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Protein

D-alanine--D-alanine ligase

Gene

BJ6T_28280

Organism
Bradyrhizobium japonicum USDA 6
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cell wall formation.SAAS annotation

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

Cofactori

Protein has several cofactor binding sites:
  • Mg2+SAAS annotation
  • Mn2+SAAS annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseSAAS annotationImported
Biological processCell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciBJAP1037409:G1H8Q-2788-MONOMER
UniPathwayiUPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
D-alanine--D-alanine ligaseSAAS annotation (EC:6.3.2.4SAAS annotation)
Gene namesi
ORF Names:BJ6T_28280Imported
OrganismiBradyrhizobium japonicum USDA 6Imported
Taxonomic identifieri1037409 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi
  • UP000005663 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi1037409.BJ6T_28280

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini127 – 320ATP-graspInterPro annotationAdd BLAST194

Sequence similaritiesi

Belongs to the D-alanine--D-alanine ligase family.SAAS annotation

Phylogenomic databases

eggNOGiCOG1181 LUCA
KOiK01921
OrthoDBiPOG091H00GT

Family and domain databases

Gene3Di3.30.1490.20, 1 hit
InterProiView protein in InterPro
IPR011761 ATP-grasp
IPR013815 ATP_grasp_subdomain_1
IPR011095 Dala_Dala_lig_C
IPR011127 Dala_Dala_lig_N
IPR016185 PreATP-grasp_dom_sf
PfamiView protein in Pfam
PF07478 Dala_Dala_lig_C, 1 hit
PF01820 Dala_Dala_lig_N, 1 hit
SUPFAMiSSF52440 SSF52440, 1 hit
PROSITEiView protein in PROSITE
PS50975 ATP_GRASP, 1 hit

Sequencei

Sequence statusi: Complete.

G7DDW0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRITILFGGS NRERLVSVAS AQALHQALPE ADLWWWDVED KVHVVQSKQL
60 70 80 90 100
LEHARPFEDE FKPGTSGIPL GQALDRAKTE GRVLVLGLHG GRAENGELQV
110 120 130 140 150
MCEARGVPFT GSGSASSHLA FDKIAAKHFA ALGGVTPPAN VALDEIDEAF
160 170 180 190 200
AEYGRLIAKP ARDGSSYGLI FVNARQDLVA VRNAAKHEDY VIEPYIAGVE
210 220 230 240 250
ATCGVLERTD GSIISLPPIE IIPGEGNFDY AAKYLLKSTQ EICPGRFAPE
260 270 280 290 300
ITAALKEQAM LAHRAMSCTG YSRSDFIVSD RGLIYLETNT LPGLTKSSLY
310 320
PKALKAEGIE FVDFLRGLVE LAGRDVRK
Length:328
Mass (Da):35,577
Last modified:January 25, 2012 - v1
Checksum:i8BE21D8D1ED4E931
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012206 Genomic DNA Translation: BAL08106.1
RefSeqiWP_014492961.1, NZ_KI421485.1

Genome annotation databases

EnsemblBacteriaiBAL08106; BAL08106; BJ6T_28280
GeneIDi29265909
KEGGibju:BJ6T_28280
PATRICifig|1037409.3.peg.2853

Similar proteinsi

Entry informationi

Entry nameiG7DDW0_BRAJP
AccessioniPrimary (citable) accession number: G7DDW0
Entry historyiIntegrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: April 25, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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