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G7TTA1 (G7TTA1_VIBCL) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylamine--glycine ligase HAMAP-Rule MF_00138
EC=6.3.4.13 HAMAP-Rule MF_00138
Alternative name(s):
GARS HAMAP-Rule MF_00138
Glycinamide ribonucleotide synthetase HAMAP-Rule MF_00138
Phosphoribosylglycinamide synthetase HAMAP-Rule MF_00138
Gene names
Name:purD HAMAP-Rule MF_00138
ORF Names:Vch1786_I2558 EMBL AET28121.1
OrganismVibrio cholerae O1 str. 2010EL-1786 EMBL AET28121.1
Taxonomic identifier914149 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio ›

Protein attributes

Sequence length429 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)-(5-phospho-D-ribosyl)glycinamide. HAMAP-Rule MF_00138

Cofactor

Binds (magnesium or manganese,ion) per subunit By similarity. HAMAP-Rule MF_00138

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2. HAMAP-Rule MF_00138

Sequence similarities

Belongs to the GARS family. HAMAP-Rule MF_00138

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00138

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain109 – 316208ATP-grasp By similarity HAMAP-Rule MF_00138
Nucleotide binding135 – 19662ATP By similarity HAMAP-Rule MF_00138

Sites

Metal binding2861Magnesium or manganese By similarity HAMAP-Rule MF_00138
Metal binding2881Magnesium or manganese By similarity HAMAP-Rule MF_00138

Sequences

Sequence LengthMass (Da)Tools
G7TTA1 [UniParc].

Last modified January 25, 2012. Version 1.
Checksum: D30ABCCF8F7A6FFC

FASTA42945,336
        10         20         30         40         50         60 
MQVLIIGSGG REHALAWKVA QNPQVDTIYV APGNAGTALE HKVQNVNIGI TDIPALVAFA 

        70         80         90        100        110        120 
QDKAIELTIV GPEAPLVIGV VDAFRAAGLP IFGPTQGAAQ LEGSKVFTKD FLARHNIPTA 

       130        140        150        160        170        180 
AYANFTEIEP ALAYVREKGA PIVVKADGLA AGKGVIVAMT LQEAEDAIQD MLAGNAFGSA 

       190        200        210        220        230        240 
GSRVVVEEFL DGEEASFIVM VDGENVLPMA TSQDHKRVGD ADTGPNTGGM GAYSPAPVVT 

       250        260        270        280        290        300 
QDVHDRVMRE VIDPTVRGMA AEGNTYTGFL YAGLMIDSTG APKVIEYNCR FGDPETQPIM 

       310        320        330        340        350        360 
MRLQSDLVEL CQAAIAGKLD QVESKWDPRA SIGVVLAAGG YPGDYAKGEV ISGLPTQESA 

       370        380        390        400        410        420 
GQKVFHAGTE TQGDQVVTNG GRVLCATALG NTVLEAQQRA YQLADQIHWN GMFCRRDIGY 


RAIAREQAK

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP003069 Genomic DNA. Translation: AET28121.1.
RefSeqYP_004938675.1. NC_016445.1.

3D structure databases

ProteinModelPortalG7TTA1.
SMRG7TTA1. Positions 1-425.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAET28121; AET28121; Vch1786_I2558.
GeneID11462377.
KEGGvce:Vch1786_I2558.

Phylogenomic databases

KOK01945.

Enzyme and pathway databases

UniPathwayUPA00074; UER00125.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
3.90.600.10. 1 hit.
HAMAPMF_00138. GARS.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR016185. PreATP-grasp_dom.
IPR020561. PRibGlycinamid_synth_ATP-grasp.
IPR000115. PRibGlycinamide_synth.
IPR020560. PRibGlycinamide_synth_C-dom.
IPR020559. PRibGlycinamide_synth_CS.
IPR020562. PRibGlycinamide_synth_N.
IPR011054. Rudment_hybrid_motif.
[Graphical view]
PfamPF01071. GARS_A. 1 hit.
PF02843. GARS_C. 1 hit.
PF02844. GARS_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
SSF51246. Rudmnt_hyb_motif. 1 hit.
TIGRFAMsTIGR00877. purD. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00184. GARS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG7TTA1_VIBCL
AccessionPrimary (citable) accession number: G7TTA1
Entry history
Integrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: May 1, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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