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G7QEZ8

- G7QEZ8_LEPII

UniProt

G7QEZ8 - G7QEZ8_LEPII

Protein
Submitted name:

D-alanine--D-alanine ligase

Gene

LIF_A2207

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain IPAV)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 16 (01 Oct 2014)
      Sequence version 1 (25 Jan 2012)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. D-alanine-D-alanine ligase activity Source: InterPro
    3. metal ion binding Source: InterPro

    GO - Biological processi

    1. peptidoglycan biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    LigaseImported

    Enzyme and pathway databases

    BioCyciLINT573825:GLFK-2201-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    D-alanine--D-alanine ligaseImported
    Gene namesi
    Ordered Locus Names:LIF_A2207Imported
    OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain IPAV)Imported
    Taxonomic identifieri573825 [NCBI]
    Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira
    ProteomesiUP000005628: Chromosome 1

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: InterPro

    Structurei

    3D structure databases

    ProteinModelPortaliG7QEZ8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    KOiK01921.
    OMAiFLEVNPL.

    Family and domain databases

    Gene3Di3.30.1490.20. 1 hit.
    3.30.470.20. 2 hits.
    InterProiIPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    [Graphical view]
    PANTHERiPTHR23132. PTHR23132. 1 hit.
    PfamiPF07478. Dala_Dala_lig_C. 1 hit.
    [Graphical view]
    PROSITEiPS50975. ATP_GRASP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G7QEZ8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNKMTPTVLV YADLHEFEGN FPEIYKQEWE SKKSVDAILE LLNEVGESIE    50
    LVVTPNELLE KLKCYCDLDF SKRPVIFHLM EGFCSRNRES LIPAVAELFG 100
    FPHTGSDSYS QNVSLDKNLT RIFAQSIGVP VASGFWIRSK DVLFKELLQL 150
    ECNSEIKKRF SFSKGNELNL KNFSFPAFIK PAGEGSSLGI GEKNIIYSFE 200
    ELNTLLSEAP EIFFPYLLEE YLTGNEYTIS VIGSATFGYK VSSAGRLILR 250
    EDLKVEDVYG EKTKSKSIMP ETLVFDCPKD LEVIIQQQSV LFCESLGTSG 300
    PARLDWKLDS LGNPFFLEMN LTPGLSPFYS TFPICYRHSL GDEKNLFQEI 350
    LKIARLDFET DRFLYSKNKI RNLI 374
    Length:374
    Mass (Da):42,571
    Last modified:January 25, 2012 - v1
    Checksum:iF3944060831D47BA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001221 Genomic DNA. Translation: AER02996.1.
    RefSeqiYP_005988979.1. NC_017551.1.

    Genome annotation databases

    EnsemblBacteriaiAER02996; AER02996; LIF_A2207.
    GeneIDi12580660.
    KEGGilie:LIF_A2207.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001221 Genomic DNA. Translation: AER02996.1 .
    RefSeqi YP_005988979.1. NC_017551.1.

    3D structure databases

    ProteinModelPortali G7QEZ8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AER02996 ; AER02996 ; LIF_A2207 .
    GeneIDi 12580660.
    KEGGi lie:LIF_A2207.

    Phylogenomic databases

    KOi K01921.
    OMAi FLEVNPL.

    Enzyme and pathway databases

    BioCyci LINT573825:GLFK-2201-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1490.20. 1 hit.
    3.30.470.20. 2 hits.
    InterProi IPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    [Graphical view ]
    PANTHERi PTHR23132. PTHR23132. 1 hit.
    Pfami PF07478. Dala_Dala_lig_C. 1 hit.
    [Graphical view ]
    PROSITEi PS50975. ATP_GRASP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comparative proteogenomic analysis of the Leptospira interrogans virulence-attenuated strain IPAV against the pathogenic strain 56601."
      Zhong Y., Chang X., Cao X.J., Zhang Y., Zheng H., Zhu Y., Cai C., Cui Z., Zhang Y., Li Y.Y., Jiang X.G., Zhao G.P., Wang S., Li Y., Zeng R., Li X., Guo X.K.
      Cell Res. 21:1210-1229(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: IPAVImported.

    Entry informationi

    Entry nameiG7QEZ8_LEPII
    AccessioniPrimary (citable) accession number: G7QEZ8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 25, 2012
    Last sequence update: January 25, 2012
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3