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Protein

Lipase

Gene

LIPN

Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei173NucleophileUniRule annotation1
Active sitei344Charge relay systemUniRule annotation1
Active sitei373Charge relay systemUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
Biological processLipid degradationUniRule annotation, Lipid metabolism

Protein family/group databases

MEROPSiS33.018.

Names & Taxonomyi

Protein namesi
Recommended name:
LipaseUniRule annotation
Gene namesi
Name:LIPNImported
ORF Names:EGM_18181Imported
OrganismiMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)Imported
Taxonomic identifieri9541 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000009130 Componenti: Chromosome 9

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500350234221 – 398LipaseSequence analysisAdd BLAST378

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini79 – 379AB hydrolase-1InterPro annotationAdd BLAST301

Sequence similaritiesi

Belongs to the AB hydrolase superfamily. Lipase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00550000074328.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiView protein in InterPro
IPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
IPR025483. Lipase_euk.
PfamiView protein in Pfam
PF00561. Abhydrolase_1. 1 hit.
PIRSFiPIRSF000862. Steryl_ester_lip. 1 hit.
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

G7PDH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMWLLLTTTC LICGTLNVGG FLDLENEVNP EVWMNTSEII IYNGYPSEEY
60 70 80 90 100
EVTTEDGYIL LVNRIPYGRR HIRSTGPRPV VYMQHALFAD NAYWLENYAN
110 120 130 140 150
GSLGFLLADA GYDVWMGNSR GNTWSRRHKT LSETDEKFWA FSFDEMAKYD
160 170 180 190 200
LPGVIDFIVN KTGQEKLYFI GHSLGTTIGF VAFSTMPELA QRIKMNFALG
210 220 230 240 250
PVISFKYPTG IFTSFFLLPN SIIKAVFGTK GFFLEDKKKK IPSTKICNNK
260 270 280 290 300
ILWLICSEFM SLWAGSNKKN MNQSRMDVYM SHAPTGSSIQ NILHIKQLYQ
310 320 330 340 350
SDEFRAYDWG NEADNMKHYN QSHPPIYDLT AMKVPTAIWA GGHDVLVTPQ
360 370 380 390
DVARILPQIK SLHYFKLLPD WNHFDFVWGL DAPQRMYSEI IALMKAYS
Length:398
Mass (Da):45,651
Last modified:January 25, 2012 - v1
Checksum:iE1D8B16F668328A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIA01071906 Genomic DNA. No translation available.
AQIA01071907 Genomic DNA. No translation available.
AQIA01071908 Genomic DNA. No translation available.
CM001284 Genomic DNA. Translation: EHH64856.1.
RefSeqiXP_005565948.1. XM_005565891.2.

Genome annotation databases

EnsembliENSMFAT00000001153; ENSMFAP00000026971; ENSMFAG00000044901.
GeneIDi102137951.
KEGGimcf:102137951.

Similar proteinsi

Entry informationi

Entry nameiG7PDH4_MACFA
AccessioniPrimary (citable) accession number: G7PDH4
Entry historyiIntegrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: March 28, 2018
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported