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G7RM21 (G7RM21_ECOC1) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Acyl carrier protein HAMAP-Rule MF_01217

Short name=ACP HAMAP-Rule MF_01217
Gene names
Name:acpP HAMAP-Rule MF_01217 EMBL AER88748.1
Ordered Locus Names:i14_1248 EMBL AER88748.1
OrganismEscherichia coli (strain 'clone D i14') [Complete proteome] [HAMAP] EMBL AER88748.1
Taxonomic identifier885275 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length78 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Carrier of the growing fatty acid chain in fatty acid biosynthesis By similarity. HAMAP-Rule MF_01217 RuleBase RU003545

Pathway

Lipid metabolism; fatty acid biosynthesis. HAMAP-Rule MF_01217 RuleBase RU003545 SAAS SAAS003231

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01217 SAAS SAAS003231.

Post-translational modification

4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group By similarity. HAMAP-Rule MF_01217

4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS By similarity. RuleBase RU003545

Sequence similarities

Contains 1 acyl carrier domain. HAMAP-Rule MF_01217 RuleBase RU003545

Contains acyl carrier domain. SAAS SAAS003231

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Binding site371Phosphopantetheine PDB 4IHG PDB 4IHH

Amino acid modifications

Modified residue371O-(pantetheine 4'-phosphoryl)serine By similarity HAMAP-Rule MF_01217

Sequences

Sequence LengthMass (Da)Tools
G7RM21 [UniParc].

Last modified January 25, 2012. Version 1.
Checksum: 41FCFC39D45BFEA1

FASTA788,640
        10         20         30         40         50         60 
MSTIEERVKK IIGEQLGVKQ EEVTNNASFV EDLGADSLDT VELVMALEEE FDTEIPDEEA 

        70 
EKITTVQAAI DYINGHQA 

« Hide

References

« Hide 'large scale' references
[1]"Rates of Mutation and Host Transmission for an Escherichia coli Clone over 3 Years."
Reeves P.R., Liu B., Zhou Z., Li D., Guo D., Ren Y., Clabots C., Lan R., Johnson J.R., Wang L.
PLoS ONE 6:E26907-E26907(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 'clone D i14'.
[2]"Chasing acyl carrier protein through a catalytic cycle of lipid A production."
Masoudi A., Raetz C.R., Zhou P., Pemble C.W.
Nature 505:422-426(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) IN COMPLEX WITH PHOSPHOPANTETHEINE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002212 Genomic DNA. Translation: AER88748.1.
RefSeqYP_006153372.1. NC_017652.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4IHFX-ray2.10G/H/I/J/K/L1-78[»]
4IHGX-ray2.89G/H/I/J/K/L1-78[»]
4IHHX-ray2.13G/H/I/J/K/L1-78[»]
ProteinModelPortalG7RM21.
SMRG7RM21. Positions 2-78.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-60690N.

Proteomic databases

PRIDEG7RM21.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAER88748; AER88748; i14_1248.
GeneID12663967.
KEGGelc:i14_1248.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK02078.

Enzyme and pathway databases

BioCycECOL885275:GJE6-1262-MONOMER.
UniPathwayUPA00094.

Family and domain databases

Gene3D1.10.1200.10. 1 hit.
HAMAPMF_01217. Acyl_carrier.
InterProIPR003231. Acyl_carrier.
IPR009081. Acyl_carrier_prot-like.
IPR006162. PPantetheine_attach_site.
[Graphical view]
PfamPF00550. PP-binding. 1 hit.
[Graphical view]
ProDomPD000887. PD000887. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF47336. SSF47336. 1 hit.
TIGRFAMsTIGR00517. acyl_carrier. 1 hit.
PROSITEPS50075. ACP_DOMAIN. 1 hit.
PS00012. PHOSPHOPANTETHEINE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG7RM21_ECOC1
AccessionPrimary (citable) accession number: G7RM21
Entry history
Integrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: July 9, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)