Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

G7RM21

- G7RM21_ECOC1

UniProt

G7RM21 - G7RM21_ECOC1

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Acyl carrier protein

Gene

acpP

Organism
Escherichia coli (strain 'clone D i14')
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Carrier of the growing fatty acid chain in fatty acid biosynthesis.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei37 – 371PhosphopantetheineImported

GO - Molecular functioni

  1. ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Fatty acid biosynthesisUniRule annotationSAAS annotation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciECOL885275:GJE6-1262-MONOMER.
UniPathwayiUPA00094.

Names & Taxonomyi

Protein namesi
Recommended name:
Acyl carrier proteinUniRule annotation
Short name:
ACPUniRule annotation
Gene namesi
Name:acpPUniRule annotationImported
Ordered Locus Names:i14_1248Imported
OrganismiEscherichia coli (strain 'clone D i14')Imported
Taxonomic identifieri885275 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000005864: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei37 – 371O-(pantetheine 4'-phosphoryl)serineUniRule annotation

Post-translational modificationi

4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.UniRule annotation
4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.UniRule annotation

Keywords - PTMi

PhosphopantetheineUniRule annotation, PhosphoproteinUniRule annotationSAAS annotation

Proteomic databases

PRIDEiG7RM21.

Interactioni

Protein-protein interaction databases

DIPiDIP-60690N.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4IHFX-ray2.10G/H/I/J/K/L1-78[»]
4IHGX-ray2.89G/H/I/J/K/L1-78[»]
4IHHX-ray2.13G/H/I/J/K/L1-78[»]
ProteinModelPortaliG7RM21.
SMRiG7RM21. Positions 2-78.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 acyl carrier domain.UniRule annotation
Contains acyl carrier domain.SAAS annotation

Phylogenomic databases

KOiK02078.

Family and domain databases

Gene3Di1.10.1200.10. 1 hit.
HAMAPiMF_01217. Acyl_carrier.
InterProiIPR003231. Acyl_carrier.
IPR009081. Acyl_carrier_prot-like.
IPR006162. PPantetheine_attach_site.
[Graphical view]
PfamiPF00550. PP-binding. 1 hit.
[Graphical view]
ProDomiPD000887. PD000887. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF47336. SSF47336. 1 hit.
TIGRFAMsiTIGR00517. acyl_carrier. 1 hit.
PROSITEiPS50075. ACP_DOMAIN. 1 hit.
PS00012. PHOSPHOPANTETHEINE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G7RM21-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSTIEERVKK IIGEQLGVKQ EEVTNNASFV EDLGADSLDT VELVMALEEE
60 70
FDTEIPDEEA EKITTVQAAI DYINGHQA
Length:78
Mass (Da):8,640
Last modified:January 25, 2012 - v1
Checksum:i41FCFC39D45BFEA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002212 Genomic DNA. Translation: AER88748.1.
RefSeqiYP_006153372.1. NC_017652.1.

Genome annotation databases

EnsemblBacteriaiAER88748; AER88748; i14_1248.
GeneIDi12663967.
KEGGielc:i14_1248.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002212 Genomic DNA. Translation: AER88748.1 .
RefSeqi YP_006153372.1. NC_017652.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4IHF X-ray 2.10 G/H/I/J/K/L 1-78 [» ]
4IHG X-ray 2.89 G/H/I/J/K/L 1-78 [» ]
4IHH X-ray 2.13 G/H/I/J/K/L 1-78 [» ]
ProteinModelPortali G7RM21.
SMRi G7RM21. Positions 2-78.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-60690N.

Proteomic databases

PRIDEi G7RM21.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AER88748 ; AER88748 ; i14_1248 .
GeneIDi 12663967.
KEGGi elc:i14_1248.

Phylogenomic databases

KOi K02078.

Enzyme and pathway databases

UniPathwayi UPA00094 .
BioCyci ECOL885275:GJE6-1262-MONOMER.

Family and domain databases

Gene3Di 1.10.1200.10. 1 hit.
HAMAPi MF_01217. Acyl_carrier.
InterProi IPR003231. Acyl_carrier.
IPR009081. Acyl_carrier_prot-like.
IPR006162. PPantetheine_attach_site.
[Graphical view ]
Pfami PF00550. PP-binding. 1 hit.
[Graphical view ]
ProDomi PD000887. PD000887. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF47336. SSF47336. 1 hit.
TIGRFAMsi TIGR00517. acyl_carrier. 1 hit.
PROSITEi PS50075. ACP_DOMAIN. 1 hit.
PS00012. PHOSPHOPANTETHEINE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Rates of mutation and host transmission for an Escherichia coli clone over 3 years."
    Reeves P.R., Liu B., Zhou Z., Li D., Guo D., Ren Y., Clabots C., Lan R., Johnson J.R., Wang L.
    PLoS ONE 6:E26907-E26907(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 'clone D i14'Imported.
  2. "Chasing acyl carrier protein through a catalytic cycle of lipid A production."
    Masoudi A., Raetz C.R., Zhou P., Pemble C.W.
    Nature 505:422-426(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) IN COMPLEX WITH PHOSPHOPANTETHEINE.

Entry informationi

Entry nameiG7RM21_ECOC1
AccessioniPrimary (citable) accession number: G7RM21
Entry historyi
Integrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: October 29, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteomeImported

External Data

Dasty 3