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Protein
Submitted name:

Mitochondrial elongation factor Tu homologue

Gene

tufm-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-KW
  3. translation elongation factor activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Mitochondrial elongation factor Tu homologueImported
Submitted name:
Protein TUFM-2Imported
Gene namesi
Name:tufm-2Imported
ORF Names:C43E11.4Imported, CELE_C43E11.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome I

Organism-specific databases

WormBaseiC43E11.4; CE32610; WBGene00007001; tufm-2.

Structurei

3D structure databases

ProteinModelPortaliG5EDF5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00550000074682.
KOiK02358.
OMAiISGASQM.
OrthoDBiEOG73BVCN.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G5EDF5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNPAALSAFT RSLLFNRCST SSFCNSITRN AVAFFATAAA TPKINVNVGT
60 70 80 90 100
IGHIDHGKTT LTSAITRVQA KKGFAKHIKF DEIDKGKEEK KRGITINVAH
110 120 130 140 150
IGYESPLRRY SHTDCPGHSD FIKNMICGTS QMDVAVLVIA ATDGVMEQTK
160 170 180 190 200
EHLILAKQVG VKNMAIFINK ADLVEEDDLD LVEMEARELL SLHGFNGDAT
210 220 230 240 250
PVIRGSALSA LEGQDISCIE RLIDALDSLP EPDRNEKDTF VMPIASKTAI
260 270 280 290 300
TGRGTVIVGT LERGVLKKGD KVEIKGDGQT LQTTASDIQV FGKSVKEVRA
310 320 330 340 350
GDHCGVLCRG VKGDTVKRGM WAGHPGAVTI TNRVKVELYL LSEAENGRKI
360 370 380 390 400
GIRTGFTDKM YCSTWDQVGR FDMSNELLMP GEHTSATVLL MKDMPLRKGM
410 420 430
PFTLREGSSK TTIARGIISD LEDHVAVEKH NLKKSAEKM
Length:439
Mass (Da):47,831
Last modified:December 14, 2011 - v1
Checksum:i5EE533C1A3636D5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB010028 mRNA. Translation: BAA31345.1.
FO080612 Genomic DNA. Translation: CCD65152.1.
PIRiT37273.
RefSeqiNP_491338.2. NM_058937.4.
UniGeneiCel.19656.

Genome annotation databases

EnsemblMetazoaiC43E11.4; C43E11.4; WBGene00007001.
GeneIDi172024.
KEGGicel:CELE_C43E11.4.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB010028 mRNA. Translation: BAA31345.1.
FO080612 Genomic DNA. Translation: CCD65152.1.
PIRiT37273.
RefSeqiNP_491338.2. NM_058937.4.
UniGeneiCel.19656.

3D structure databases

ProteinModelPortaliG5EDF5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC43E11.4; C43E11.4; WBGene00007001.
GeneIDi172024.
KEGGicel:CELE_C43E11.4.

Organism-specific databases

CTDi172024.
WormBaseiC43E11.4; CE32610; WBGene00007001; tufm-2.

Phylogenomic databases

GeneTreeiENSGT00550000074682.
KOiK02358.
OMAiISGASQM.
OrthoDBiEOG73BVCN.

Miscellaneous databases

NextBioi873713.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. WormBase Consortium
    Gattung S., Scheet P.
    Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Bristol N2Imported.
  2. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Science 282:2012-2018(1998)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Bristol N2Imported.
  3. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.
  4. "A unique serine-specific elongation factor Tu found in nematode mitochondria."
    Ohtsuki T., Sato A., Watanabe Y., Watanabe K.
    Nat. Struct. Biol. 9:669-673(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  5. "Identification of the residues involved in the unique serine specificity of Caenorhabditis elegans mitochondrial EF-Tu2."
    Sato A., Watanabe Y., Suzuki T., Komiyama M., Watanabe K., Ohtsuki T.
    Biochemistry 45:10920-10927(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiG5EDF5_CAEEL
AccessioniPrimary (citable) accession number: G5EDF5
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: February 4, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.