Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Fragile X mental retardation protein 1

Gene

FMR1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Fragile X mental retardation protein 1Imported
Gene namesi
Name:FMR1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

HGNCiHGNC:3775. FMR1.

PTM / Processingi

Proteomic databases

PaxDbiG8JLE9.
PeptideAtlasiG8JLE9.
PRIDEiG8JLE9.

PTM databases

iPTMnetiG8JLE9.

Expressioni

Gene expression databases

BgeeiENSG00000102081.
ExpressionAtlasiG8JLE9. baseline and differential.
GenevisibleiG8JLE9. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000359506.

Structurei

3D structure databases

ProteinModelPortaliG8JLE9.
SMRiG8JLE9. Positions 1-200, 216-334, 369-425.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 5047Agenet-likeInterPro annotationAdd
BLAST
Domaini63 – 11553Agenet-likeInterPro annotationAdd
BLAST
Domaini218 – 27962KHInterPro annotationAdd
BLAST
Domaini286 – 33247KHInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 2 KH domains.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IF9J. Eukaryota.
ENOG410ZDJG. LUCA.

Family and domain databases

Gene3Di3.30.1370.10. 3 hits.
InterProiIPR008395. Agenet-like_dom.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
[Graphical view]
PfamiPF05641. Agenet. 1 hit.
PF00013. KH_1. 2 hits.
[Graphical view]
SMARTiSM00322. KH. 2 hits.
[Graphical view]
SUPFAMiSSF54791. SSF54791. 2 hits.
PROSITEiPS51641. AGENET_LIKE. 2 hits.
PS50084. KH_TYPE_1. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G8JLE9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEELVVEVRG SNGAFYKAFV KDVHEDSITV AFENNWQPDR QIPFHDVRFP
60 70 80 90 100
PPVGYNKDIN ESDEVEVYSR ANEKEPCCWW LAKVRMIKGE FYVIEYAACD
110 120 130 140 150
ATYNEIVTIE RLRSVNPNKP ATKDTFHKIK LDVPEDLRQM CAKEAAHKDF
160 170 180 190 200
KKAVGAFSVT YDPENYQLVI LSINEVTSKR AHMLIDMHFR SLRTKLSLIM
210 220 230 240 250
RNEEASKQLE SSRQLASRFH EQFIVREDLM GLAIGTHGAN IQQARKVPGV
260 270 280 290 300
TAIDLDEDTC TFHIYGEDQD AVKKARSFLE FAEDVIQVPR NLVGKVIGKN
310 320 330 340 350
GKLIQEIVDK SGVVRVRIEA ENEKNVPQEE EIMPPNSLPS NNSRVGPNAP
360 370 380 390 400
EEKKHLDIKE NSTHFSQPNS TKVQRVLVAS SVVAGESQKP ELKAWQGMVP
410 420 430 440 450
FVFVGTKDSI ANATVLLDYH LNYLKLQQRK RGRASCAEET DGGVEGEEED
460 470 480 490 500
KEEEDVEEAS KETTITPEQI IVHVIQERLK EEQQMDPFRS ELTAIMKGVS
510 520 530
TLKHYRIPPV KVVGCARVKI VTRRKRSQTA WMVSNHS
Length:537
Mass (Da):61,043
Last modified:January 25, 2012 - v1
Checksum:i5E1324A8B0C34C26
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KC877972 Genomic DNA. No translation available.
KC877974 Genomic DNA. No translation available.
KF454876 Genomic DNA. No translation available.
KF495784 Genomic DNA. No translation available.
KF510171 Genomic DNA. No translation available.
L29074 Genomic DNA. No translation available.
RefSeqiNP_001172004.1. NM_001185075.1.
UniGeneiHs.103183.

Genome annotation databases

EnsembliENST00000370471; ENSP00000359502; ENSG00000102081.
GeneIDi2332.
UCSCiuc022cgc.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KC877972 Genomic DNA. No translation available.
KC877974 Genomic DNA. No translation available.
KF454876 Genomic DNA. No translation available.
KF495784 Genomic DNA. No translation available.
KF510171 Genomic DNA. No translation available.
L29074 Genomic DNA. No translation available.
RefSeqiNP_001172004.1. NM_001185075.1.
UniGeneiHs.103183.

3D structure databases

ProteinModelPortaliG8JLE9.
SMRiG8JLE9. Positions 1-200, 216-334, 369-425.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000359506.

PTM databases

iPTMnetiG8JLE9.

Proteomic databases

PaxDbiG8JLE9.
PeptideAtlasiG8JLE9.
PRIDEiG8JLE9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000370471; ENSP00000359502; ENSG00000102081.
GeneIDi2332.
UCSCiuc022cgc.2. human.

Organism-specific databases

CTDi2332.
HGNCiHGNC:3775. FMR1.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IF9J. Eukaryota.
ENOG410ZDJG. LUCA.

Miscellaneous databases

ChiTaRSiFMR1. human.
GenomeRNAii2332.

Gene expression databases

BgeeiENSG00000102081.
ExpressionAtlasiG8JLE9. baseline and differential.
GenevisibleiG8JLE9. HS.

Family and domain databases

Gene3Di3.30.1370.10. 3 hits.
InterProiIPR008395. Agenet-like_dom.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
[Graphical view]
PfamiPF05641. Agenet. 1 hit.
PF00013. KH_1. 2 hits.
[Graphical view]
SMARTiSM00322. KH. 2 hits.
[Graphical view]
SUPFAMiSSF54791. SSF54791. 2 hits.
PROSITEiPS51641. AGENET_LIKE. 2 hits.
PS50084. KH_TYPE_1. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiG8JLE9_HUMAN
AccessioniPrimary (citable) accession number: G8JLE9
Entry historyi
Integrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: September 7, 2016
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.