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Protein

Thymidine kinase

Gene

HPL003_23840

Organism
Paenibacillus terrae (strain HPL-003)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. thymidine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciPTER985665:GHT3-4808-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Ordered Locus Names:HPL003_23840Imported
OrganismiPaenibacillus terrae (strain HPL-003)Imported
Taxonomic identifieri985665 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus
ProteomesiUP000005876 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857.
OMAiVITGPMY.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G7VSJ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTGRITIIT GPMFSEKSGE LIRRCQKLIQ YGHRKVVAYK PAEDNRYAKD
60 70 80 90 100
EIVSRIGYRL PAISIPKKLT DELVQQILEE TKDADVVAFD EVQFFSRHIM
110 120 130 140 150
TLVEELAYCG KHVIADGLNL DYRGKEFGYV GGLLAMADDI EKLASFCAVC
160 170 180 190
GSSEAVYTQR MVNGKPSTVG PIVMIGDSEA YEPRCRDCFI PPHKVNCD
Length:198
Mass (Da):22,143
Last modified:January 25, 2012 - v1
Checksum:i3444DEC2E63E2E2A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003107 Genomic DNA. Translation: AET61486.1.
RefSeqiWP_014282178.1. NC_016641.1.
YP_005077709.1. NC_016641.1.

Genome annotation databases

EnsemblBacteriaiAET61486; AET61486; HPL003_23840.
KEGGipta:HPL003_23840.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003107 Genomic DNA. Translation: AET61486.1.
RefSeqiWP_014282178.1. NC_016641.1.
YP_005077709.1. NC_016641.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAET61486; AET61486; HPL003_23840.
KEGGipta:HPL003_23840.

Phylogenomic databases

KOiK00857.
OMAiVITGPMY.

Enzyme and pathway databases

BioCyciPTER985665:GHT3-4808-MONOMER.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Complete sequence of Paenibacillus terrae HPL-003."
    Shin S.H., Kim S., Kim J.Y.
    Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HPL-003Imported.
  2. Shin S.H., Kim S., Kim J.Y.
    Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HPL-003.

Entry informationi

Entry nameiG7VSJ6_PAETH
AccessioniPrimary (citable) accession number: G7VSJ6
Entry historyi
Integrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: April 29, 2015
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.