Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Metallo-beta-lactamase

Gene

SMB-1

Organism
Serratia marcescens
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi90Zinc 1; via tele nitrogenCombined sources1
Metal bindingi92Zinc 1; via pros nitrogenCombined sources1
Metal bindingi94Zinc 2Combined sources1
Metal bindingi95Zinc 2; via tele nitrogenCombined sources1
Binding sitei131Coenzyme MCombined sources1
Metal bindingi168Zinc 1; via tele nitrogenCombined sources1
Binding sitei168Coenzyme MCombined sources1
Metal bindingi233Zinc 2; via tele nitrogenCombined sources1

GO - Molecular functioni

Keywordsi

LigandMetal-bindingCombined sources, ZincCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Metallo-beta-lactamaseImported
Gene namesi
Name:SMB-1Imported
OrganismiSerratia marcescensImported
Taxonomic identifieri615 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeSerratia

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500347625319 – 280Sequence analysisAdd BLAST262

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi180 ↔ 185Combined sources
Disulfide bondi226 ↔ 260Combined sources

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3VPEX-ray1.60A19-280[»]
3VQZX-ray2.20A19-280[»]
5AXOX-ray1.39A19-280[»]
5AXRX-ray2.10A19-280[»]
5AYAX-ray2.02A19-280[»]
5B15X-ray1.39A19-280[»]
5B1UX-ray1.57A19-280[»]
SMRiG5ELM3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 233Lactamase_BInterPro annotationAdd BLAST191

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di3.60.15.10. 1 hit.
InterProiView protein in InterPro
IPR001279. Metallo-B-lactamas.
IPR036866. Metallo-hydrolase/OxRdtase.
PfamiView protein in Pfam
PF00753. Lactamase_B. 1 hit.
SMARTiView protein in SMART
SM00849. Lactamase_B. 1 hit.
SUPFAMiSSF56281. SSF56281. 1 hit.

Sequencei

Sequence statusi: Complete.

G5ELM3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIIASLILA AFASVAQAQD RDWSSPQQPF TIYGNTHYVG TGGISAVLLS
60 70 80 90 100
SPQGHILVDG TTEKGAQVVA ANIRAMGFKL SDVKYILSTH SHEDHAGGIS
110 120 130 140 150
AMQKLTGATV LAGAANVDTL RTGVSPKSDP QFGSLSNFPG SAKVRAVADG
160 170 180 190 200
ELVKLGPLAV KAHATPGHTE GGITWTWQSC EQGKCKDVVF ADSLTAVSAD
210 220 230 240 250
SYRFSDHPEV VASLRGSFEA VEKLSCDIAI AAHPEVNDMW TRQQRAAKEG
260 270 280
NSAYVDNGAC RAIAAAGRKR LETRLASEKR
Length:280
Mass (Da):29,518
Last modified:January 25, 2012 - v1
Checksum:i9F3E9CE4F4EFCBBD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB636283 Genomic DNA. Translation: BAL14456.1.
RefSeqiWP_063864723.1. NG_050133.1.

Similar proteinsi

Entry informationi

Entry nameiG5ELM3_SERMA
AccessioniPrimary (citable) accession number: G5ELM3
Entry historyiIntegrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: October 25, 2017
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources