniRule annotation
Active sitei125 – 1251UniRule annotation
Metal bindingi253 – 2531Magnesium 1UniRule annotation
Metal bindingi289 – 2891Magnesium 1UniRule annotation
Metal bindingi289 – 2891Magnesium 2UniRule annotation
Metal bindingi292 – 2921Magnesium 2UniRule annotation
Metal bindingi317 – 3171Magnesium 1UniRule annotation
Metal bindingi328 – 3281Magnesium 2UniRule annotation
Metal bindingi330 – 3301Magnesium 2UniRule annotation
Metal bindingi360 – 3601Magnesium 1UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciECLO1045856:GHCE-172-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotationImported
ORF Names:EcWSU1_00171Imported
OrganismiEnterobacter cloacae EcWSU1Imported
Taxonomic identifieri1045856 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEnterobacterEnterobacter cloacae complex
ProteomesiUP000007838 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi1045856.EcWSU1_00171.

Structurei

3D structure databases

ProteinModelPortaliG8LGL7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8LGL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIHYYSCIN DSPHTLIMEL NMQAYFDQLD RVRYEGPKTT NPLAFRHYNP
60 70 80 90 100
DELVLGKRME DHLRFAACYW HTFCWNGADM FGVGSFDRPW QQPGEAIELA
110 120 130 140 150
KRKADVAFEF FHKLNVPYYC FHDVDVSPEG ASLKEYLNNF AQMVDVLAAK
160 170 180 190 200
QQQSGVKLLW GTANCFTNPR YGAGAATNPD PEVFSWAATQ VVTAMNATHQ
210 220 230 240 250
LGGENYVLWG GREGYETLLN TDLRQEREQI GRFMQMVVDH KHKIGFRGTL
260 270 280 290 300
LIEPKPQEPT KHQYDYDVAT VYGFLKQFGL EKEIKVNIEA NHATLAGHSF
310 320 330 340 350
HHEIASAIAL GIFGSVDANR GDAQLGWDTD QFPNSVEENA LVMYEIIKAG
360 370 380 390 400
GFTTGGLNFD AKVRRQSTDK YDLFYGHIGA MDTMALALKV AARMIEDGEL
410 420 430 440 450
DKRVAKRYSG WNSELGQQIL KGQLSLADVA KYAEQHQLAP QHQSGHQELL
460
ENLVNHYLFD K
Length:461
Mass (Da):52,219
Last modified:February 22, 2012 - v1
Checksum:i4D28A20700444843
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002886 Genomic DNA. Translation: AEW71611.1.

Genome annotation databases

EnsemblBacteriaiAEW71611; AEW71611; EcWSU1_00171.
KEGGieec:EcWSU1_00171.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002886 Genomic DNA. Translation: AEW71611.1.

3D structure databases

ProteinModelPortaliG8LGL7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi1045856.EcWSU1_00171.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEW71611; AEW71611; EcWSU1_00171.
KEGGieec:EcWSU1_00171.

Phylogenomic databases

KOiK01805.

Enzyme and pathway databases

BioCyciECLO1045856:GHCE-172-MONOMER.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: EcWSU1Imported.

Entry informationi

Entry nameiG8LGL7_ENTCL
AccessioniPrimary (citable) accession number: G8LGL7
Entry historyi
Integrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: July 22, 2015
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.