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Protein
Submitted name:

SeRPin

Gene

srp-6

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, ProteaseImported

Enzyme and pathway databases

ReactomeiR-CEL-114608 Platelet degranulation
R-CEL-140837 Intrinsic Pathway of Fibrin Clot Formation
R-CEL-140875 Common Pathway of Fibrin Clot Formation
R-CEL-1650814 Collagen biosynthesis and modifying enzymes
R-CEL-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-CEL-75205 Dissolution of Fibrin Clot
R-CEL-8957275 Post-translational protein phosphorylation

Protein family/group databases

MEROPSiI04.081

Names & Taxonomyi

Protein namesi
Submitted name:
SeRPinImported
Submitted name:
Serine or cysteine protease inhibitorImported
Gene namesi
Name:srp-6Imported
ORF Names:C03G6.19Imported, CELE_C03G6.19Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiC03G6.19 ; CE27579 ; WBGene00005647 ; srp-6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiWBGene00005647

Interactioni

Protein-protein interaction databases

STRINGi6239.C03G6.19

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 372SERPINInterPro annotationAdd BLAST351

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00900000140788
KOiK13963
OMAiHDEINSW
OrthoDBiEOG091G0ION

Family and domain databases

InterProiView protein in InterPro
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit

Sequencei

Sequence statusi: Complete.

G5EFH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDSSSDEKM GLLLHSETDF GLSLLRQQNL TESFVFSPLS IALALSLVHV
60 70 80 90 100
AAKGETRDEI RKALLNGATD EELEQHFSNI SAGLLVAEKG TEVNVANHIF
110 120 130 140 150
SRKTFTIKKL YLNDVKKLYN AGASQLNFED QEASAEAINN FVSENTKGHI
160 170 180 190 200
KKIINPDSIS EELVAVLTNA FYFKANWQTK FKKESTYKRE FFSSENSKRE
210 220 230 240 250
TEFLHSRNSN RKYSENGQFQ VLSLPYKDTS FALSIFLPKT RFGLSEALQN
260 270 280 290 300
LDSVTIQQLM SNTSNTLVNI AMPKWKIETA LGLNRALMAV GIEKAFTDSA
310 320 330 340 350
DLSNFADGIY ISQAAHKALI EVDEDGTVAA AATTISFSLT SVFIPAEEPI
360 370
EFTADHPFLF ILSKDNHPLF IGIHN
Length:375
Mass (Da):41,696
Last modified:December 14, 2011 - v1
Checksum:iBEFE7D31BEF0275E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY525082 mRNA Translation: AAS13530.1
BX284605 Genomic DNA Translation: CCD62703.1
PIRiT25504
RefSeqiNP_504890.1, NM_072489.5
UniGeneiCel.23464

Genome annotation databases

EnsemblMetazoaiC03G6.19; C03G6.19; WBGene00005647
GeneIDi179125
KEGGicel:CELE_C03G6.19

Similar proteinsi

Entry informationi

Entry nameiG5EFH4_CAEEL
AccessioniPrimary (citable) accession number: G5EFH4
Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: April 25, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported