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Protein

Alanine racemase

Gene

AZOLI_p50284

Organism
Azospirillum lipoferum (strain 4B)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Pathwayi: D-alanine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes D-alanine from L-alanine.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Alanine racemase (AZOLI_p50284)
This subpathway is part of the pathway D-alanine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-alanine from L-alanine, the pathway D-alanine biosynthesis and in Amino-acid biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei41Proton acceptor; specific for D-alanineUniRule annotation1
Binding sitei147SubstrateUniRule annotation1
Active sitei269Proton acceptor; specific for L-alanineUniRule annotation1
Binding sitei317Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
LigandPyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciALIP862719:GJAA-5841-MONOMER
UniPathwayiUPA00042; UER00497

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:AZOLI_p50284Imported
Encoded oniPlasmid AZO_p5Imported
OrganismiAzospirillum lipoferum (strain 4B)Imported
Taxonomic identifieri862719 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeAzospirillum
Proteomesi
  • UP000005667 Componenti: Plasmid AZO_p5

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei41N6-(pyridoxal phosphate)lysineUniRule annotation1

Structurei

3D structure databases

ProteinModelPortaliG7ZIB6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini248 – 374Ala_racemase_CInterPro annotationAdd BLAST127

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK01775
OMAiISHFACA
OrthoDBiPOG091H022F

Family and domain databases

Gene3Di2.40.37.10, 1 hit
3.20.20.10, 1 hit
HAMAPiMF_01201 Ala_racemase, 1 hit
InterProiView protein in InterPro
IPR000821 Ala_racemase
IPR009006 Ala_racemase/Decarboxylase_C
IPR011079 Ala_racemase_C
IPR001608 Ala_racemase_N
IPR020622 Ala_racemase_pyridoxalP-BS
IPR029066 PLP-binding_barrel
PfamiView protein in Pfam
PF00842 Ala_racemase_C, 1 hit
PF01168 Ala_racemase_N, 1 hit
PRINTSiPR00992 ALARACEMASE
SMARTiView protein in SMART
SM01005 Ala_racemase_C, 1 hit
SUPFAMiSSF50621 SSF50621, 1 hit
SSF51419 SSF51419, 1 hit
TIGRFAMsiTIGR00492 alr, 1 hit
PROSITEiView protein in PROSITE
PS00395 ALANINE_RACEMASE, 1 hit

Sequencei

Sequence statusi: Complete.

G7ZIB6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSDLNPRAG AILTVDLGAV VANWTQLRDR VAPAECSAVV KADAYGLGVA
60 70 80 90 100
RVVPALAAAG CRTFVVAQFE EALAVRRALK PVAPEAQEEV QIFSLGGLPA
110 120 130 140 150
GCEGDFIANR ILPVLNHLGE IAAWRAFATS RGEVLPAVIH IDTGMNRLGL
160 170 180 190 200
GPDELDELAG HPEWLEGIDV RYWMTHLACA DEFDSPMTGE QLDRFRAALA
210 220 230 240 250
RLPKAKASFA NSSGIFHGKD HHFDLARPGC ALYGVNPTPH LPNPMLGTVR
260 270 280 290 300
LDARLLQVRN CTVPMTVGYG AAHKVTGPAR IATIGVGYAD GYMRALGGKG
310 320 330 340 350
HVFVDGVAAP IVGRISMDLI TIDVTGLPES VAHAGRMVEL IGPNRPVDTV
360 370
AAEGGTIGYE ILTSLGRRYH RVYVGG
Length:376
Mass (Da):39,888
Last modified:January 25, 2012 - v1
Checksum:i8E0ACB81F1EF1CB5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ311873 Genomic DNA Translation: CBS91280.1
RefSeqiWP_014250102.1, NC_016624.1

Genome annotation databases

EnsemblBacteriaiCBS91280; CBS91280; AZOLI_p50284
KEGGiali:AZOLI_p50284

Similar proteinsi

Entry informationi

Entry nameiG7ZIB6_AZOL4
AccessioniPrimary (citable) accession number: G7ZIB6
Entry historyiIntegrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: March 28, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, PlasmidImported, Reference proteomeImported

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