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Protein

Guanine nucleotide-binding protein subunit gamma

Gene

GNG2

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransducerUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Guanine nucleotide-binding protein subunit gammaUniRule annotation
Gene namesi
Name:GNG2Imported
ORF Names:EGK_18187Imported
OrganismiMacaca mulatta (Rhesus macaque)
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

PTM / Processingi

Keywords - PTMi

LipoproteinUniRule annotation

Interactioni

Subunit structurei

G proteins are composed of 3 units; alpha, beta and gamma.UniRule annotation

Structurei

3D structure databases

SMRiG7MXW9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 71G protein gammaInterPro annotationAdd BLAST67

Sequence similaritiesi

Belongs to the G protein gamma family.UniRule annotation

Phylogenomic databases

eggNOGiKOG4119. Eukaryota.
ENOG41122JF. LUCA.
KOiK07826.
OMAiETSEMAS.
TreeFamiTF319909.

Family and domain databases

CDDicd00068. GGL. 1 hit.
InterProiView protein in InterPro
IPR015898. G-protein_gamma-like_dom.
IPR036284. GGL_sf.
IPR001770. Gprotein-gamma.
PANTHERiPTHR13809. PTHR13809. 1 hit.
PfamiView protein in Pfam
PF00631. G-gamma. 1 hit.
PRINTSiPR00321. GPROTEING.
SMARTiView protein in SMART
SM00224. GGL. 1 hit.
SUPFAMiSSF48670. SSF48670. 1 hit.
PROSITEiView protein in PROSITE
PS50058. G_PROTEIN_GAMMA. 1 hit.

Sequencei

Sequence statusi: Complete.

G7MXW9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASNNTASIA QARKLVEQLK MEANIDRIKV SKAAADLMAY CEAHAKEDPL
60 70
LTPVPASENP FREKKFFCAI L
Length:71
Mass (Da):7,850
Last modified:November 30, 2016 - v1
Checksum:iEDB74E4135E7A37A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JU320544 mRNA. Translation: AFE64300.1.
JU473092 mRNA. Translation: AFH29896.1.
JV045013 mRNA. Translation: AFI35084.1.
CM001259 Genomic DNA. Translation: EHH27876.1.
RefSeqiNP_001177839.1. NM_001190910.1.
XP_014999125.1. XM_015143639.1.
XP_014999126.1. XM_015143640.1.
XP_014999127.1. XM_015143641.1.
UniGeneiMmu.18125.

Genome annotation databases

GeneIDi710000.
KEGGimcc:710000.

Similar proteinsi

Entry informationi

Entry nameiG7MXW9_MACMU
AccessioniPrimary (citable) accession number: G7MXW9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2016
Last sequence update: November 30, 2016
Last modified: October 25, 2017
This is version 11 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)