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G8LGL7

- G8LGL7_ENTCL

UniProt

G8LGL7 - G8LGL7_ENTCL

Protein

Xylose isomerase

Gene

xylA

Organism
Enterobacter cloacae EcWSU1
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (22 Feb 2012)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

    Cofactori

    Binds 2 magnesium ions per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei122 – 1221UniRule annotation
    Active sitei125 – 1251UniRule annotation
    Metal bindingi253 – 2531Magnesium 1UniRule annotation
    Metal bindingi289 – 2891Magnesium 1UniRule annotation
    Metal bindingi289 – 2891Magnesium 2UniRule annotation
    Metal bindingi292 – 2921Magnesium 2UniRule annotation
    Metal bindingi317 – 3171Magnesium 1UniRule annotation
    Metal bindingi328 – 3281Magnesium 2UniRule annotation
    Metal bindingi330 – 3301Magnesium 2UniRule annotation
    Metal bindingi360 – 3601Magnesium 1UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. xylose isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-xylose metabolic process Source: UniProtKB-HAMAP
    2. pentose-phosphate shunt Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotation, Xylose metabolismUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciECLO1045856:GHCE-172-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
    Gene namesi
    Name:xylAUniRule annotationImported
    ORF Names:EcWSU1_00171Imported
    OrganismiEnterobacter cloacae EcWSU1Imported
    Taxonomic identifieri1045856 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEnterobacterEnterobacter cloacae complex
    ProteomesiUP000007838: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotationSAAS annotation

    Structurei

    3D structure databases

    ProteinModelPortaliG8LGL7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the xylose isomerase family.UniRule annotation

    Phylogenomic databases

    KOiK01805.

    Family and domain databases

    Gene3Di3.20.20.150. 1 hit.
    HAMAPiMF_00455. Xylose_isom_A.
    InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013452. Xylose_isom_bac.
    IPR001998. Xylose_isomerase.
    [Graphical view]
    PfamiPF01261. AP_endonuc_2. 1 hit.
    [Graphical view]
    PRINTSiPR00688. XYLOSISMRASE.
    SUPFAMiSSF51658. SSF51658. 1 hit.
    TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
    PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G8LGL7-1 [UniParc]FASTAAdd to Basket

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    MSIHYYSCIN DSPHTLIMEL NMQAYFDQLD RVRYEGPKTT NPLAFRHYNP    50
    DELVLGKRME DHLRFAACYW HTFCWNGADM FGVGSFDRPW QQPGEAIELA 100
    KRKADVAFEF FHKLNVPYYC FHDVDVSPEG ASLKEYLNNF AQMVDVLAAK 150
    QQQSGVKLLW GTANCFTNPR YGAGAATNPD PEVFSWAATQ VVTAMNATHQ 200
    LGGENYVLWG GREGYETLLN TDLRQEREQI GRFMQMVVDH KHKIGFRGTL 250
    LIEPKPQEPT KHQYDYDVAT VYGFLKQFGL EKEIKVNIEA NHATLAGHSF 300
    HHEIASAIAL GIFGSVDANR GDAQLGWDTD QFPNSVEENA LVMYEIIKAG 350
    GFTTGGLNFD AKVRRQSTDK YDLFYGHIGA MDTMALALKV AARMIEDGEL 400
    DKRVAKRYSG WNSELGQQIL KGQLSLADVA KYAEQHQLAP QHQSGHQELL 450
    ENLVNHYLFD K 461
    Length:461
    Mass (Da):52,219
    Last modified:February 22, 2012 - v1
    Checksum:i4D28A20700444843
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002886 Genomic DNA. Translation: AEW71611.1.
    RefSeqiWP_014168119.1. NC_016514.1.
    YP_004950032.1. NC_016514.1.

    Genome annotation databases

    EnsemblBacteriaiAEW71611; AEW71611; EcWSU1_00171.
    GeneIDi11486145.
    KEGGieec:EcWSU1_00171.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002886 Genomic DNA. Translation: AEW71611.1 .
    RefSeqi WP_014168119.1. NC_016514.1.
    YP_004950032.1. NC_016514.1.

    3D structure databases

    ProteinModelPortali G8LGL7.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEW71611 ; AEW71611 ; EcWSU1_00171 .
    GeneIDi 11486145.
    KEGGi eec:EcWSU1_00171.

    Phylogenomic databases

    KOi K01805.

    Enzyme and pathway databases

    BioCyci ECLO1045856:GHCE-172-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.150. 1 hit.
    HAMAPi MF_00455. Xylose_isom_A.
    InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013452. Xylose_isom_bac.
    IPR001998. Xylose_isomerase.
    [Graphical view ]
    Pfami PF01261. AP_endonuc_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00688. XYLOSISMRASE.
    SUPFAMi SSF51658. SSF51658. 1 hit.
    TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
    PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: EcWSU1Imported.

    Entry informationi

    Entry nameiG8LGL7_ENTCL
    AccessioniPrimary (citable) accession number: G8LGL7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 22, 2012
    Last sequence update: February 22, 2012
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3