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G7UGQ6 (G7UGQ6_PANAN) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyltransferase component of pyruvate dehydrogenase complex RuleBase RU361137

EC=2.3.1.12 RuleBase RU361137
Gene names
ORF Names:PAGR_g3454 EMBL AER33946.1
OrganismPantoea ananatis PA13 [Complete proteome] EMBL AER33946.1
Taxonomic identifier1095774 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePantoea

Protein attributes

Sequence length634 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2 By similarity. RuleBase RU361137

Catalytic activity

Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine. RuleBase RU361137

Cofactor

Binds 1 lipoyl cofactor covalently By similarity. RuleBase RU361137

Binds 2 lipoyl cofactors covalently By similarity. RuleBase RU361137

Binds 3 lipoyl cofactors covalently By similarity. RuleBase RU361137

Subunit structure

Forms a 24-polypeptide structural core with octahedral symmetry By similarity. RuleBase RU361137

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU361137

Contains 3 lipoyl-binding domains. RuleBase RU361137

Ontologies

Sequences

Sequence LengthMass (Da)Tools
G7UGQ6 [UniParc].

Last modified January 25, 2012. Version 1.
Checksum: 44B954C309569083

FASTA63466,259
        10         20         30         40         50         60 
MAIEIKVPDI GSDEVEVTEI LVKVGDKVEA EQSLITVEGD KASMEVPSPQ AGVVKEIKIA 

        70         80         90        100        110        120 
TGDKVETGSL IMMFDAEGAA EAAPAAAEEK KADAAPAPAA AAATASKEVA VPDIGGDEVE 

       130        140        150        160        170        180 
VTEILVKVGD KVEAEQSLIV VEGDKASMEV PAPFAGVVKE ITIATGDKVS TGSAIMVFEA 

       190        200        210        220        230        240 
EGAAPASDAK PEVKEEAASA PAAAAGAKDV NVPDIGGDEV EVTEILVKVG DKVEAEQSLI 

       250        260        270        280        290        300 
VVEGDKASME VPAPFAGIVK ELKVATGDKV STGSLIMVFE VEGAAPAAPA AAKQEAAPAP 

       310        320        330        340        350        360 
AAKSEAKAAA APAAAKTESK GEFAENDAYV HATPVIRRLA REFGVNLAKV KGTGRKGRIL 

       370        380        390        400        410        420 
KEDVQAYVKD AVKRAEAAPA AASGGGLPGM LPWPKVDFSK FGEVEEVELG RIQKISGANL 

       430        440        450        460        470        480 
SRNWVMIPHV THFDKTDITE LEAFRKQQNA EAEKRKLDVK YTPVVFIMKA VAAALEQMPR 

       490        500        510        520        530        540 
FNSSLSEDAQ KLTLKKYINI GVAVDTPNGL VVPVFKDVNK KGITELSREL MAISKKARDG 

       550        560        570        580        590        600 
KLTAGDMQGG CFTISSLGGL GTTHFAPIVN APEVAILGVS KSAMEPVWNG KEFAPRLMMP 

       610        620        630 
ISLSFDHRVI DGADGARFIT IIGNMLSDIR RLVM 

« Hide

References

[1]"Complete Genome Sequence of the Rice Pathogen Pantoea ananatis Strain PA13."
Choi O., Lim J.Y., Seo Y.S., Hwang I., Kim J.
J. Bacteriol. 194:531-531(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: PA13 EMBL AER33946.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003085 Genomic DNA. Translation: AER33946.1.
RefSeqYP_005994166.1. NC_017554.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAER33946; AER33946; PAGR_g3454.
GeneID12585134.
KEGGpaq:PAGR_g3454.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00627.

Enzyme and pathway databases

BioCycPANA1095774:GLIA-3533-MONOMER.

Family and domain databases

Gene3D3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR006256. AcTrfase_Pyrv_DH_cplx.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 3 hits.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 3 hits.
TIGRFAMsTIGR01348. PDHac_trf_long. 1 hit.
PROSITEPS50968. BIOTINYL_LIPOYL. 3 hits.
PS00189. LIPOYL. 3 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG7UGQ6_PANAN
AccessionPrimary (citable) accession number: G7UGQ6
Entry history
Integrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: July 9, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)