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G7VK75

- G7VK75_LEUME

UniProt

G7VK75 - G7VK75_LEUME

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Protein

Thymidine kinase

Gene
tdk, MI1_07745
Organism
Leuconostoc mesenteroides subsp. mesenteroides J18
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei98 – 981Proton acceptor By similarityUniRule annotation
Metal bindingi155 – 1551Zinc By similarityUniRule annotation
Metal bindingi158 – 1581Zinc By similarityUniRule annotation
Metal bindingi192 – 1921Zinc By similarityUniRule annotation
Metal bindingi195 – 1951Zinc By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi20 – 278ATP By similarityUniRule annotation
Nucleotide bindingi97 – 1004ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations, Nucleotide-binding, ZincUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciLMES1107880:GLFP-1595-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
ORF Names:MI1_07745Imported
OrganismiLeuconostoc mesenteroides subsp. mesenteroides J18Imported
Taxonomic identifieri1107880 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLeuconostocaceaeLeuconostoc
ProteomesiUP000005875: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliG7VK75.

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G7VK75-1 [UniParc]FASTAAdd to Basket

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MFSIARKHSK NMAQLFFEYG AMSSGKSIEI LKVAHNYESQ GRKVLLMTPI    50
MDTRAGVGVV ASRIGLSREA VAVQPEDDLY HLIKGMKDDH LAVVLIDEAQ 100
FLAAKQVDQL AYVVDHLNIP VMTFGLKQDA FNHLFEGSKR LIELADKLEE 150
MKTICSFCGK KATTQLRIVD GKPQREGAQV FIGGDEAYIP TCRHHWFKPD 200
LDKITEMFPV K 211
Length:211
Mass (Da):23,725
Last modified:January 25, 2012 - v1
Checksum:i6E579FC33BC1DE40
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003101 Genomic DNA. Translation: AET30991.1.
RefSeqiYP_005174957.1. NC_016805.1.

Genome annotation databases

EnsemblBacteriaiAET30991; AET30991; MI1_07745.
GeneIDi11807969.
KEGGilmm:MI1_07745.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003101 Genomic DNA. Translation: AET30991.1 .
RefSeqi YP_005174957.1. NC_016805.1.

3D structure databases

ProteinModelPortali G7VK75.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AET30991 ; AET30991 ; MI1_07745 .
GeneIDi 11807969.
KEGGi lmm:MI1_07745.

Phylogenomic databases

KOi K00857.

Enzyme and pathway databases

BioCyci LMES1107880:GLFP-1595-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of Leuconostoc mesenteroides subsp. mesenteroides Strain J18, Isolated from Kimchi."
    Jung J.Y., Lee S.H., Lee S.H., Jeon C.O.
    J. Bacteriol. 194:730-731(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: J18Imported.

Entry informationi

Entry nameiG7VK75_LEUME
AccessioniPrimary (citable) accession number: G7VK75
Entry historyi
Integrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: September 3, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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