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G7QT21 (G7QT21_MYCBI) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Cobyric acid synthase HAMAP-Rule MF_00028
Gene names
Name:cobQ1 EMBL AET17551.1
Synonyms:cobQ HAMAP-Rule MF_00028
ORF Names:BCGMEX_0262c EMBL AET17551.1
OrganismMycobacterium bovis BCG str. Mexico EMBL AET17551.1
Taxonomic identifier717522 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex ›

Protein attributes

Sequence length494 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH2 groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation By similarity. HAMAP-Rule MF_00028 SAAS SAAS017929

Pathway

Cofactor biosynthesis; adenosylcobalamin biosynthesis. HAMAP-Rule MF_00028 SAAS SAAS017929

Sequence similarities

Belongs to the CobB/CobQ family. CobQ subfamily. HAMAP-Rule MF_00028

Contains 1 GATase cobBQ-type domain. HAMAP-Rule MF_00028 SAAS SAAS017929

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain253 – 432180GATase cobBQ-type By similarity HAMAP-Rule MF_00028

Sites

Active site3341Nucleophile By similarity HAMAP-Rule MF_00028
Active site4241 By similarity HAMAP-Rule MF_00028

Sequences

Sequence LengthMass (Da)Tools
G7QT21 [UniParc].

Last modified January 25, 2012. Version 1.
Checksum: D97858AA7BB56CA2

FASTA49452,135
        10         20         30         40         50         60 
MSGLLVAGTT SDAGKSAVTA GLCRALARRG VRVAPFKAQN MSNNSMVCRG PDGTGVEIGR 

        70         80         90        100        110        120 
AQWVQALAAR TTPEAAMNPV LLKPASDHRS HVVLMGKPWG EVASSSWCAG RRALAEAACR 

       130        140        150        160        170        180 
AFDALAARYD VVVAEGAGSP AEINLRAGDY VNMGLARHAG LPTIVVGDID RGGVFAAFLG 

       190        200        210        220        230        240 
TVALLAAEDQ ALVAGFVVNK FRGDSDLLAP GLRDLERVTG RRVYGTLPWH PDLWLDSEDA 

       250        260        270        280        290        300 
LDLQGRRAAG TGARRVAVVR LPRISNFTDV DALGLEPDLD VVFASDPRAL DDADLIVLPG 

       310        320        330        340        350        360 
TRATIADLAW LRARDLDRAL LVHVAAGKPL LGICGGFQML GRVIRDPYGI EGPGGQVTEV 

       370        380        390        400        410        420 
EGLGLLDVET AFSPHKVLRL PRGEGLGVPA SGYEIHHGRI TRGDTAEEFL GGARDGPVFG 

       430        440        450        460        470        480 
TMWHGSLEGD ALREAFLRET LGLAPSGSCF LAARERRLDL LGDLVERHLD VDALLNLARH 

       490 
GCPPTLPFLA PGAP

« Hide

References

[1]"Genomic and proteomic analyses of Mycobacterium bovis BCG Mexico 1931 reveal a diverse immunogenic repertoire against tuberculosis infection."
Orduna P., Cevallos M.A., de Leon S.P., Arvizu A., Hernandez-Gonzalez I.L., Mendoza-Hernandez G., Lopez-Vidal Y.
BMC Genomics 12:493-493(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Mexico EMBL AET17551.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002095 Genomic DNA. Translation: AET17551.1.
RefSeqYP_005169734.1. NC_016804.1.

3D structure databases

ProteinModelPortalG7QT21.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAET17551; AET17551; BCGMEX_0262c.
GeneID11808526.
KEGGmbm:BCGMEX_0262c.

Phylogenomic databases

KOK02232.

Enzyme and pathway databases

BioCycMBOV717522:GJXR-265-MONOMER.
UniPathwayUPA00148.

Family and domain databases

HAMAPMF_00028. CobQ.
InterProIPR017929. CobB/CobQ_GATase.
IPR002586. CobQ/CobB/MinD/ParA_Nub-bd_dom.
IPR004459. CobQ_synth.
IPR011698. GATase_3.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF01656. CbiA. 1 hit.
PF07685. GATase_3. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00313. cobQ. 1 hit.
PROSITEPS51274. GATASE_COBBQ. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG7QT21_MYCBI
AccessionPrimary (citable) accession number: G7QT21
Entry history
Integrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: May 29, 2013
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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