G7QEZ8 (G7QEZ8_LEPII) Unreviewed, UniProtKB/TrEMBL
Last modified
April 3, 2013.
Version 12.
History...
Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Submitted name: D-alanine--D-alanine ligase EMBL AER02996.1 | ||
| Gene names |
| ||
| Organism | Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain IPAV) [Complete proteome] [HAMAP] | ||
| Taxonomic identifier | 573825 [NCBI] | ||
| Taxonomic lineage | Bacteria › Spirochaetes › Spirochaetales › Leptospiraceae › Leptospira › ![]() |
Protein attributes
| Sequence length | 374 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Cell wall formation By similarity. SAAS SAAS005905 |
| Catalytic activity | ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. SAAS SAAS005905 |
| Cofactor | Binds 2 magnesium or manganese ions per subunit By similarity. SAAS SAAS005905 |
| Pathway | Cell wall biogenesis; peptidoglycan biosynthesis. SAAS SAAS005905 |
| Subcellular location | Cytoplasm By similarity SAAS SAAS005905. |
| Sequence similarities | Contains 1 ATP-grasp domain. SAAS SAAS005905 |
Ontologies
| Keywords | |
|---|---|
| Biological process | Cell shape Cell wall biogenesis/degradation SAAS SAAS005905 Peptidoglycan synthesis SAAS SAAS005905 |
| Cellular component | Cytoplasm SAAS SAAS005905 |
| Ligand | ATP-binding SAAS SAAS005905 Magnesium SAAS SAAS005905 Manganese SAAS SAAS005905 Metal-binding SAAS SAAS005905 Nucleotide-binding |
| Molecular function | Ligase SAAS SAAS005905 EMBL AER02996.1 |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological_process | peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway regulation of cell shapeInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular_component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular_function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW D-alanine-D-alanine ligase activityInferred from electronic annotation. Source: InterPro metal ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequences
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References
| [1] | "Comparative proteogenomic analysis of the Leptospira interrogans virulence-attenuated strain IPAV against the pathogenic strain 56601." Zhong Y., Chang X., Cao X.J., Zhang Y., Zheng H., Zhu Y., Cai C., Cui Z., Zhang Y., Li Y.Y., Jiang X.G., Zhao G.P., Wang S., Li Y., Zeng R., Li X., Guo X.K. Cell Res. 21:1210-1229(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IPAV EMBL AER02996.1. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP001221 Genomic DNA. Translation: AER02996.1. |
| RefSeq | YP_005988979.1. NC_017551.1. |
3D structure databases | |
| ProteinModelPortal | G7QEZ8. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | AER02996; AER02996; LIF_A2207. |
| GeneID | 12580660. |
| KEGG | lie:LIF_A2207. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| KO | K01921. |
Enzyme and pathway databases | |
| UniPathway | UPA00219. |
Family and domain databases | |
| Gene3D | 3.30.1490.20. 1 hit. 3.30.470.20. 2 hits. |
| InterPro | IPR011761. ATP-grasp. IPR013815. ATP_grasp_subdomain_1. IPR013816. ATP_grasp_subdomain_2. IPR005905. D_ala_D_ala. IPR011095. Dala_Dala_lig_C. IPR016185. PreATP-grasp_dom. [Graphical view] |
| PANTHER | PTHR23132. PTHR23132. 1 hit. |
| Pfam | PF07478. Dala_Dala_lig_C. 1 hit. [Graphical view] |
| SUPFAM | SSF52440. PreATP-grasp-like. 1 hit. |
| PROSITE | PS50975. ATP_GRASP. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | G7QEZ8_LEPII | ||||||||
| Accession | Primary (citable) accession number: G7QEZ8 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

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