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G5KRT8

- G5KRT8_ECOLX

UniProt

G5KRT8 - G5KRT8_ECOLX

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Protein

4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase

Gene
kduI, i01_03932
Organism
Escherichia coli cloneA_i1
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate By similarity.UniRule annotationSAAS annotations

Catalytic activityi

5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate.UniRule annotationSAAS annotations

Cofactori

Binds 1 zinc ion per subunit By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi196 – 1961Zinc By similarityUniRule annotation
Metal bindingi198 – 1981Zinc By similarityUniRule annotation
Metal bindingi203 – 2031Zinc By similarityUniRule annotation
Metal bindingi245 – 2451Zinc By similarityUniRule annotation

GO - Molecular functioni

  1. 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity Source: UniProtKB-HAMAP
  2. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. pectin catabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Metal-bindingUniRule annotationSAAS annotations, ZincUniRule annotationSAAS annotations

Enzyme and pathway databases

UniPathwayiUPA00545; UER00826.

Names & Taxonomyi

Protein namesi
Recommended name:
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomeraseUniRule annotation (EC:5.3.1.17UniRule annotation)
Alternative name(s):
5-keto-4-deoxyuronate isomerase
DKI isomerase
Gene namesi
Name:kduIUniRule annotation
ORF Names:i01_03932Imported
OrganismiEscherichia coli cloneA_i1Imported
Taxonomic identifieri993513 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Interactioni

Subunit structurei

Homohexamer By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliG5KRT8.
SMRiG5KRT8. Positions 1-277.

Family & Domainsi

Sequence similaritiesi

Belongs to the KduI family.UniRule annotation

Family and domain databases

Gene3Di2.60.120.500. 1 hit.
2.60.120.520. 1 hit.
HAMAPiMF_00687. KduI.
InterProiIPR007045. KduI.
IPR021120. KduI/IolB_isomerase.
IPR027447. KduI_C.
IPR027449. KduI_N.
IPR011051. RmlC_Cupin.
[Graphical view]
PfamiPF04962. KduI. 1 hit.
[Graphical view]
PIRSFiPIRSF006625. KduI. 1 hit.
SUPFAMiSSF51182. SSF51182. 1 hit.

Sequencei

Sequence statusi: Complete.

G5KRT8-1 [UniParc]FASTAAdd to Basket

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MDVRQSIHSA HAKTLDTQGL RNEFLVEKVF VADEYTMVYS HIDRIIVGGI    50
MPVTKTVSVG GEVGKQLGVS YFLERRELGV INIGGAGTIT VDGQCYEIGH 100
RDALYVGKGA KEVVFASIDT ATPAKFYYNC APAHTTYPTK KVTPDEVSPV 150
TLGDNLTSNR RTINKYFVPD VLETCQLSMG LTELAPGNLW NTMPCHTHER 200
RMEVYFYFNM DDDACVFHMM GQPQETRHIV MHNEQAVISP SWSIHSGVGT 250
KAYTFIWGMV GENQVFDDMD HVAVKDLR 278
Length:278
Mass (Da):31,076
Last modified:January 25, 2012 - v1
Checksum:i7AF3DD98DE74D597
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AEYT01000035 Genomic DNA. Translation: EHG00043.1.

Genome annotation databases

EnsemblBacteriaiEHG00043; EHG00043; i01_03932.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AEYT01000035 Genomic DNA. Translation: EHG00043.1 .

3D structure databases

ProteinModelPortali G5KRT8.
SMRi G5KRT8. Positions 1-277.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai EHG00043 ; EHG00043 ; i01_03932 .

Enzyme and pathway databases

UniPathwayi UPA00545 ; UER00826 .

Family and domain databases

Gene3Di 2.60.120.500. 1 hit.
2.60.120.520. 1 hit.
HAMAPi MF_00687. KduI.
InterProi IPR007045. KduI.
IPR021120. KduI/IolB_isomerase.
IPR027447. KduI_C.
IPR027449. KduI_N.
IPR011051. RmlC_Cupin.
[Graphical view ]
Pfami PF04962. KduI. 1 hit.
[Graphical view ]
PIRSFi PIRSF006625. KduI. 1 hit.
SUPFAMi SSF51182. SSF51182. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Rates of Mutation and Host Transmission for an Escherichia coli Clone over 3 Years."
    Reeves P.R., Liu B., Zhou Z., Li D., Guo D., Ren Y., Clabots C., Lan R., Johnson J.R., Wang L.
    PLoS ONE 6:E26907-E26907(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CloneA_i1Imported.

Entry informationi

Entry nameiG5KRT8_ECOLX
AccessioniPrimary (citable) accession number: G5KRT8
Entry historyi
Integrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: June 11, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

External Data

Dasty 3

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