Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

G7UWB8 (G7UWB8_PSEUP) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047 EMBL AER55231.1
Ordered Locus Names:DSC_02890 EMBL AER55231.1
OrganismPseudoxanthomonas spadix (strain BD-a59) [Complete proteome] [HAMAP] EMBL AER55231.1
Taxonomic identifier1045855 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaePseudoxanthomonas

Protein attributes

Sequence length318 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain116 – 310195ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding142 – 19756ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2641Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2771Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2771Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2791Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
G7UWB8 [UniParc].

Last modified January 25, 2012. Version 1.
Checksum: D3CEC5A62E49295C

FASTA31833,873
        10         20         30         40         50         60 
MSAPSFPPPR NTDPAAFGRV AVLMGGTSSE REVSLNSGRN VLEALQARGV QAHAVDGLPA 

        70         80         90        100        110        120 
LLEQIRAGAI DRVFNILHGG DGENGVLQGL LSALKVPFTG PGVLGSALTL DKIRTKQVWI 

       130        140        150        160        170        180 
ASGLPTPAFR RIRRGDDLRA AAAELGLPVF VKPSTEGSSV GVFRVLAEQD LQPAIDFAAG 

       190        200        210        220        230        240 
YDGELLIEQM VQGEEYTVGI LDGIALPSIR IVPAGAWYDY HAKYIAEDTQ YLCPGLSGQE 

       250        260        270        280        290        300 
EAQIRQLSLA AFESAACSGW GRVDVMRDVS RGLQLIEVNT APGMTSHSLV PKAARQAGIG 

       310 
FEELCWRILE STFQARPA 

« Hide

References

[1]"Complete Genome Sequence of the BTEX-Degrading Bacterium Pseudoxanthomonas spadix BD-a59."
Lee S.H., Jin H.M., Lee H.J., Kim J.M., Jeon C.O.
J. Bacteriol. 194:544-544(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BD-a59 EMBL AER55231.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003093 Genomic DNA. Translation: AER55231.1.
RefSeqYP_004929272.1. NC_016147.2.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAER55231; AER55231; DSC_02890.
GeneID11375093.
KEGGpsd:DSC_02890.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

BioCycPSPA1045855:GH5V-382-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG7UWB8_PSEUP
AccessionPrimary (citable) accession number: G7UWB8
Entry history
Integrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: June 11, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)