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Protein

Aldose 1-epimerase

Gene

C01B4.6

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. aldose 1-epimerase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro

GO - Biological processi

  1. hexose metabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotaseUniRule annotation
Gene namesi
ORF Names:C01B4.6Imported, CELE_C01B4.6Imported, CELE_Y19D10A.16Imported, Y19D10A.16Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome V

Organism-specific databases

WormBaseiC01B4.6; CE20475; WBGene00015270.
Y19D10A.16; CE20475; WBGene00044734.

Structurei

3D structure databases

ProteinModelPortaliG5ECR6.
SMRiG5ECR6. Positions 2-330.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiG5ECR6.

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00510000047589.
KOiK01785.
OMAiYINETRY.
OrthoDBiEOG7V7666.
PhylomeDBiG5ECR6.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.

Sequencei

Sequence statusi: Complete.

G5ECR6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASGFIEIAN KQGLTATLLP FGATLAKLTF PDKNGKNQDL VLGFDTIDEF
60 70 80 90 100
EKDAASIGKT VGRVANRIKN STLHFDGKQY TMTPNNGPHY LHGGPNGLGY
110 120 130 140 150
RKWEVVRHAP ESVSFSVRAN EQDDGLPGDA KIDVTYTVND RNQLIIEHHA
160 170 180 190 200
TCDTPGLLAL TNHAYWNLDG SDTVAEHFLE MEADEFVEVD DTFCPTGAIR
210 220 230 240 250
SVTDTGFDFR SGKQLKESGK DAEELLDLDN DLVITKKTPP STPSTYLRFW
260 270 280 290 300
SEKSGIELSI TTSYPVIHLY ASKFLDCKGK KGEHYKANKA LAIEPQFHSA
310 320 330
APNFDHFPDV SLRPGDHYCQ EIVYTFSHVN
Length:330
Mass (Da):36,587
Last modified:December 14, 2011 - v1
Checksum:i3C76442A295E0439
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080244 Genomic DNA. Translation: CCD62289.1.
FO080522 Genomic DNA. Translation: CCD64372.1.
PIRiT33944.
RefSeqiNP_001041189.1. NM_001047724.1.
NP_503684.1. NM_071283.1.
UniGeneiCel.34261.
Cel.34516.

Genome annotation databases

EnsemblMetazoaiC01B4.6; C01B4.6; WBGene00015270.
Y19D10A.16; Y19D10A.16; WBGene00044734.
GeneIDi178723.
4363084.
KEGGicel:CELE_C01B4.6.
cel:CELE_Y19D10A.16.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080244 Genomic DNA. Translation: CCD62289.1.
FO080522 Genomic DNA. Translation: CCD64372.1.
PIRiT33944.
RefSeqiNP_001041189.1. NM_001047724.1.
NP_503684.1. NM_071283.1.
UniGeneiCel.34261.
Cel.34516.

3D structure databases

ProteinModelPortaliG5ECR6.
SMRiG5ECR6. Positions 2-330.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC01B4.6; C01B4.6; WBGene00015270.
Y19D10A.16; Y19D10A.16; WBGene00044734.
GeneIDi178723.
4363084.
KEGGicel:CELE_C01B4.6.
cel:CELE_Y19D10A.16.

Organism-specific databases

CTDi178723.
4363084.
WormBaseiC01B4.6; CE20475; WBGene00015270.
Y19D10A.16; CE20475; WBGene00044734.

Phylogenomic databases

GeneTreeiENSGT00510000047589.
KOiK01785.
OMAiYINETRY.
OrthoDBiEOG7V7666.
PhylomeDBiG5ECR6.

Enzyme and pathway databases

UniPathwayiUPA00242.

Miscellaneous databases

EvolutionaryTraceiG5ECR6.
NextBioi902282.
PROiG5ECR6.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.
  2. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Science 282:2012-2018(1998)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Bristol N2Imported.
  3. WormBase Consortium
    Smith A., Wamsley P., Fronick W.
    Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Bristol N2Imported.
  4. WormBase Consortium
    Johnson D.
    Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiG5ECR6_CAEEL
AccessioniPrimary (citable) accession number: G5ECR6
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: March 4, 2015
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.