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G7B0E0

- G7B0E0_VIBCL

UniProt

G7B0E0 - G7B0E0_VIBCL

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Protein
Submitted name:

GTP pyrophosphokinase

Gene

relA

Organism
Vibrio cholerae HC-32A1
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.UniRule annotation

GO - Molecular functioni

  1. amino acid binding Source: InterPro
  2. GTP diphosphokinase activity Source: UniProtKB-EC
  3. kinase activity Source: UniProtKB-KW

GO - Biological processi

  1. guanosine tetraphosphate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
GTP pyrophosphokinaseImported (EC:2.7.6.5Imported)
Gene namesi
Name:relAImported
ORF Names:VCHC32A1_2784Imported
OrganismiVibrio cholerae HC-32A1Imported
Taxonomic identifieri991956 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Structurei

3D structure databases

ProteinModelPortaliG7B0E0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the relA/spoT family.UniRule annotation

Family and domain databases

Gene3Di3.10.20.30. 1 hit.
InterProiIPR002912. ACT_dom.
IPR012675. Beta-grasp_dom.
IPR004811. RelA/Spo_fam.
IPR007685. RelA_SpoT.
IPR004095. TGS.
IPR012676. TGS-like.
[Graphical view]
PfamiPF04607. RelA_SpoT. 1 hit.
PF02824. TGS. 1 hit.
[Graphical view]
SMARTiSM00954. RelA_SpoT. 1 hit.
[Graphical view]
SUPFAMiSSF81271. SSF81271. 1 hit.
TIGRFAMsiTIGR00691. spoT_relA. 1 hit.
PROSITEiPS51671. ACT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G7B0E0-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MVAVRSAHLN PDQQFELETW IASLTQEGKT AAKLTAVYRD CEQLLAGNPQ
60 70 80 90 100
GPLLLWRGRE MIEILITLSM DRPTLVAALL FPIATSGVLD NESLEEGYGR
110 120 130 140 150
EVVKLIHGVE EMAAIGQLNV TMHGSEASAQ VDNVRRMLLA MVDDFRCVVI
160 170 180 190 200
KLAERICNLR EVKNEPDEVR RVAAKECANI YAPLANRLGI GQLKWEIEDY
210 220 230 240 250
AFRYQQPDTY KQIAKQLSER RIVREQYIRD FVSDLRAEMK QSGINAEVSG
260 270 280 290 300
RPKHIYSIWR KMQKKSLAFD ELFDVRAVRI IADKLQDCYA ALGIVHTKYK
310 320 330 340 350
HLPNEFDDYV ANPKPNGYQS IHTVILGPEG KTIEIQIRTK QMHEESELGV
360 370 380 390 400
AAHWKYKEGS SAARSGYDEK ITWLRKLLDW QEEMSDSGEM LDELRSQVFD
410 420 430 440 450
DRVYAFTPKG DVVDLPMGAT PLDFAYHIHS EVGHRCIGAK VAGRIVPFTH
460 470 480 490 500
KLQMGDQVEI ITAKEPNPSR DWLNPSLGFV HSGRARAKIN AWFRKQSREK
510 520 530 540 550
NLEAGREILE IELAKIGANL KHAEAYALKR FNVNSVDEMY VGIGSGDLRI
560 570 580 590 600
NQIVNHINAL VNKPTAEEED KLALEKLQEN KTLTPNRPHK DAVVVEGVDN
610 620 630 640 650
LMTHLARCCQ PIPGDEIRGY ITQGRGISVH RSDCEQLEEL SLHAPERIID
660 670 680 690 700
TVWGSGFVGS YLLTVRVEAM ERSGLLKDIT TLLANEKVKV ASMKSRSDYK
710 720 730
RQIIIMDFDL EVNNVEALAR VSKRIEQIKD VMLVKRLG
Length:738
Mass (Da):83,566
Last modified:January 25, 2012 - v1
Checksum:i3C0EF2B3910F691F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AGUO01000056 Genomic DNA. Translation: EHH92039.1.

Genome annotation databases

EnsemblBacteriaiEHH92039; EHH92039; VCHC32A1_2784.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AGUO01000056 Genomic DNA. Translation: EHH92039.1 .

3D structure databases

ProteinModelPortali G7B0E0.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai EHH92039 ; EHH92039 ; VCHC32A1_2784 .

Family and domain databases

Gene3Di 3.10.20.30. 1 hit.
InterProi IPR002912. ACT_dom.
IPR012675. Beta-grasp_dom.
IPR004811. RelA/Spo_fam.
IPR007685. RelA_SpoT.
IPR004095. TGS.
IPR012676. TGS-like.
[Graphical view ]
Pfami PF04607. RelA_SpoT. 1 hit.
PF02824. TGS. 1 hit.
[Graphical view ]
SMARTi SM00954. RelA_SpoT. 1 hit.
[Graphical view ]
SUPFAMi SSF81271. SSF81271. 1 hit.
TIGRFAMsi TIGR00691. spoT_relA. 1 hit.
PROSITEi PS51671. ACT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Vibrio Cholerae HC-32A1."
    Eppinger M., Hasan N.A., Sengamalay N., Hine E., Su Q., Daugherty S.C., Young S., Sadzewicz L., Tallon L., Cebula T.A., Ravel J., Colwell R.R.
    Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HC-32A1Imported.

Entry informationi

Entry nameiG7B0E0_VIBCL
AccessioniPrimary (citable) accession number: G7B0E0
Entry historyi
Integrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: October 1, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

External Data

Dasty 3