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Protein
Submitted name:

4-aminobutyrate aminotransferase

Gene

gabT

Organism
Escherichia coli (strain 'clone D i14')
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. 4-aminobutyrate transaminase activity Source: InterPro
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. gamma-aminobutyric acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciECOL885275:GJE6-2953-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
4-aminobutyrate aminotransferaseImported
Gene namesi
Name:gabTImported
Ordered Locus Names:i14_2941Imported
OrganismiEscherichia coli (strain 'clone D i14')Imported
Taxonomic identifieri885275 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000005864: Chromosome

Structurei

3D structure databases

ProteinModelPortaliG7RRQ6.
SMRiG7RRQ6. Positions 4-428.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

KOiK07250.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G7RRQ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRMSSNKELM QRRSQAIPRG VGQIHPIFAD RAENCRVWDV EGREYLDFAG
60 70 80 90 100
GIAVLNTGHL HPKVVAAVEA QLKKLSHTCF QVLAYEPYLE LCEIMNQKVP
110 120 130 140 150
GDFAKKTLLV TTGSEAVENA VKIARAATKR SGTIAFSGAY HGRTHYTLAL
160 170 180 190 200
TGKVNPYSAG MGLMPGHVYR ALYPCPLHGI SEDDAIASIH RIFKNDAAPE
210 220 230 240 250
DIAAIVIEPV QGEGGFYAAT PAFMQRLRAL CDEHGIMLIA DEVQSGAGRT
260 270 280 290 300
GTLFAMEQMG VAPDLTTFAK SIAGGFPLAG VTGRAEVMDA VAPGGLGGTY
310 320 330 340 350
AGNPIACVAA LEVLKVFEQE NLLQKANVLG QKLKDGLLAI AEKHPEIGDV
360 370 380 390 400
RGLGAMIAIE LFEDGEHSKP DVKLTAEIVA RARDKGLILL SCGPYYNVLR
410 420
ILVPLTIEDA QIRQGLEIIS QCFAEAKQ
Length:428
Mass (Da):45,988
Last modified:January 25, 2012 - v1
Checksum:iCC74C904792EE1B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002212 Genomic DNA. Translation: AER90406.1.
RefSeqiWP_001242959.1. NC_017652.1.
YP_006155030.1. NC_017652.1.

Genome annotation databases

EnsemblBacteriaiAER90406; AER90406; i14_2941.
GeneIDi12665658.
KEGGielc:i14_2941.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002212 Genomic DNA. Translation: AER90406.1.
RefSeqiWP_001242959.1. NC_017652.1.
YP_006155030.1. NC_017652.1.

3D structure databases

ProteinModelPortaliG7RRQ6.
SMRiG7RRQ6. Positions 4-428.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAER90406; AER90406; i14_2941.
GeneIDi12665658.
KEGGielc:i14_2941.

Phylogenomic databases

KOiK07250.

Enzyme and pathway databases

BioCyciECOL885275:GJE6-2953-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Rates of mutation and host transmission for an Escherichia coli clone over 3 years."
    Reeves P.R., Liu B., Zhou Z., Li D., Guo D., Ren Y., Clabots C., Lan R., Johnson J.R., Wang L.
    PLoS ONE 6:E26907-E26907(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 'clone D i14'Imported.

Entry informationi

Entry nameiG7RRQ6_ECOC1
AccessioniPrimary (citable) accession number: G7RRQ6
Entry historyi
Integrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: February 4, 2015
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.