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Protein
Submitted name:

Uncharacterized protein

Gene

EGK_16549

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
ORF Names:EGK_16549Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 79SH3InterPro annotationAdd BLAST77
Domaini113 – 301Rho-GAPInterPro annotationAdd BLAST189
Domaini333 – 428SH2InterPro annotationAdd BLAST96
Domaini632 – 726SH2InterPro annotationAdd BLAST95

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili514 – 562Sequence analysisAdd BLAST49

Keywords - Domaini

Coiled coilSequence analysis, SH2 domainPROSITE-ProRule annotation, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4637. Eukaryota.
ENOG410XP6R. LUCA.

Family and domain databases

CDDicd09930. SH2_cSH2_p85_like. 1 hit.
cd09942. SH2_nSH2_p85_like. 1 hit.
cd11910. SH3_PI3K_p85alpha. 1 hit.
Gene3Di1.10.555.10. 1 hit.
3.30.505.10. 2 hits.
InterProiView protein in InterPro
IPR032498. PI3K_P85_iSH2.
IPR035591. PI3K_p85alpha_SH3.
IPR035020. PI3kinase_P85_cSH2.
IPR035022. PI3kinase_P85_nSH2.
IPR001720. PI3kinase_P85_p55.
IPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
IPR000980. SH2.
IPR036860. SH2_dom_sf.
IPR036028. SH3-like_dom_sf.
IPR001452. SH3_domain.
PANTHERiPTHR10155. PTHR10155. 1 hit.
PfamiView protein in Pfam
PF16454. PI3K_P85_iSH2. 1 hit.
PF00620. RhoGAP. 1 hit.
PF00017. SH2. 2 hits.
PRINTSiPR00401. SH2DOMAIN.
SMARTiView protein in SMART
SM00324. RhoGAP. 1 hit.
SM00252. SH2. 2 hits.
SM00326. SH3. 1 hit.
SUPFAMiSSF48350. SSF48350. 1 hit.
SSF50044. SSF50044. 1 hit.
SSF55550. SSF55550. 2 hits.
PROSITEiView protein in PROSITE
PS50238. RHOGAP. 1 hit.
PS50001. SH2. 2 hits.
PS50002. SH3. 1 hit.

Sequencei

Sequence statusi: Complete.

G7MU74-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAEGYQYRA LYDYKKEREE DIDLHLGDIL TVNKGSLVAL GFSDGQEARP
60 70 80 90 100
EEIGWLNGYN ETTGERGDFP GTYVEYIGRK KISPPTPKPR PPRPLPVAPG
110 120 130 140 150
SSKTEADVEQ QALTLPDLAE QFAPPDVAPP LLIKLVEAIE KKGLECSTLY
160 170 180 190 200
RTQSSGNLAE LRQLLDCDTA SVDLEMIDVH ILADAFKRYL LDLPNPVIPA
210 220 230 240 250
AVYSEMISLA QEVQSSEEYI QLLKKLIRSP SIPHQYWLTL QYLLKHFFKL
260 270 280 290 300
SQTSSKNLLN ARVLSEIFSP MLFRFSAASS DNTENLIKVI EILISTEWNE
310 320 330 340 350
RQPAPALPPK PPKPTTVANN GMNNNMSLQD AEWYWGDISR EEVNEKLRDT
360 370 380 390 400
ADGTFLVRDA STKMHGDYTL TLRKGGNNKL IKIFHRDGKY GFSDPLTFNS
410 420 430 440 450
VVELINHYRN ESLAQYNPKL DVKLLYPVSK YQQDQVVKED NIEAVGKKLH
460 470 480 490 500
EYNTQFQEKS GEYDRLYEEY TRTSQEIQMK RTAIEAFNET IKIFEEQCQT
510 520 530 540 550
QERYSKEYIE KFKREGNEKE IQRIMHNYDK LKSRISEIID SRRRLEEDLK
560 570 580 590 600
KQAAEYREID KRMNSIKPDL IQLRKTRDQY LMWLTQKGVR QKKLNEWLGN
610 620 630 640 650
ENTEENFLSC LPSQYSLVED DEDLPHHDEK TWNVGSSNRN KAENLLRGKR
660 670 680 690 700
DGTFLVRESS KQGCYACSVV VDGEVKHCVI NKTATGYGFA EPYNLYSSLK
710 720 730
ELVLHYQHTS LVQHNDSLNV TLAYPVYAQQ RR
Length:732
Mass (Da):84,377
Last modified:January 25, 2012 - v1
Checksum:iB6996F84184204DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM001258 Genomic DNA. Translation: EHH26543.1.

Similar proteinsi

Entry informationi

Entry nameiG7MU74_MACMU
AccessioniPrimary (citable) accession number: G7MU74
Entry historyiIntegrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: November 22, 2017
This is version 26 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)