Skip Header

Contribute Send feedback
Read comments (?) or add your own

G7ZP92 (G7ZP92_STAAU) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 8. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
6-phosphofructokinase HAMAP-Rule MF_00339
Short name=Phosphofructokinase HAMAP-Rule MF_00339
EC=2.7.1.11 HAMAP-Rule MF_00339
Alternative name(s):
Phosphohexokinase HAMAP-Rule MF_00339
Gene names
Name:pfkA HAMAP-Rule MF_00339
ORF Names:SAMSHR1132_15490 EMBL CCE59390.1
OrganismStaphylococcus aureus subsp. aureus MSHR1132 EMBL CCE59390.1
Taxonomic identifier985002 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Staphylococcus ›

Protein attributes

Sequence length322 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate. SAAS SAAS000023 HAMAP-Rule MF_00339

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4. SAAS SAAS000023 HAMAP-Rule MF_00339

Subcellular location

Cytoplasm By similarity SAAS SAAS000023 HAMAP-Rule MF_00339.

Sequence similarities

Belongs to the phosphofructokinase family. HAMAP-Rule MF_00339

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding21 – 255ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding156 – 1605ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding173 – 18917ATP By similarity HAMAP-Rule MF_00339

Sites

Active site1291Proton acceptor By similarity HAMAP-Rule MF_00339
Metal binding1871Magnesium; via carbonyl oxygen By similarity HAMAP-Rule MF_00339
Metal binding1891Magnesium By similarity HAMAP-Rule MF_00339
Binding site1641Substrate By similarity HAMAP-Rule MF_00339
Binding site2451Substrate By similarity HAMAP-Rule MF_00339
Binding site2511Substrate By similarity HAMAP-Rule MF_00339
Binding site2541Substrate By similarity HAMAP-Rule MF_00339

Sequences

Sequence LengthMass (Da)Tools
G7ZP92 [UniParc].

Last modified January 25, 2012. Version 1.
Checksum: AA11B2DA8D59793A

FASTA32234,840
        10         20         30         40         50         60 
MKKIAVLTSG GDSPGMNAAV RAVVRTAIYN EIEVYGVYHG YQGLLNDDIH KLELGSVGDT 

        70         80         90        100        110        120 
IQRGGTFLYS ARCPEFKEQE VRKVAIENLR KRGIEGLVVI GGDGSYRGAQ RISEECKEIQ 

       130        140        150        160        170        180 
TIGIPGTIDN DINGTDFTIG FDTALNTIIG LVDKIRDTAS SHARTFIIEA MGRDCGDLAL 

       190        200        210        220        230        240 
WAGLSVGAET IVVPEVKTDI KEIADKIEQG IKRGKKHSIV LVAEGCMTAQ ECQKELSEYI 

       250        260        270        280        290        300 
NVDNRVSVLG HVQRGGSPTG ADRVLASRLG GFAVDLLMEG ETAKGVGIKN NKIVATSFDE 

       310        320 
IFDGKDHKFD YSLYELANKL SI

« Hide

References

[1]"A very early-branching Staphylococcus aureus lineage lacking the carotenoid pigment staphyloxanthin."
Holt D.C., Holden M.T., Tong S.Y., Castillo-Ramirez S., Clarke L., Quail M.A., Currie B.J., Parkhill J., Bentley S.D., Feil E.J., Giffard P.M.
Genome Biol. Evol. 3:881-895(2011)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: MSHR1132 EMBL CCE59390.1.
[2]Holden M.
Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: MSHR1132 EMBL CCE59390.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FR821777 Genomic DNA. Translation: CCE59390.1.
RefSeqYP_005326059.1. NC_016941.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCCE59390; CCE59390; SAMSHR1132_15490.
GeneID11931668.
KEGGsuh:SAMSHR1132_15490.

Phylogenomic databases

KOK00850.

Enzyme and pathway databases

UniPathwayUPA00109; UER00182.

Family and domain databases

HAMAPMF_00339. Phosphofructokinase.
InterProIPR012003. ATP_PFK_prok.
IPR012828. PFKA_ATP.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamPF00365. PFK. 1 hit.
[Graphical view]
PIRSFPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSPR00476. PHFRCTKINASE.
SUPFAMSSF53784. Ppfruckinase. 1 hit.
TIGRFAMsTIGR02482. PFKA_ATP. 1 hit.
PROSITEPS00433. PHOSPHOFRUCTOKINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG7ZP92_STAAU
AccessionPrimary (citable) accession number: G7ZP92
Entry history
Integrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: April 3, 2013
This is version 8 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info