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G5EFA4

- G5EFA4_CAEEL

UniProt

G5EFA4 - G5EFA4_CAEEL

Protein
Submitted name:

KIN-4 protein

Gene

kin-4

Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (14 Dec 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. magnesium ion binding Source: InterPro
    3. protein serine/threonine kinase activity Source: InterPro

    Keywords - Molecular functioni

    TransferaseImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    KIN-4 proteinImported (EC:2.7.1.37Imported)
    Submitted name:
    Protein KIN-4, isoform aImported
    Gene namesi
    Name:kin-4Imported
    ORF Names:C10C6.1Imported, CELE_C10C6.1Imported
    OrganismiCaenorhabditis elegansImported
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome IV

    Organism-specific databases

    WormBaseiC10C6.1a; CE39132; WBGene00002192; kin-4.

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 PDZ (DHR) domain.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00530000063286.
    KOiK08789.

    Family and domain databases

    Gene3Di1.20.1480.20. 2 hits.
    2.30.42.10. 1 hit.
    InterProiIPR011009. Kinase-like_dom.
    IPR015022. MA_Ser/Thr_Kinase_dom.
    IPR023142. MAST_pre-PK_dom.
    IPR001478. PDZ.
    IPR000719. Prot_kinase_dom.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF08926. DUF1908. 2 hits.
    PF00595. PDZ. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00228. PDZ. 1 hit.
    SM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF140482. SSF140482. 2 hits.
    SSF50156. SSF50156. 1 hit.
    SSF56112. SSF56112. 1 hit.
    PROSITEiPS50106. PDZ. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G5EFA4-1 [UniParc]FASTAAdd to Basket

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    MIPPRRSFHR PQGGGGNDSS DSNSNVERLL KRNRRRTMAI HGVETEPGQT     50
    AASTGWTSAS MTNLCRVRSS LGHSDPQLSS SSTNSFNTST SSLHPATKSS 100
    TTALSSFSTS SANRSPANRP SLHSSTSPVT LQRCRSPMRV PQRSTSSSHN 150
    FGAAGAGPSS SGSSVHSGTI TLRTYSARNG SSLMAPVQDT RRWSLASLPS 200
    TSGYGTPGTG SNSGVSSQYS SSEQIGEMLD QTRISGPVRQ NSSRFDSNDS 250
    YDDMASHQQA AAQNAFLNRP RSRSLTSPMK FLNEYNIEMV NRTSVYKERF 300
    PRAKLQMEER LNAFVAENGP LSGGISQQSA RDDTDRVDDL SARQSGSSSG 350
    LKAKDSVEEA VMRSRRSTVL EAESYADRSL LRLIGDGATR FLHHQIVEIA 400
    LDCLGKSKDD LITCSYFCEM SQRLEETLNE AQMKTSPESL EYLSKLVKKL 450
    LMIVSRPARL LECLEFDPDE FYHLLEEAEG VVREQLGSGT ARVPDLPQYI 500
    IGKLGLDRDP LIDSTEHVDS SENTHATTSG TTSAKGAGSA WQETNRAPCE 550
    DDFDTIRLVS NGAYGAVYLV RHRETRQRFA LKKMNKQTLM LRNQVDQVFA 600
    ERDILTMADN PFVVSFYGSF ETRQYLCMLM EYVEGGDCAA LLKSAGTLPV 650
    ELVRLYVAET ILAIEYLHSY GIVHRDLKPD NLLITAMGHI KLTDFGLSKI 700
    GLMNRTTLVA EGYDAVVETQ QFQDKQLCGT PEYIAPEVIL RRGYGKPVDW 750
    WALGIILYEF LVGIVPFFGE TPEALFSKVI SEDVEYPEED EALPPEAADL 800
    CRRLLEKNPA ERLGTLNGAA QLMAHEFFIL LDFTSLLRQK AEFVPQLDNE 850
    EDTSYFDTRT DRYNHEAESC GEEEIVGSSA ASSMMFHSFS TASPRHSIVS 900
    IDPAHLPHLL STANAAAKEI ERSHSVSMSS RPETRPERSY STGQAPPELF 950
    KVGDDNTSTA VNLRRRFSAQ RHNVSTTSSS GTGSGTCFAT AASSTDSSID 1000
    ASSLPLFQPP SRSSIAERGS RSPLPKFSIS CEGEAGVSRS GDDHDDLDDS 1050
    RNSTIVSTAS SGGADETVRF RRQSSGRTPA SQLQLVIPSI SSSQSSQSAE 1100
    PARETCYVMY PSGPSTSVGS QLSPGGASVS SASSSNDVGS PHPLPLHHEH 1150
    PLTSHDSSAA SSSTAPSKTI TIRKGPFGFG FTLKSVRVYL GEHSEYYTIE 1200
    HIVTAVVEGS PAFHANLQAE DMITHVNGHP VHNLTHPQLM HRLLANGNEL 1250
    ILRLVPLANT SIREGAARRT VGKMARKKPK RPQRRVVPLE KKTRKPSALL 1300
    RRLSGKRATN DIVPGSSSQK QAFMPRSASS QDGCILTHLP GTSKISQQEA 1350
    SQEPSTSSQG MVRRSVNEIE TNRPSSLRST SNSHHHHHHP ASTSSVASAP 1400
    ATLPSTTPSN LSRMASSSPS SSASNSGTSS PAATSSGISI VKQKSQSIAV 1450
    SPLARDTRMR SPSPSHLHHR PASSSYTTRP DGVVTPATSS SPNNSGFVQD 1500
    LISSRQSPNL SARRRSYQPT TTTSMIVPPT THHLRGFSAA AQSAQDLLNR 1550
    LLPKQDNNSD SGSKK 1565
    Length:1,565
    Mass (Da):169,787
    Last modified:December 14, 2011 - v1
    Checksum:iB47054B5917B0176
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z83217 Genomic DNA. Translation: CAB05684.2.
    AM086627 mRNA. Translation: CAJ31105.1.
    PIRiT19188.
    RefSeqiNP_001255557.1. NM_001268628.1.
    UniGeneiCel.22672.

    Genome annotation databases

    EnsemblMetazoaiC10C6.1a; C10C6.1a; WBGene00002192.
    GeneIDi178068.
    KEGGicel:CELE_C10C6.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z83217 Genomic DNA. Translation: CAB05684.2 .
    AM086627 mRNA. Translation: CAJ31105.1 .
    PIRi T19188.
    RefSeqi NP_001255557.1. NM_001268628.1.
    UniGenei Cel.22672.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai C10C6.1a ; C10C6.1a ; WBGene00002192 .
    GeneIDi 178068.
    KEGGi cel:CELE_C10C6.1.

    Organism-specific databases

    CTDi 178068.
    WormBasei C10C6.1a ; CE39132 ; WBGene00002192 ; kin-4.

    Phylogenomic databases

    GeneTreei ENSGT00530000063286.
    KOi K08789.

    Miscellaneous databases

    NextBioi 899580.

    Family and domain databases

    Gene3Di 1.20.1480.20. 2 hits.
    2.30.42.10. 1 hit.
    InterProi IPR011009. Kinase-like_dom.
    IPR015022. MA_Ser/Thr_Kinase_dom.
    IPR023142. MAST_pre-PK_dom.
    IPR001478. PDZ.
    IPR000719. Prot_kinase_dom.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF08926. DUF1908. 2 hits.
    PF00595. PDZ. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00228. PDZ. 1 hit.
    SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF140482. SSF140482. 2 hits.
    SSF50156. SSF50156. 1 hit.
    SSF56112. SSF56112. 1 hit.
    PROSITEi PS50106. PDZ. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. WormBase Consortium
      White S.
      Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Bristol N2Imported.
    2. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2Imported.
    3. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      Caenorhabditis elegans Sequencing Consortium
      Science 282:2012-2018(1998)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Bristol N2Imported.
    4. "KIN-4 is a novel Diacylglycerol Kinase 1 (DGK-1) binding protein required for efficient dopamine and serotonin signaling in Caenorhabditis elegans."
      Morrison P.R., McMullan R., Pitcher J., Nurrish S.J.
      Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: N2Imported.

    Entry informationi

    Entry nameiG5EFA4_CAEEL
    AccessioniPrimary (citable) accession number: G5EFA4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 14, 2011
    Last sequence update: December 14, 2011
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3