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G7RQ38

- G7RQ38_ECOC1

UniProt

G7RQ38 - G7RQ38_ECOC1

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Protein

Xylose isomerase

Gene
xylA, i14_4052
Organism
Escherichia coli (strain 'clone D i14')
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotations

Cofactori

Binds 2 magnesium ions per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei101 – 1011 By similarityUniRule annotation
Active sitei104 – 1041 By similarityUniRule annotation
Metal bindingi232 – 2321Magnesium 1 By similarityUniRule annotation
Metal bindingi268 – 2681Magnesium 1 By similarityUniRule annotation
Metal bindingi268 – 2681Magnesium 2 By similarityUniRule annotation
Metal bindingi271 – 2711Magnesium 2 By similarityUniRule annotation
Metal bindingi296 – 2961Magnesium 1 By similarityUniRule annotation
Metal bindingi307 – 3071Magnesium 2 By similarityUniRule annotation
Metal bindingi309 – 3091Magnesium 2 By similarityUniRule annotation
Metal bindingi339 – 3391Magnesium 1 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotations, Xylose metabolismUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciECOL885275:GJE6-4071-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotationImported
Ordered Locus Names:i14_4052Imported
OrganismiEscherichia coli (strain 'clone D i14')Imported
Taxonomic identifieri885275 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000005864: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliG7RQ38.
SMRiG7RQ38. Positions 2-439.

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G7RQ38-1 [UniParc]FASTAAdd to Basket

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MQAYFDQLDR VRYEGSKSSN PLAFRHYNPD ELVLGKRMEE HLRFAACYWH    50
TFCWNGADMF GVGAFNRPWQ QPGEALALAK RKADVAFEFF HKLHVPFYCF 100
HDVDVSPEGA SLKEYINNFA QMVDVLAGKQ EESGVKLLWG TANCFTNPRY 150
GAGAATNPDP EVFSWAATQV VTAMEATHKL GGENYVLWGG REGYETLLNT 200
DLRQEREQLG RFMQMVVEHK HKIGFQGTLL IEPKPQEPTK HQYDYDAATV 250
YGFLKQFGLE KEIKLNIEAN HATLAGHSFH HEIATAIALG LFGSVDANRG 300
DAQLGWDTDQ FPNSVEENAL VMYEILKAGG FTTGGLNFDA KVRRQSTDKY 350
DLFYGHIGAM DTMALALKIA ARMIEDGELD KRIAQRYSGW NSELGQQILK 400
GQMSLADLAK YAQEHNLSPV HQSGRQEQLE NLVNHYLFDK 440
Length:440
Mass (Da):49,719
Last modified:January 25, 2012 - v1
Checksum:i6E21039B6EC0561F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002212 Genomic DNA. Translation: AER91497.1.
RefSeqiYP_006156121.1. NC_017652.1.

Genome annotation databases

EnsemblBacteriaiAER91497; AER91497; i14_4052.
GeneIDi12666776.
KEGGielc:i14_4052.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002212 Genomic DNA. Translation: AER91497.1 .
RefSeqi YP_006156121.1. NC_017652.1.

3D structure databases

ProteinModelPortali G7RQ38.
SMRi G7RQ38. Positions 2-439.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AER91497 ; AER91497 ; i14_4052 .
GeneIDi 12666776.
KEGGi elc:i14_4052.

Phylogenomic databases

KOi K01805.

Enzyme and pathway databases

BioCyci ECOL885275:GJE6-4071-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Rates of Mutation and Host Transmission for an Escherichia coli Clone over 3 Years."
    Reeves P.R., Liu B., Zhou Z., Li D., Guo D., Ren Y., Clabots C., Lan R., Johnson J.R., Wang L.
    PLoS ONE 6:E26907-E26907(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 'clone D i14'.

Entry informationi

Entry nameiG7RQ38_ECOC1
AccessioniPrimary (citable) accession number: G7RQ38
Entry historyi
Integrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: June 11, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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