G7TTN9 (G7TTN9_VIBCL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Mannose-6-phosphate isomerase RuleBase RU000611
EC=5.3.1.8 RuleBase RU000611

Gene names

ORF Names:

Vch1786_I1320 EMBL AET26921.1

Organism

Vibrio cholerae O1 str. 2010EL-1786 EMBL AET26921.1

Taxonomic identifier

914149 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio › Vibrio cholerae › Vibrio cholerae O1

Protein attributes

Sequence length	406 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-mannose 6-phosphate = D-fructose 6-phosphate. RuleBase RU000611
Cofactor	Binds 1 zinc ion per subunit By similarity. RuleBase RU000611
Sequence similarities	Belongs to the mannose-6-phosphate isomerase type 1 family. RuleBase RU004189

Ontologies

Keywords
Ligand	Zinc RuleBase RU000611
Molecular function	Isomerase RuleBase RU000611 EMBL AET26921.1
Gene Ontology (GO)
Biological_process	GDP-mannose biosynthetic process Inferred from electronic annotation. Source: InterPro carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	mannose-6-phosphate isomerase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	G7TTN9 [UniParc]. Last modified January 25, 2012. Version 1. Checksum: 6232E02153D25252	FASTA	406	45,234
	10 20 30 40 50 60 MTQIPTQDAA LPEAVFFPMT NPIQNYAWGS KTALQQLFEL ENPNDDPQAE LWMGAHPNGC 70 80 90 100 110 120 SGIAINGKIV QLSDFIAQNP NLILGEYTAR QFGELPYLFK ILAAEKALSI QVHPNKQQAE 130 140 150 160 170 180 RGFAQEEQLG IALTAAQRNY KDPNHKPELV YALTEYQAMN GFRANQEILN YFIELSIDEI 190 200 210 220 230 240 QPLVNVFQSN PTEQGLRDFF SGLLSLQGEA KNRALEALMA QAKQIDLPLF QLIVELENQY 250 260 270 280 290 300 PNDIGLFAPL MLNVITLQPG EAMFLDAETP HAYLHGTGLE IMANSDNVLR AGLTPKYMDI 310 320 330 340 350 360 DELVACTQFK HKPLEQLRLK PEVIEGCEQY PIPVADFKFA IIPPTTQQTI GVKSAEVVLP 370 380 390 400 LDSSMILRHA NGEQCLVRKG QSVFIPAYAE QYTIECNGRV ARAFSA

References

[1]	Balajee S.A., Besser J., Fields P., Frace A.M., Freeman M., Govil D., Humphrys M., Neuhaus E., Olsen-Rasmussen M., Ribot E., Rowe L., Sammons S., Seenu S., Talkington D., Tang K., Tarr C., Gerner-Smidt P. Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 2010EL-1786 EMBL AET26921.1.
[2]	"Comparative Genomics of Vibrio cholerae from Haiti, Asia, and Africa." Reimer A.R., Domselaar G.V., Stroika S., Walker M., Kent H., Tarr C., Talkington D., Rowe L., Olsen-Rasmussen M., Frace M., Sammons S., Dahourou G.A., Boncy J., Smith A.M., Mabon P., Petkau A., Graham M., Gilmour M.W., Gerner-Smidt P. Emerg. Infect. Dis. 17:2113-2121(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 2010EL-1786 EMBL AET26921.1.
[3]	V. cholerae Outbreak Genomics Task Force Reimer A.R., Van Domselaar G., Stroika S., Walker M., Kent H., Tarr C., Talkington D., Rowe L., Olsen-Rasmussen M., Frace M., Sammons S., Dahourou G.A., Boncy J., Smith A.M., Mabon P., Petkau A., Graham M., Gilmour M.W., Gerner-Smidt P. Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 2010EL-1786 EMBL AET26921.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP003069 Genomic DNA. Translation: AET26921.1.
RefSeq	YP_004937475.1. NC_016445.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AET26921; AET26921; Vch1786_I1320.
GeneID	11461139.
KEGG	vce:Vch1786_I1320.
Phylogenomic databases
KO	K01809.
Family and domain databases
Gene3D	2.60.120.10. 3 hits.
InterPro	IPR001250. Man6P_Isoase-1. IPR016305. Mannose-6-P_Isomerase. IPR018050. Pmannose_isomerase-type1_CS. IPR014710. RmlC-like_jellyroll. IPR011051. RmlC_Cupin. [Graphical view]
PANTHER	PTHR10309. PTHR10309. 1 hit.
Pfam	PF01238. PMI_typeI. 1 hit. [Graphical view]
PIRSF	PIRSF001480. Mannose-6-phosphate_isomerase. 1 hit.
PRINTS	PR00714. MAN6PISMRASE.
SUPFAM	SSF51182. RmlC_like_cupin. 1 hit.
TIGRFAMs	TIGR00218. manA. 1 hit.
PROSITE	PS00965. PMI_I_1. 1 hit. PS00966. PMI_I_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G7TTN9_VIBCL

Accession

Primary (citable) accession number: G7TTN9

Entry history

Integrated into UniProtKB/TrEMBL:	January 25, 2012
Last sequence update:	January 25, 2012
Last modified:	April 3, 2013
This is version 10 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)