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G5ECU1

- G5ECU1_CAEEL

UniProt

G5ECU1 - G5ECU1_CAEEL

Protein
Submitted name:

Protein SKR-1

Gene

skr-1

Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. protein binding Source: IntAct

    GO - Biological processi

    1. positive regulation of apoptotic process Source: WormBase
    2. ubiquitin-dependent protein catabolic process Source: InterPro

    Enzyme and pathway databases

    ReactomeiREACT_205379. SCF-beta-TrCP mediated degradation of Emi1.
    REACT_219545. Cyclin D associated events in G1.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein SKR-1Imported
    Gene namesi
    Name:skr-1Imported
    ORF Names:CELE_F46A9.5Imported, F46A9.5Imported
    OrganismiCaenorhabditis elegansImported
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome I

    Organism-specific databases

    WormBaseiF46A9.5; CE10580; WBGene00004807; skr-1.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    CELE_C14B1.3Q179623EBI-323117,EBI-2003707
    CELE_F46F11.6P913053EBI-323117,EBI-2003766
    dre-1Q942513EBI-323117,EBI-314286
    fbxa-101G5EDX94EBI-323117,EBI-2003730
    fbxa-164O171984EBI-323117,EBI-2412975
    fbxa-196O165255EBI-323117,EBI-329491
    fog-2Q2YS434EBI-323117,EBI-2417735
    fsn-1Q182233EBI-323117,EBI-2003744
    sel-10Q937945EBI-323117,EBI-323098

    Protein-protein interaction databases

    IntActiG5ECU1. 19 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliG5ECU1.
    SMRiG5ECU1. Positions 16-174.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000012652.
    KOiK03094.
    OMAiVIQWCTY.
    PhylomeDBiG5ECU1.

    Family and domain databases

    Gene3Di3.30.710.10. 1 hit.
    InterProiIPR011333. BTB/POZ_fold.
    IPR016897. E3_ubiquit_lig_SCF_Skp.
    IPR001232. Skp1_comp.
    IPR016072. Skp1_comp_dimer.
    IPR016073. Skp1_comp_POZ.
    [Graphical view]
    PANTHERiPTHR11165. PTHR11165. 1 hit.
    PfamiPF01466. Skp1. 1 hit.
    PF03931. Skp1_POZ. 1 hit.
    [Graphical view]
    PIRSFiPIRSF028729. E3_ubiquit_lig_SCF_Skp. 1 hit.
    SMARTiSM00512. Skp1. 1 hit.
    [Graphical view]
    SUPFAMiSSF54695. SSF54695. 1 hit.
    SSF81382. SSF81382. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    G5ECU1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MADQKKVSEA AKEREIKISS SDNEIFLVPR NVIRLSNTIN TLLMDLGLDD    50
    EEGTNAEPIP VQNVTASILK KVISWCNHHH SDPISTEDSD NREKRTDDIG 100
    SWDVEFLKVD QGTLFELILA ANYLDIKGLL DVTCKTVANM IKGKSPEEIR 150
    RTFNIKNDFT PEEEEQIRKE NAWCED 176
    Length:176
    Mass (Da):20,032
    Last modified:December 14, 2011 - v1
    Checksum:i3FCDC4D52BC2DF35
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z81084, Z81072 Genomic DNA. Translation: CAB03110.1.
    PIRiT21573.
    RefSeqiNP_492513.1. NM_060112.5.
    UniGeneiCel.18311.

    Genome annotation databases

    EnsemblMetazoaiF46A9.5.1; F46A9.5.1; WBGene00004807.
    F46A9.5.2; F46A9.5.2; WBGene00004807.
    F46A9.5.3; F46A9.5.3; WBGene00004807.
    GeneIDi172775.
    KEGGicel:CELE_F46A9.5.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z81084 , Z81072 Genomic DNA. Translation: CAB03110.1 .
    PIRi T21573.
    RefSeqi NP_492513.1. NM_060112.5.
    UniGenei Cel.18311.

    3D structure databases

    ProteinModelPortali G5ECU1.
    SMRi G5ECU1. Positions 16-174.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi G5ECU1. 19 interactions.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai F46A9.5.1 ; F46A9.5.1 ; WBGene00004807 .
    F46A9.5.2 ; F46A9.5.2 ; WBGene00004807 .
    F46A9.5.3 ; F46A9.5.3 ; WBGene00004807 .
    GeneIDi 172775.
    KEGGi cel:CELE_F46A9.5.

    Organism-specific databases

    CTDi 172775.
    WormBasei F46A9.5 ; CE10580 ; WBGene00004807 ; skr-1.

    Phylogenomic databases

    GeneTreei ENSGT00390000012652.
    KOi K03094.
    OMAi VIQWCTY.
    PhylomeDBi G5ECU1.

    Enzyme and pathway databases

    Reactomei REACT_205379. SCF-beta-TrCP mediated degradation of Emi1.
    REACT_219545. Cyclin D associated events in G1.

    Miscellaneous databases

    NextBioi 876957.
    PROi G5ECU1.

    Family and domain databases

    Gene3Di 3.30.710.10. 1 hit.
    InterProi IPR011333. BTB/POZ_fold.
    IPR016897. E3_ubiquit_lig_SCF_Skp.
    IPR001232. Skp1_comp.
    IPR016072. Skp1_comp_dimer.
    IPR016073. Skp1_comp_POZ.
    [Graphical view ]
    PANTHERi PTHR11165. PTHR11165. 1 hit.
    Pfami PF01466. Skp1. 1 hit.
    PF03931. Skp1_POZ. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF028729. E3_ubiquit_lig_SCF_Skp. 1 hit.
    SMARTi SM00512. Skp1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54695. SSF54695. 1 hit.
    SSF81382. SSF81382. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2Imported.

    Entry informationi

    Entry nameiG5ECU1_CAEEL
    AccessioniPrimary (citable) accession number: G5ECU1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 14, 2011
    Last sequence update: December 14, 2011
    Last modified: October 1, 2014
    This is version 28 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3