Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

G7VK75

- G7VK75_LEUME

UniProt

G7VK75 - G7VK75_LEUME

Protein

Thymidine kinase

Gene

tdk

Organism
Leuconostoc mesenteroides subsp. mesenteroides J18
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 18 (01 Oct 2014)
      Sequence version 1 (25 Jan 2012)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei98 – 981Proton acceptorUniRule annotation
    Metal bindingi155 – 1551ZincUniRule annotation
    Metal bindingi158 – 1581ZincUniRule annotation
    Metal bindingi192 – 1921ZincUniRule annotation
    Metal bindingi195 – 1951ZincUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi20 – 278ATPUniRule annotation
    Nucleotide bindingi97 – 1004ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. thymidine kinase activity Source: UniProtKB-HAMAP
    3. zinc ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, Nucleotide-binding, ZincUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciLMES1107880:GLFP-1595-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    Name:tdkUniRule annotation
    ORF Names:MI1_07745Imported
    OrganismiLeuconostoc mesenteroides subsp. mesenteroides J18Imported
    Taxonomic identifieri1107880 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLeuconostocaceaeLeuconostoc
    ProteomesiUP000005875: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotationSAAS annotation

    Structurei

    3D structure databases

    ProteinModelPortaliG7VK75.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.UniRule annotation

    Phylogenomic databases

    KOiK00857.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00124. Thymidine_kinase.
    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view]
    PANTHERiPTHR11441. PTHR11441. 1 hit.
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G7VK75-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFSIARKHSK NMAQLFFEYG AMSSGKSIEI LKVAHNYESQ GRKVLLMTPI    50
    MDTRAGVGVV ASRIGLSREA VAVQPEDDLY HLIKGMKDDH LAVVLIDEAQ 100
    FLAAKQVDQL AYVVDHLNIP VMTFGLKQDA FNHLFEGSKR LIELADKLEE 150
    MKTICSFCGK KATTQLRIVD GKPQREGAQV FIGGDEAYIP TCRHHWFKPD 200
    LDKITEMFPV K 211
    Length:211
    Mass (Da):23,725
    Last modified:January 25, 2012 - v1
    Checksum:i6E579FC33BC1DE40
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003101 Genomic DNA. Translation: AET30991.1.
    RefSeqiYP_005174957.1. NC_016805.1.

    Genome annotation databases

    EnsemblBacteriaiAET30991; AET30991; MI1_07745.
    GeneIDi11807969.
    KEGGilmm:MI1_07745.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003101 Genomic DNA. Translation: AET30991.1 .
    RefSeqi YP_005174957.1. NC_016805.1.

    3D structure databases

    ProteinModelPortali G7VK75.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AET30991 ; AET30991 ; MI1_07745 .
    GeneIDi 11807969.
    KEGGi lmm:MI1_07745.

    Phylogenomic databases

    KOi K00857.

    Enzyme and pathway databases

    BioCyci LMES1107880:GLFP-1595-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00124. Thymidine_kinase.
    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view ]
    PANTHERi PTHR11441. PTHR11441. 1 hit.
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete Genome Sequence of Leuconostoc mesenteroides subsp. mesenteroides Strain J18, Isolated from Kimchi."
      Jung J.Y., Lee S.H., Lee S.H., Jeon C.O.
      J. Bacteriol. 194:730-731(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: J18Imported.

    Entry informationi

    Entry nameiG7VK75_LEUME
    AccessioniPrimary (citable) accession number: G7VK75
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 25, 2012
    Last sequence update: January 25, 2012
    Last modified: October 1, 2014
    This is version 18 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3