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Protein

Alanine racemase

Gene

BJ6T_57440

Organism
Bradyrhizobium japonicum USDA 6
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei59 – 591Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei157 – 1571SubstrateUniRule annotation
Active sitei278 – 2781Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei331 – 3311Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciBJAP1037409:GL9L-5741-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
ORF Names:BJ6T_57440Imported
OrganismiBradyrhizobium japonicum USDA 6Imported
Taxonomic identifieri1037409 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
ProteomesiUP000005663 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei59 – 591N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliG7DI05.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G7DI05-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASDPKMIPQ SGLLSAEANQ AAALAAYGGV LTVDLDAIIA NWRKLEKTAV
60 70 80 90 100
PAECSAVIKA DAYGCGAAQV SRALSKAGCK TFFVATIEEA RTVREAVPEA
110 120 130 140 150
AIYVLGGYFQ NTGEHYAKIN CRPVIGDLNE LAEWDVFCRR TGWTGGAAVH
160 170 180 190 200
IDTGMNRLGL TLADAQAIIP RINAGDHGIT LVMSHLVSAE QLNSPVNAKQ
210 220 230 240 250
LATFRGIASE FSGVPAALAN SSGIFLGAPF QFDLVRPGAA LYGVNPTPEA
260 270 280 290 300
DNPMQPVVDL KARIVQTRNV ERGETVGYGG TWTARRPTKL AIIAVGYADG
310 320 330 340 350
YFRAASSNDG TRGAEVVVAG KRCPVAGRVS MDLIAIDITD LPPNAARRGH
360 370 380 390 400
MVTLLGEGIT VDELAHHFGT IGYEVLTSLG RRYARVYKGG NEVEPLVKPE
410 420
PPPTAEQPPS PPPIQQPASP PPLPS
Length:425
Mass (Da):44,825
Last modified:January 25, 2012 - v1
Checksum:i2546D3881846A7BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012206 Genomic DNA. Translation: BAL10999.1.
RefSeqiWP_014495815.1. NZ_AXAV01000001.1.
YP_005610587.1. NC_017249.1.

Genome annotation databases

EnsemblBacteriaiBAL10999; BAL10999; BJ6T_57440.
KEGGibju:BJ6T_57440.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012206 Genomic DNA. Translation: BAL10999.1.
RefSeqiWP_014495815.1. NZ_AXAV01000001.1.
YP_005610587.1. NC_017249.1.

3D structure databases

ProteinModelPortaliG7DI05.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAL10999; BAL10999; BJ6T_57440.
KEGGibju:BJ6T_57440.

Phylogenomic databases

KOiK01775.

Enzyme and pathway databases

UniPathwayiUPA00042; UER00497.
BioCyciBJAP1037409:GL9L-5741-MONOMER.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete Genome Sequence of the Soybean Symbiont Bradyrhizobium japonicum Strain USDA6T."
    Kaneko T., Maita S., Hirakawa H., Uchiike N., Minamisawa K., Watanabe A., Sato S.
    Genes (Basel) 2:763-787(2011)
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: USDA 6Imported.

Entry informationi

Entry nameiG7DI05_BRAJP
AccessioniPrimary (citable) accession number: G7DI05
Entry historyi
Integrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: April 29, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.