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G7UGQ6

- G7UGQ6_PANAN

UniProt

G7UGQ6 - G7UGQ6_PANAN

Protein

Acetyltransferase component of pyruvate dehydrogenase complex

Gene

PAGR_g3454

Organism
Pantoea ananatis PA13
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (25 Jan 2012)
      Previous versions | rss
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    Functioni

    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.UniRule annotation

    Catalytic activityi

    Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine.

    Cofactori

    Binds 1 lipoyl cofactor covalently.UniRule annotation
    Binds 2 lipoyl cofactors covalently.UniRule annotation
    Binds 3 lipoyl cofactors covalently.UniRule annotation

    GO - Molecular functioni

    1. dihydrolipoyllysine-residue acetyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    AcyltransferaseUniRule annotation, Transferase

    Keywords - Biological processi

    GlycolysisUniRule annotation

    Keywords - Ligandi

    PyruvateImported

    Enzyme and pathway databases

    BioCyciPANA1095774:GLIA-3533-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.12UniRule annotation)
    Gene namesi
    ORF Names:PAGR_g3454Imported
    OrganismiPantoea ananatis PA13Imported
    Taxonomic identifieri1095774 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePantoea
    ProteomesiUP000005872: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. pyruvate dehydrogenase complex Source: InterPro

    Interactioni

    Subunit structurei

    Forms a 24-polypeptide structural core with octahedral symmetry.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Contains 3 lipoyl-binding domains.UniRule annotation

    Keywords - Domaini

    LipoylUniRule annotationSAAS annotation

    Phylogenomic databases

    KOiK00627.

    Family and domain databases

    Gene3Di3.30.559.10. 1 hit.
    4.10.320.10. 1 hit.
    InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
    IPR001078. 2-oxoacid_DH_actylTfrase.
    IPR006256. AcTrfase_Pyrv_DH_cplx.
    IPR000089. Biotin_lipoyl.
    IPR023213. CAT-like_dom.
    IPR004167. E3-bd.
    IPR011053. Single_hybrid_motif.
    [Graphical view]
    PfamiPF00198. 2-oxoacid_dh. 1 hit.
    PF00364. Biotin_lipoyl. 3 hits.
    PF02817. E3_binding. 1 hit.
    [Graphical view]
    SUPFAMiSSF47005. SSF47005. 1 hit.
    SSF51230. SSF51230. 3 hits.
    TIGRFAMsiTIGR01348. PDHac_trf_long. 1 hit.
    PROSITEiPS50968. BIOTINYL_LIPOYL. 3 hits.
    PS00189. LIPOYL. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G7UGQ6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAIEIKVPDI GSDEVEVTEI LVKVGDKVEA EQSLITVEGD KASMEVPSPQ    50
    AGVVKEIKIA TGDKVETGSL IMMFDAEGAA EAAPAAAEEK KADAAPAPAA 100
    AAATASKEVA VPDIGGDEVE VTEILVKVGD KVEAEQSLIV VEGDKASMEV 150
    PAPFAGVVKE ITIATGDKVS TGSAIMVFEA EGAAPASDAK PEVKEEAASA 200
    PAAAAGAKDV NVPDIGGDEV EVTEILVKVG DKVEAEQSLI VVEGDKASME 250
    VPAPFAGIVK ELKVATGDKV STGSLIMVFE VEGAAPAAPA AAKQEAAPAP 300
    AAKSEAKAAA APAAAKTESK GEFAENDAYV HATPVIRRLA REFGVNLAKV 350
    KGTGRKGRIL KEDVQAYVKD AVKRAEAAPA AASGGGLPGM LPWPKVDFSK 400
    FGEVEEVELG RIQKISGANL SRNWVMIPHV THFDKTDITE LEAFRKQQNA 450
    EAEKRKLDVK YTPVVFIMKA VAAALEQMPR FNSSLSEDAQ KLTLKKYINI 500
    GVAVDTPNGL VVPVFKDVNK KGITELSREL MAISKKARDG KLTAGDMQGG 550
    CFTISSLGGL GTTHFAPIVN APEVAILGVS KSAMEPVWNG KEFAPRLMMP 600
    ISLSFDHRVI DGADGARFIT IIGNMLSDIR RLVM 634
    Length:634
    Mass (Da):66,259
    Last modified:January 25, 2012 - v1
    Checksum:i44B954C309569083
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003085 Genomic DNA. Translation: AER33946.1.
    RefSeqiYP_005994166.1. NC_017554.1.

    Genome annotation databases

    EnsemblBacteriaiAER33946; AER33946; PAGR_g3454.
    GeneIDi12585134.
    KEGGipaq:PAGR_g3454.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003085 Genomic DNA. Translation: AER33946.1 .
    RefSeqi YP_005994166.1. NC_017554.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AER33946 ; AER33946 ; PAGR_g3454 .
    GeneIDi 12585134.
    KEGGi paq:PAGR_g3454.

    Phylogenomic databases

    KOi K00627.

    Enzyme and pathway databases

    BioCyci PANA1095774:GLIA-3533-MONOMER.

    Family and domain databases

    Gene3Di 3.30.559.10. 1 hit.
    4.10.320.10. 1 hit.
    InterProi IPR003016. 2-oxoA_DH_lipoyl-BS.
    IPR001078. 2-oxoacid_DH_actylTfrase.
    IPR006256. AcTrfase_Pyrv_DH_cplx.
    IPR000089. Biotin_lipoyl.
    IPR023213. CAT-like_dom.
    IPR004167. E3-bd.
    IPR011053. Single_hybrid_motif.
    [Graphical view ]
    Pfami PF00198. 2-oxoacid_dh. 1 hit.
    PF00364. Biotin_lipoyl. 3 hits.
    PF02817. E3_binding. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47005. SSF47005. 1 hit.
    SSF51230. SSF51230. 3 hits.
    TIGRFAMsi TIGR01348. PDHac_trf_long. 1 hit.
    PROSITEi PS50968. BIOTINYL_LIPOYL. 3 hits.
    PS00189. LIPOYL. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete Genome Sequence of the Rice Pathogen Pantoea ananatis Strain PA13."
      Choi O., Lim J.Y., Seo Y.S., Hwang I., Kim J.
      J. Bacteriol. 194:531-531(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PA13Imported.

    Entry informationi

    Entry nameiG7UGQ6_PANAN
    AccessioniPrimary (citable) accession number: G7UGQ6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 25, 2012
    Last sequence update: January 25, 2012
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3