Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

G5ELM3 (G5ELM3_SERMA) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 9. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:SMB-1 EMBL BAL14456.1
OrganismSerratia marcescens EMBL BAL14456.1
Taxonomic identifier615 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSerratia

Protein attributes

Sequence length280 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region80 – 812Sulfate 2 binding
Region207 – 2104Sulfate 3 binding

Sites

Metal binding881Sodium; via carbonyl oxygen PDB 3VQZ
Metal binding891Sodium; via carbonyl oxygen PDB 3VQZ
Metal binding901Zinc 1; via tele nitrogen PDB 3VPE PDB 3VQZ
Metal binding921Zinc 1; via pros nitrogen PDB 3VPE PDB 3VQZ
Metal binding941Zinc 2 PDB 3VPE PDB 3VQZ
Metal binding951Zinc 2; via tele nitrogen PDB 3VPE PDB 3VQZ
Metal binding1131Sodium; via amide nitrogen PDB 3VQZ
Metal binding1681Zinc 1; via tele nitrogen PDB 3VPE PDB 3VQZ
Metal binding1711Sodium; via carbonyl oxygen PDB 3VQZ
Metal binding2331Zinc 2; via tele nitrogen PDB 3VPE PDB 3VQZ
Binding site241Sulfate 1
Binding site641Sulfate 1
Binding site741Sulfate 2
Binding site1941Acetate 1; via amide nitrogen
Binding site1981Acetate 2; via amide nitrogen
Binding site2371Acetate 3
Binding site2421Acetate 3
Binding site2741Acetate 2

Sequences

Sequence LengthMass (Da)Tools
G5ELM3 [UniParc].

Last modified January 25, 2012. Version 1.
Checksum: 9F3E9CE4F4EFCBBD

FASTA28029,518
        10         20         30         40         50         60 
MKIIASLILA AFASVAQAQD RDWSSPQQPF TIYGNTHYVG TGGISAVLLS SPQGHILVDG 

        70         80         90        100        110        120 
TTEKGAQVVA ANIRAMGFKL SDVKYILSTH SHEDHAGGIS AMQKLTGATV LAGAANVDTL 

       130        140        150        160        170        180 
RTGVSPKSDP QFGSLSNFPG SAKVRAVADG ELVKLGPLAV KAHATPGHTE GGITWTWQSC 

       190        200        210        220        230        240 
EQGKCKDVVF ADSLTAVSAD SYRFSDHPEV VASLRGSFEA VEKLSCDIAI AAHPEVNDMW 

       250        260        270        280 
TRQQRAAKEG NSAYVDNGAC RAIAAAGRKR LETRLASEKR 

« Hide

References

[1]"SMB-1, a Novel Subclass B3 Metallo-beta-Lactamase, Associated with ISCR1 and a Class 1 Integron, from a Carbapenem-Resistant Serratia marcescens Clinical Isolate."
Wachino J., Yoshida H., Yamane K., Suzuki S., Matsui M., Yamagishi T., Tsutsui A., Konda T., Shibayama K., Arakawa Y.
Antimicrob. Agents Chemother. 55:5143-5149(2011)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 148 EMBL BAL14456.1.
[2]"Structural insights into the subclass B3 metallo-?-lactamase SMB-1 and the mode of inhibition by the common metallo-?-lactamase inhibitor mercaptoacetate."
Wachino J., Yamaguchi Y., Mori S., Kurosaki H., Arakawa Y., Shibayama K.
Antimicrob. Agents Chemother. 57:101-109(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) OF 19-280 IN COMPLEX WITH ACETATE; SODIUM; SULFATE AND ZINC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB636283 Genomic DNA. Translation: BAL14456.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3VPEX-ray1.60A19-280[»]
3VQZX-ray2.20A19-280[»]
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.60.15.10. 1 hit.
InterProIPR001279. Beta-lactamas-like.
[Graphical view]
PfamPF00753. Lactamase_B. 1 hit.
[Graphical view]
SMARTSM00849. Lactamase_B. 1 hit.
[Graphical view]
SUPFAMSSF56281. SSF56281. 1 hit.
ProtoNetSearch...

Entry information

Entry nameG5ELM3_SERMA
AccessionPrimary (citable) accession number: G5ELM3
Entry history
Integrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: June 11, 2014
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)