G5YCR0 (G5YCR0_ECOLX) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Exodeoxyribonuclease 7 small subunit HAMAP-Rule MF_00337
EC=3.1.11.6 HAMAP-Rule MF_00337

Alternative name(s):
Exodeoxyribonuclease VII small subunit HAMAP-Rule MF_00337

Gene names

Name:	xseB HAMAP-Rule MF_00337
ORF Names:	EUOG_00728 EMBL EHF78682.1

Organism

Escherichia coli O104:H4 str. 11-4632 C5 EMBL EHF78682.1

Taxonomic identifier

1068621 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli › Escherichia coli O104:H4

Protein attributes

Sequence length	80 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides By similarity. SAAS SAAS003761 HAMAP-Rule MF_00337
Catalytic activity	Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates. HAMAP-Rule MF_00337 Exonucleolytic cleavage in either 5'- to 3'-or 3'- to 5'-direction to yield nucleoside 5'-phosphates. SAAS SAAS003761
Subunit structure	Heterooligomer composed of large and small subunits By similarity. SAAS SAAS003761 HAMAP-Rule MF_00337
Subcellular location	Cytoplasm By similarity SAAS SAAS003761 HAMAP-Rule MF_00337.
Sequence similarities	Belongs to the XseB family. HAMAP-Rule MF_00337
Caution	The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Ontologies

Keywords
Cellular component	Cytoplasm SAAS SAAS003761 HAMAP-Rule MF_00337
Molecular function	Exonuclease SAAS SAAS003761 HAMAP-Rule MF_00337 Hydrolase Nuclease
Gene Ontology (GO)
Biological_process	DNA catabolic process Inferred from electronic annotation. Source: HAMAP nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell exodeoxyribonuclease VII complex Inferred from electronic annotation. Source: InterPro
Molecular_function	exodeoxyribonuclease VII activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	G5YCR0 [UniParc]. Last modified January 25, 2012. Version 1. Checksum: 8B10380D442CADF4	FASTA	80	8,952
	10 20 30 40 50 60 MPKKNEAPAS FEKALSELEQ IVTRLESGDL PLEEALNEFE RGVQLARQGQ AKLQQAEQRV 70 80 QILLSDNEDA SLTPFTPDNE

References

[1]

"Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011." Grad Y.H., Lipsitch M., Feldgarden M., Arachchi H.M., Cerqueira G.C., Fitzgerald M., Godfrey P., Haas B.J., Murphy C.I., Russ C., Sykes S., Walker B.J., Wortman J.R., Young S., Zeng Q., Abouelleil A., Bochicchio J., Chauvin S. , Desmet T., Gujja S., McCowan C., Montmayeur A., Steelman S., Frimodt-Moller J., Petersen A.M., Struve C., Krogfelt K.A., Bingen E., Weill F.X., Lander E.S., Nusbaum C., Birren B.W., Hung D.T., Hanage W.P. Proc. Natl. Acad. Sci. U.S.A. 109:3065-3070(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 11-4632 C5 EMBL EHF78682.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AFVE01000025 Genomic DNA. Translation: EHF78682.1.
3D structure databases
ProteinModelPortal	G5YCR0.
SMR	G5YCR0. Positions 8-66.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EHF78682; EHF78682; EUOG_00728.
Phylogenomic databases
OMA	APLNDYK.
Family and domain databases
Gene3D	1.10.287.1040. 1 hit.
HAMAP	MF_00337. Exonuc_7_S.
InterPro	IPR003761. Exonuc_VII_S. [Graphical view]
Pfam	PF02609. Exonuc_VII_S. 1 hit. [Graphical view]
PIRSF	PIRSF006488. Exonuc_VII_S. 1 hit.
ProDom	PD028235. Exonuc_VII_S. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF116842. SSF116842. 1 hit.
TIGRFAMs	TIGR01280. xseB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

G5YCR0_ECOLX

Accession

Primary (citable) accession number: G5YCR0

Entry history

Integrated into UniProtKB/TrEMBL:	January 25, 2012
Last sequence update:	January 25, 2012
Last modified:	May 1, 2013
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)