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Protein

Histone deacetylase

Gene

Ecym_8290

Organism
Eremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582) (Yeast)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

Hydrolysis of an N6-acetyl-lysine residue of a histone to yield a deacetylated histone.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChromatin regulatorSAAS annotation, HydrolaseSAAS annotation
Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseSAAS annotation (EC:3.5.1.98SAAS annotation)
Gene namesi
Ordered Locus Names:Ecym_8290Imported
OrganismiEremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582) (Yeast)Imported
Taxonomic identifieri931890 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium
Proteomesi
  • UP000006790 Componenti: Chromosome 8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi931890.XP_003648386.1

Structurei

3D structure databases

ProteinModelPortaliG8JXJ5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini67 – 432Hist_deacetylInterPro annotationAdd BLAST366

Phylogenomic databases

eggNOGiKOG1343 Eukaryota
COG0123 LUCA
InParanoidiG8JXJ5
KOiK11484
OrthoDBiEOG092C345D

Family and domain databases

Gene3Di3.40.800.20, 1 hit
InterProiView protein in InterPro
IPR000286 His_deacetylse
IPR023801 His_deacetylse_dom
IPR037138 His_deacetylse_dom_sf
IPR023696 Ureohydrolase_dom_sf
PANTHERiPTHR10625 PTHR10625, 1 hit
PfamiView protein in Pfam
PF00850 Hist_deacetyl, 1 hit
PRINTSiPR01270 HDASUPER
SUPFAMiSSF52768 SSF52768, 1 hit

Sequencei

Sequence statusi: Complete.

G8JXJ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPQLDPLHKF KKQFEQFIEN NPNVKSAARS ASQIPESAKA VIILSPLSLQ
60 70 80 90 100
HRFSRNWVSK SYKKTIVERP ERLLASCMGI AAAITMYPAL FTLKSSDNRQ
110 120 130 140 150
SSLLSSHVLK VHGSDWPKEL LRLCRGAKEK IGRKQVEVPD EWNVGDIYLC
160 170 180 190 200
EETVYALRGS IGAVEYGVDS IFKGEVNKDT ANRAFVAIRP PGHHSHAATP
210 220 230 240 250
SGFCLLNNAH IAVEYAADTY GVTHAVILDF DLHHGDGTQD ICWKRAGFKA
260 270 280 290 300
DDIQDAKGEY NEFDKKFAEF PKVGYFSMHD INSFPTELNY ASKDKVKDAS
310 320 330 340 350
TCIMDAHDVN IWNIHLLPYE TEEEFNKLYQ TRYRTLFAKA DEFFKAAKLS
360 370 380 390 400
MAKDGKPFKG LVVMSAGFDA SEYEQVSMQR HGVNVPTSFY STFTKDALKL
410 420 430 440 450
AQMHTNGKII SLLEGGYSDA AIASGVFSHL IGLQNQNWIT EWGSAQVVKE
460 470 480 490 500
IVRGCKPRWK PYKTRKAGDV IRIWAEEVIR LGRSMITEFE ELLFSDGLVS
510 520 530 540 550
DFNVPRVTRS RHSEVVAKLE LQDASSLPRS DTPTPKERKS ASAGSNNTNG
560 570 580 590 600
STTTKQVPFV EQDLINGTDD EDDENYVYDE ELNKTFNRTV EDIAIDDISR
610 620 630 640 650
HLETLELVQE FAERPKEPIR ARPATQPQHN HDHQQQHHHH HQQAANYQRT
660 670 680 690 700
NATAPGGYRV PSNDTTRHLR NSRTSKFLNI EDSDISMISN VSPSKKHFIR

GGSSGRYKS
Length:709
Mass (Da):79,940
Last modified:January 25, 2012 - v1
Checksum:i431D0A51C1825CCD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002504 Genomic DNA Translation: AET41569.1
RefSeqiXP_003648386.1, XM_003648338.1

Genome annotation databases

EnsemblFungiiAET41569; AET41569; Ecym_8290
GeneIDi11469960
KEGGierc:Ecym_8290

Similar proteinsi

Entry informationi

Entry nameiG8JXJ5_ERECY
AccessioniPrimary (citable) accession number: G8JXJ5
Entry historyiIntegrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: March 28, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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