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G7CC99

- G7CC99_MYCTH

UniProt

G7CC99 - G7CC99_MYCTH

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Protein
Submitted name: 3-hydroxyisobutyryl-CoA hydrolase
Gene
KEK_02971
Organism
Mycobacterium thermoresistibile ATCC 19527
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi32 – 321Zinc 1; via pros nitrogenImported
Metal bindingi46 – 461Zinc 2Imported
Metal bindingi83 – 831Zinc 1Imported
Metal bindingi97 – 971Zinc 2; via tele nitrogenImported
Metal bindingi348 – 3481Zinc 2Imported

GO - Molecular functioni

  1. hydrolase activity Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Keywords - Ligandi

Metal-bindingImported, ZincImported

Names & Taxonomyi

Protein namesi
Submitted name:
3-hydroxyisobutyryl-CoA hydrolaseImported
Gene namesi
ORF Names:KEK_02971Imported
OrganismiMycobacterium thermoresistibile ATCC 19527Imported
Taxonomic identifieri1078020 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4HDTX-ray1.60A2-350[»]

Family & Domainsi

Family and domain databases

Gene3Di1.10.12.10. 1 hit.
3.90.226.10. 1 hit.
InterProiIPR029045. ClpP/crotonase-like_dom.
IPR014748. Crontonase_C.
IPR001753. Crotonase_core_superfam.
[Graphical view]
PfamiPF00378. ECH. 1 hit.
[Graphical view]
SUPFAMiSSF52096. SSF52096. 2 hits.

Sequencei

Sequence statusi: Complete.

G7CC99-1 [UniParc]FASTAAdd to Basket

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MTAKNEDVLV NVEGGVGLLT LNRPKAINSL THGMVTTMAE RLAAWENDDS    50
VRAVLLTGAG ERGLCAGGDV VAIYHSAKAD GAEARRFWFD EYRLNAHIGR 100
YPKPYVSIMD GIVMGGGVGV GAHGNVRVVT DTTKMAMPEV GIGFIPDVGG 150
TYLLSRAPGK LGLHAALTGA PFSGADAIVM GFADHYVPHD KIDEFTRAVI 200
ADGVDAALAA HAQEPPASPL AEQRSWIDEC YTGDTVADII AALRAHDAPA 250
AGEAADLIAT RSPIALSVTL ESVRRAAKLQ SLEDTLRQEY RVSCASLKSH 300
DLVEGIRAQL VDKDRNPKWR PATLAEVTEA DVEAYFAPVD PELTFEGETQ 350
Length:350
Mass (Da):37,240
Last modified:January 25, 2012 - v1
Checksum:i03FF93D19FE338E6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AGVE01000017 Genomic DNA. Translation: EHI14362.1.

Genome annotation databases

EnsemblBacteriaiEHI14362; EHI14362; KEK_02971.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AGVE01000017 Genomic DNA. Translation: EHI14362.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4HDT X-ray 1.60 A 2-350 [» ]
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai EHI14362 ; EHI14362 ; KEK_02971 .

Family and domain databases

Gene3Di 1.10.12.10. 1 hit.
3.90.226.10. 1 hit.
InterProi IPR029045. ClpP/crotonase-like_dom.
IPR014748. Crontonase_C.
IPR001753. Crotonase_core_superfam.
[Graphical view ]
Pfami PF00378. ECH. 1 hit.
[Graphical view ]
SUPFAMi SSF52096. SSF52096. 2 hits.
ProtoNeti Search...

Publicationsi

  1. Tuberculosis Structural Genomics Consortium
    Ioerger T.R.
    Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC 19527Imported.
  2. "Crystal structure of a Carnitinyl-CoA dehydratase from Mycobacterium thermoresistibile."
    Seattle Structural Genomics Center for Infectious Disease (SSGCID)
    Abendroth J., Edwards T.E., Sankaran B., Staker B.L.
    Submitted (OCT-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) OF 2-350 IN COMPLEX WITH ZINC.

Entry informationi

Entry nameiG7CC99_MYCTH
AccessioniPrimary (citable) accession number: G7CC99
Entry historyi
Integrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: September 3, 2014
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3

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